PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response
about
Trial watch - inhibiting PARP enzymes for anticancer therapyIntracellular Mono-ADP-Ribosylation in Signaling and DiseaseADP-ribosyltransferases and poly ADP-ribosylationEpigallocatechin-3-gallate enhances ER stress-induced cancer cell apoptosis by directly targeting PARP16 activity.Family-wide analysis of poly(ADP-ribose) polymerase activityA role of intracellular mono-ADP-ribosylation in cancer biology.Ubiquitination of inositol-requiring enzyme 1 (IRE1) by the E3 ligase CHIP mediates the IRE1/TRAF2/JNK pathway.EHMT2 inhibitor BIX-01294 induces apoptosis through PMAIP1-USP9X-MCL1 axis in human bladder cancer cellsPoly(ADP-ribose) polymerase-13 and RNA regulation in immunity and cancer.PARPs and ADP-Ribosylation: 50 Years … and Counting.New PARP targets for cancer therapyVirus-Host Interactions and the ARTD/PARP Family of EnzymesPARP6 is a Regulator of Hippocampal Dendritic Morphogenesis.E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling.A systematic analysis of the PARP protein family identifies new functions critical for cell physiology.IRE1: ER stress sensor and cell fate executor.Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue.The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection.Endoplasmic Reticulum Stress and Related Pathological Processes.PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes.UPR Signal Activation by Luminal Sensor Domains.Expanding functions of intracellular resident mono-ADP-ribosylation in cell physiology.ADP-ribosylation: activation, recognition, and removalRegulation of vascular endothelial growth factor by metabolic context of the cell.Proteostasis control by the unfolded protein responsePDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR)Latonduine Analogs Restore F508del-Cystic Fibrosis Transmembrane Conductance Regulator Trafficking through the Modulation of Poly-ADP Ribose Polymerase 3 and Poly-ADP Ribose Polymerase 16 Activity.c-Jun N-terminal Kinase-Dependent Endoplasmic Reticulum Stress Pathway is Critically Involved in Arjunic Acid Induced Apoptosis in Non-Small Cell Lung Cancer Cells.New directions in poly(ADP-ribose) polymerase biology.Interaction of Nck1 and PERK phosphorylated at Y⁵⁶¹ negatively modulates PERK activity and PERK regulation of pancreatic β-cell proinsulin content.ENPP1 processes protein ADP-ribosylation in vitro.Chromatin to Clinic: The Molecular Rationale for PARP1 Inhibitor Function.A novel link between Fic (filamentation induced by cAMP)-mediated adenylylation/AMPylation and the unfolded protein responseDistribution of protein poly(ADP-ribosyl)ation systems across all domains of life.Erratum: Proteostasis control by the unfolded protein response.In vivo vizualisation of mono-ADP-ribosylation by dPARP16 upon amino-acid starvation.New Quantitative Mass Spectrometry Approaches Reveal Different ADP-ribosylation Phases Dependent On the Levels of Oxidative Stress.Membrane lipid saturation activates IRE1α without inducing clustering.AKT-mTOR signaling modulates the dynamics of IRE1 RNAse activity by regulating ER-mitochondria contacts.Viral Macrodomains: Unique Mediators of Viral Replication and Pathogenesis.
P2860
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P2860
PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
PARP16 is a tail-anchored endo ...... ated unfolded protein response
@ast
PARP16 is a tail-anchored endo ...... ated unfolded protein response
@en
PARP16 is a tail-anchored endo ...... ated unfolded protein response
@en-gb
PARP16 is a tail-anchored endo ...... ated unfolded protein response
@nl
type
label
PARP16 is a tail-anchored endo ...... ated unfolded protein response
@ast
PARP16 is a tail-anchored endo ...... ated unfolded protein response
@en
PARP16 is a tail-anchored endo ...... ated unfolded protein response
@en-gb
PARP16 is a tail-anchored endo ...... ated unfolded protein response
@nl
prefLabel
PARP16 is a tail-anchored endo ...... ated unfolded protein response
@ast
PARP16 is a tail-anchored endo ...... ated unfolded protein response
@en
PARP16 is a tail-anchored endo ...... ated unfolded protein response
@en-gb
PARP16 is a tail-anchored endo ...... ated unfolded protein response
@nl
P2860
P921
P3181
P356
P1433
P1476
PARP16 is a tail-anchored endo ...... ated unfolded protein response
@en
P2093
P2860
P2888
P304
P3181
P356
10.1038/NCB2593
P407
P577
2012-11-01T00:00:00Z
P5875
P6179
1045207486