Pacemaker channel dysfunction in a patient with sinus node disease
about
Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node diseaseTbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atriaMode shifts in the voltage gating of the mouse and human HCN2 and HCN4 channelsNeuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets: Promise and PitfallsHyperpolarization-activated current, If, in mathematical models of rabbit sinoatrial node pacemaker cellsIon Channels in the HeartEmerging directions in the genetics of atrial fibrillationHCN channels and heart ratePopeye domain-containing proteins and stress-mediated modulation of cardiac pacemakingFunny channel gene mutations associated with arrhythmiasDefects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture.Structural Basis for the cAMP-dependent Gating in the Human HCN4 ChannelInherited bradyarrhythmia: A diverse genetic backgroundPacemaker activity of the human sinoatrial node: an update on the effects of mutations in HCN4 on the hyperpolarization-activated currentThe cardiac conduction systemCongenital sick sinus syndrome caused by recessive mutations in the cardiac sodium channel gene (SCN5A)Inherited conduction system abnormalities--one group of diseases, many genesPopeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in miceThe murine HCN3 gene encodes a hyperpolarization-activated cation channel with slow kinetics and unique response to cyclic nucleotidesGenetics of sick sinus syndromeFunctional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia.Pacemaker current inhibition in experimental human cardiac sympathetic activation: a double-blind, randomized, crossover study.Genetic mapping of a new heart rate QTL on chromosome 8 of spontaneously hypertensive rats.I(f) and SR Ca(2+) release both contribute to pacemaker activity in canine sinoatrial node cellsBeyond the Electrocardiogram: Mutations in Cardiac Ion Channel Genes Underlie Nonarrhythmic Phenotypes.Genetics and Sinus Node Dysfunction.PP2 prevents β-adrenergic stimulation of cardiac pacemaker activity.Mechanistic links between Na+ channel (SCN5A) mutations and impaired cardiac pacemaking in sick sinus syndrome.Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder.A novel trafficking-defective HCN4 mutation is associated with early-onset atrial fibrillation.A novel mutation in the HCN4 gene causes symptomatic sinus bradycardia in Moroccan Jews.Resting heart rate and risk of sudden cardiac death in the general population: influence of left ventricular systolic dysfunction and heart rate-modulating drugs.Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivationOverview of Basic Mechanisms of Cardiac ArrhythmiaHCN channels in behavior and neurological disease: too hyper or not active enough?The Contribution of HCN4 to normal sinus node function in humans and animal modelsOxidized CaMKII causes cardiac sinus node dysfunction in mice.Enhancement of Spontaneous Activity by HCN4 Overexpression in Mouse Embryonic Stem Cell-Derived Cardiomyocytes - A Possible Biological Pacemaker.The genetic basis for inherited forms of sinoatrial dysfunction and atrioventricular node dysfunctionAn N-terminal deletion variant of HCN1 in the epileptic WAG/Rij strain modulates HCN current densities.
P2860
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P2860
Pacemaker channel dysfunction in a patient with sinus node disease
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Pacemaker channel dysfunction in a patient with sinus node disease
@ast
Pacemaker channel dysfunction in a patient with sinus node disease
@en
Pacemaker channel dysfunction in a patient with sinus node disease
@en-gb
Pacemaker channel dysfunction in a patient with sinus node disease
@nl
type
label
Pacemaker channel dysfunction in a patient with sinus node disease
@ast
Pacemaker channel dysfunction in a patient with sinus node disease
@en
Pacemaker channel dysfunction in a patient with sinus node disease
@en-gb
Pacemaker channel dysfunction in a patient with sinus node disease
@nl
prefLabel
Pacemaker channel dysfunction in a patient with sinus node disease
@ast
Pacemaker channel dysfunction in a patient with sinus node disease
@en
Pacemaker channel dysfunction in a patient with sinus node disease
@en-gb
Pacemaker channel dysfunction in a patient with sinus node disease
@nl
P2093
P2860
P921
P3181
P1476
Pacemaker channel dysfunction in a patient with sinus node disease
@en
P2093
Dirk Isbrandt
Eric Schulze-Bahr
Olaf Pongs
Patrick Friederich
U Benjamin Kaupp
P2860
P304
P3181
P356
10.1172/JCI16387
10.1172/JCI200316387
P407
P577
2003-05-01T00:00:00Z