MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 binding
about
The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signalingThe tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritisMK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decayNot1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolinStructural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolinActivation of a nuclear Cdc2-related kinase within a mitogen-activated protein kinase-like TDY motif by autophosphorylation and cyclin-dependent protein kinase-activating kinase.The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase BActivation and function of the MAPKs and their substrates, the MAPK-activated protein kinasesThe roles of TTP and BRF proteins in regulated mRNA decayPhosphorylation of the ARE-binding protein DAZAP1 by ERK2 induces its dissociation from DAZPost-transcriptional Regulation of Immunological Responses through RiboclusteringCell type- and stimulus-specific mechanisms for post-transcriptional control of neutrophil chemokine gene expressionRegulation of AU-Rich Element RNA Binding Proteins by Phosphorylation and the Prolyl Isomerase Pin1p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1The control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatasesPhosphorylation of human tristetraprolin in response to its interaction with the Cbl interacting protein CIN85MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitmentBRF1 protein turnover and mRNA decay activity are regulated by protein kinase B at the same phosphorylation sitesProtor-2 interacts with tristetraprolin to regulate mRNA stability during stressThe AU-rich element mRNA decay-promoting activity of BRF1 is regulated by mitogen-activated protein kinase-activated protein kinase 2Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1The p38 MAPK pathway inhibits tristetraprolin-directed decay of interleukin-10 and pro-inflammatory mediator mRNAs in murine macrophagesDifferential expression and functional analysis of the tristetraprolin family during early differentiation of 3T3-L1 preadipocytesTristetraprolin inhibits poly(A)-tail synthesis in nuclear mRNA that contains AU-rich elements by interacting with poly(A)-binding protein nuclear 1Zfp36l3, a rodent X chromosome gene encoding a placenta-specific member of the Tristetraprolin family of CCCH tandem zinc finger proteinsSerotonin Receptor 4/6/7 and NR3C SignalingSerotonin Receptor 2 and ELK-SRF/GATA4 signalingComplex regulation and function of the inflammatory smooth muscle cell phenotype in atherosclerosisInhibition of tristetraprolin deadenylation by poly(A) binding protein.Identification of class I MHC-associated phosphopeptides as targets for cancer immunotherapy.MNK kinases regulate multiple TLR pathways and innate proinflammatory cytokines in macrophages.Functional analysis of KSRP interaction with the AU-rich element of interleukin-8 and identification of inflammatory mRNA targets.Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesisPRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis.Phosphorylation site analysis of the anti-inflammatory and mRNA-destabilizing protein tristetraprolin.MAPK-activated protein kinase 2 is required for mouse meiotic spindle assembly and kinetochore-microtubule attachment.Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatasesTreatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression.Pterostilbene 4'-β-Glucoside Protects against DSS-Induced Colitis via Induction of Tristetraprolin.Identification of a major phosphopeptide in human tristetraprolin by phosphopeptide mapping and mass spectrometry.
P2860
Q21145899-68E4C754-4AB3-4301-92A5-688C3FE0F9B8Q21195674-C6FB240E-6DBC-4672-90A8-67AF1F838ED3Q24316111-90B4CE24-4FF7-4192-9552-DFE7FF92CC17Q24338694-18711F7A-BFA2-4238-B803-D2E475F29C5FQ24339555-5FA6F7B9-552C-4A5E-B4D6-13F7E90ED3ECQ24531984-DD71922C-5905-41CE-8EDB-0F16C764AF70Q24558903-1497B5EF-FEB4-4BC7-97B9-C06A572A21D3Q24632768-774B7FD8-C574-469F-AB4C-27D50D2C853CQ24633013-136FE7BA-0A70-41FC-98DE-E2E421E150B9Q24673616-A30BE971-2B33-48F0-8A15-49FDB8484071Q26747406-57452807-870E-49F5-8CEA-22AA22759FBFQ27004287-ED9BA188-4A0E-40E2-BA7C-5C513FD3C6C8Q27023916-87C2D20D-E362-4D42-87C0-6B219148D4E9Q27341851-7C2FC3D5-8E68-40B2-B3B5-2633AE51A69BQ28076811-C4A15225-8740-4535-A1FF-0A7068668A12Q28115076-CBAA05B8-5219-49C7-BE2D-50C38ED6492CQ28116138-4878EDFD-21A1-47D6-9B8A-65A271187312Q28117267-35172010-2A37-4F5B-9142-859F3236DBD8Q28117272-F12320D7-96B5-418F-AC81-4EF2476EB988Q28118107-41833E08-8DB0-464E-8F74-DB0481FD471EQ28118675-5B5021CC-5025-4717-8C7B-E6648C9333CEQ28243779-782DDA9E-A5CF-4892-A335-F09EB7B00067Q28505723-F920BF4A-30B3-4E06-A23E-336D61F668FCQ28506698-845AB242-6176-443F-A88C-07581886F140Q28512063-FCA8D605-9948-4293-8D3F-76313919250AQ30230753-3448CFD0-F400-414D-A37D-4E0306E417A4Q30230906-328609CB-0A26-4996-9882-C1B7F47F58CBQ30433361-2B1337A6-A41A-4FD7-96DF-C61197B4ECAEQ30438742-2D804FBC-8164-49F1-A83A-CADEED06425DQ30441689-0E699A40-D9FD-4A7D-8B53-BF9F670E8A45Q30445072-0B8DCAE9-9E51-47AE-A573-9AFB29DC4B91Q30480964-2698ED05-C518-4247-82CD-36B949BB14C8Q33226407-36F1F79C-F14E-42CF-9906-440BD10B4EF1Q33306700-F8050078-9115-43DD-822D-4570237D8860Q33309340-EFA078A7-7D5E-4C32-B351-EF655B9DCB4EQ33623712-9E17A7F2-4DFC-45D6-AB68-9A787A2D21E5Q33636430-31D2B211-17FD-40B3-BDE8-C00F6AE357CBQ33731727-758455DD-AF4C-4D6B-AF4B-E0F337AE595AQ33748220-5F8B8170-7481-4C42-9B60-D9FB85D45886Q33881972-6683F8F7-1DE9-4E04-A574-C8E0A6DF9CA6
P2860
MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 binding
description
2004 nî lūn-bûn
@nan
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
MAPKAP kinase 2 phosphorylates ...... te required for 14-3-3 binding
@ast
MAPKAP kinase 2 phosphorylates ...... te required for 14-3-3 binding
@en
MAPKAP kinase 2 phosphorylates ...... te required for 14-3-3 binding
@en-gb
MAPKAP kinase 2 phosphorylates ...... te required for 14-3-3 binding
@nl
type
label
MAPKAP kinase 2 phosphorylates ...... te required for 14-3-3 binding
@ast
MAPKAP kinase 2 phosphorylates ...... te required for 14-3-3 binding
@en
MAPKAP kinase 2 phosphorylates ...... te required for 14-3-3 binding
@en-gb
MAPKAP kinase 2 phosphorylates ...... te required for 14-3-3 binding
@nl
prefLabel
MAPKAP kinase 2 phosphorylates ...... te required for 14-3-3 binding
@ast
MAPKAP kinase 2 phosphorylates ...... te required for 14-3-3 binding
@en
MAPKAP kinase 2 phosphorylates ...... te required for 14-3-3 binding
@en-gb
MAPKAP kinase 2 phosphorylates ...... te required for 14-3-3 binding
@nl
P2093
P2860
P3181
P356
P1476
MAPKAP kinase 2 phosphorylates ...... te required for 14-3-3 binding
@en
P2093
Carol A Chrestensen
Donald F Hunt
Jared W Pelo
Mark T Worthington
Melanie J Schroeder
Thomas W Sturgill
P2860
P304
P3181
P356
10.1074/JBC.M310486200
P407
P577
2004-03-12T00:00:00Z