CAK-Cyclin-dependent Activating Kinase: a key kinase in cell cycle control and a target for drugs?
about
Targeting CDK6 in cancer: State of the art and new insightsChanges in oscillatory dynamics in the cell cycle of early Xenopus laevis embryosFunction of Conserved Topological Regions within the Saccharomyces cerevisiae Basal Transcription Factor TFIIHAutomated integration of monolith-based protein separation with on-plate digestion for mass spectrometric analysis of esophageal adenocarcinoma human epithelial samples.Human synthetic lethal inference as potential anti-cancer target gene detectionCyclin H expression is increased in GIST with very-high risk of malignancyThe development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity.Cancer models in Caenorhabditis elegans.MicroRNA-23b regulates cyclin-dependent kinase-activating kinase complex through cyclin H repression to modulate endothelial transcription and growth under flowDevelopment of a cyclin-dependent kinase inhibitor devoid of ABC transporter-dependent drug resistanceA novel CDK7 inhibitor of the Pyrazolotriazine class exerts broad-spectrum antiviral activity at nanomolar concentrations.Platinum-induced neurotoxicity and preventive strategies: past, present, and futureRapid changes in gene expression direct rapid shifts in intestinal form and function in the Burmese python after feeding.Two susceptibility loci identified for prostate cancer aggressiveness.Insights on Structural Characteristics and Ligand Binding Mechanisms of CDK2Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion.A phosphorylation-independent role for the yeast cyclin-dependent kinase activating kinase Cak1.Cell cycle, cytoskeleton dynamics and beyond: the many functions of cyclins and CDK inhibitorsNSun2 Promotes Cell Growth via Elevating Cyclin-Dependent Kinase 1 Translation.Amplification Target ADRM1: Role as an Oncogene and Therapeutic Target for Ovarian Cancer.The CDK Network: Linking Cycles of Cell Division and Gene Expression.A prognostic signature of G(2) checkpoint function in melanoma cell lines.Tighter αC-helix-αL16-helix interactions seem to make p38α less prone to activation by autophosphorylation than Hog1.A novel microtubule inhibitor, MT3-037, causes cancer cell apoptosis by inducing mitotic arrest and interfering with microtubule dynamics.Extrapolating the effect of deleterious nsSNPs in the binding adaptability of flavopiridol with CDK7 protein: a molecular dynamics approachNeuron-NG2 cell synapses: novel functions for regulating NG2 cell proliferation and differentiation.Phosphorylation of cyclin-dependent kinase 2 peptides enhances metal bindingPathway Analysis Based on Attractor and Cross Talk in Colon Cancer.In vivo roles of CDC25 phosphatases: biological insight into the anti-cancer therapeutic targetsCyclin-dependent kinases: bridging their structure and function through computations.Cell cycle-related kinase in carcinogenesisOverview of cyclins D1 function in cancer and the CDK inhibitor landscape: past and present.Cell cycle progression in response to oxygen levels.The roles and therapeutic potential of cyclin-dependent kinases (CDKs) in sarcoma.The newly synthesized 2-arylnaphthyridin-4-one, CSC-3436, induces apoptosis of non-small cell lung cancer cells by inhibiting tubulin dynamics and activating CDK1.Low expression of cyclinH and cyclin-dependent kinase 7 can decrease the proliferation of human esophageal squamous cell carcinoma.Binding Mechanism of Inhibitors to CDK5/p25 Complex: Free Energy Calculation and Ranking Aggregation Analysis.Coordinated activation of the origin licensing factor CDC6 and CDK2 in resting human fibroblasts expressing SV40 small T antigen and cyclin E.Phosphorylation of retinoblastoma protein by viral protein with cyclin-dependent kinase function.
P2860
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P2860
CAK-Cyclin-dependent Activating Kinase: a key kinase in cell cycle control and a target for drugs?
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
CAK-Cyclin-dependent Activatin ...... ontrol and a target for drugs?
@ast
CAK-Cyclin-dependent Activatin ...... ontrol and a target for drugs?
@en
CAK-Cyclin-dependent Activatin ...... ontrol and a target for drugs?
@en-gb
CAK-Cyclin-dependent Activatin ...... ontrol and a target for drugs?
@nl
type
label
CAK-Cyclin-dependent Activatin ...... ontrol and a target for drugs?
@ast
CAK-Cyclin-dependent Activatin ...... ontrol and a target for drugs?
@en
CAK-Cyclin-dependent Activatin ...... ontrol and a target for drugs?
@en-gb
CAK-Cyclin-dependent Activatin ...... ontrol and a target for drugs?
@nl
prefLabel
CAK-Cyclin-dependent Activatin ...... ontrol and a target for drugs?
@ast
CAK-Cyclin-dependent Activatin ...... ontrol and a target for drugs?
@en
CAK-Cyclin-dependent Activatin ...... ontrol and a target for drugs?
@en-gb
CAK-Cyclin-dependent Activatin ...... ontrol and a target for drugs?
@nl
P3181
P356
P1433
P1476
CAK-Cyclin-dependent Activatin ...... ontrol and a target for drugs?
@en
P2093
Graziano Lolli
Louise N Johnson
P3181
P356
10.4161/CC.4.4.1607
P407
P577
2005-04-01T00:00:00Z