MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine
about
Pharmacogenetics of human ABC transporter ABCC11: new insights into apocrine gland growth and metabolite secretionLocalization of putative binding sites for cyclic guanosine monophosphate and the anti-cancer drug 5-fluoro-2'-deoxyuridine-5'-monophosphate on ABCC11 in silico modelsLocalization of multidrug resistance-associated proteins along the blood-testis barrier in rat, macaque, and human testisMultidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseasesMultidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferationOrganic anion transporter 2 (SLC22A7) is a facilitative transporter of cGMPDependence of multidrug resistance protein-mediated cyclic nucleotide efflux on the background sodium conductanceThe reversal of antineoplastic drug resistance in cancer cells by β-elemeneFOLFOX/FOLFIRI pharmacogenetics: the call for a personalized approach in colorectal cancer therapyMultidrug Resistance Proteins (MRPs) and Cancer TherapyNew perspectives in signaling mediated by receptors coupled to stimulatory G protein: the emerging significance of cAMP efflux and extracellular cAMP-adenosine pathwayRegulation of the Axillary Osmidrosis-Associated ABCC11 Protein Stability by N-Linked Glycosylation: Effect of Glucose ConditionTargeting multidrug resistance in cancerCardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Pharmacological considerations for tenofovir and emtricitabine to prevent HIV infectionHydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs.Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters.Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation.Schistosome ABC multidrug transporters: From pharmacology to physiology.Activity of the multikinase inhibitor sorafenib in combination with cytarabine in acute myeloid leukemia.The role of nucleoside/nucleotide transport and metabolism in the uptake and retention of 3'-fluoro-3'-deoxythymidine in human B-lymphoblast cells.The MRP family of drug efflux pumps.Nucleoside transporters in chronic lymphocytic leukaemia.MRP8/ABCC11 expression is regulated by dexamethasone in breast cancer cells and is associated to progesterone receptor status in breast tumors.Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes.Pharmacogenomics of human ABC transporter ABCC11 (MRP8): potential risk of breast cancer and chemotherapy failureTyrosine kinase inhibitors as modulators of ABC transporter-mediated drug resistance.3'-deoxy-3'-[18F]fluorothymidine positron emission tomography for response assessment in soft tissue sarcoma: a pilot study to correlate imaging findings with tissue thymidine kinase 1 and Ki-67 activity and histopathologic response.Function and regulation of multidrug resistance proteins (MRPs) in the renal elimination of organic anions.Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins.Use of in vitro transporter assays to understand hepatic and renal disposition of new drug candidates.Metabolism of ATP-binding cassette drug transporter inhibitors: complicating factor for multidrug resistance.High expression of ATP-binding cassette transporter ABCC11 in breast tumors is associated with aggressive subtypes and low disease-free survivalRedox regulation of multidrug resistance in cancer chemotherapy: molecular mechanisms and therapeutic opportunitiesResistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1Defining targets for investigating the pharmacogenomics of adverse drug reactions to antifungal agents.Targeting the chromatin remodeling enzyme BRG1 increases the efficacy of chemotherapy drugs in breast cancer cellsHuman multidrug resistance protein 7 (ABCC10) is a resistance factor for nucleoside analogues and epothilone B.Disruption of cAMP and prostaglandin E2 transport by multidrug resistance protein 4 deficiency alters cAMP-mediated signaling and nociceptive response.
P2860
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P2860
MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
name
MRP8, ATP-binding cassette C11 ...... phosphonylmethoxyethyl)adenine
@ast
MRP8, ATP-binding cassette C11 ...... phosphonylmethoxyethyl)adenine
@en
MRP8, ATP-binding cassette C11 ...... phosphonylmethoxyethyl)adenine
@en-gb
MRP8, ATP-binding cassette C11 ...... phosphonylmethoxyethyl)adenine
@nl
type
label
MRP8, ATP-binding cassette C11 ...... phosphonylmethoxyethyl)adenine
@ast
MRP8, ATP-binding cassette C11 ...... phosphonylmethoxyethyl)adenine
@en
MRP8, ATP-binding cassette C11 ...... phosphonylmethoxyethyl)adenine
@en-gb
MRP8, ATP-binding cassette C11 ...... phosphonylmethoxyethyl)adenine
@nl
prefLabel
MRP8, ATP-binding cassette C11 ...... phosphonylmethoxyethyl)adenine
@ast
MRP8, ATP-binding cassette C11 ...... phosphonylmethoxyethyl)adenine
@en
MRP8, ATP-binding cassette C11 ...... phosphonylmethoxyethyl)adenine
@en-gb
MRP8, ATP-binding cassette C11 ...... phosphonylmethoxyethyl)adenine
@nl
P2093
P3181
P356
P1476
MRP8, ATP-binding cassette C11 ...... phosphonylmethoxyethyl)adenine
@en
P2093
Elena Kotova
Elizabeth Hopper-Borge
Gary D Kruh
Martin G Belinsky
Yanping Guo
Zhe-Sheng Chen
P304
P3181
P356
10.1074/JBC.M304059200
P407
P577
2003-08-08T00:00:00Z