Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung - Wikidata - wikimedia - TriplyDB

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

http://www.wikidata.org/entity/Q24303485

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Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities.Alveolar development and disease Pulmonary adenocarcinoma with mucin production modulates phenotype according to common genetic traits: a reappraisal of mucinous adenocarcinoma and colloid adenocarcinoma Thyroid transcription factor-1-regulated microRNA-532-5p targets KRAS and MKL2 oncogenes and induces apoptosis in lung adenocarcinoma cells Pulmonary macrophage transplantation therapy Epidermal growth factor receptor (EGFR) mutations are exceptionally rare in thyroid transcription factor (TTF-1)-negative adenocarcinomas of the lung.Proceedings of the 2014 National Toxicology Program Satellite Symposium Transcription factor and microRNA interactions in lung cells: an inhibitory link between NK2 homeobox 1, miR-200c and the developmental and oncogenic factors Nfib and Myb.Integrative Genomics Implicates EGFR as a Downstream Mediator in NKX2-1 Amplified Non-Small Cell Lung Cancer.SINCERA: A Pipeline for Single-Cell RNA-Seq Profiling Analysis Lung cancer in the era of precision medicine A favourable prognostic marker for EGFR mutant non-small cell lung cancer: immunohistochemical analysis of MUC5B.NKX2-1-mediated p53 expression modulates lung adenocarcinoma progression via modulating IKKβ/NF-κB activation.PTCSC3 Is Involved in Papillary Thyroid Carcinoma Development by Modulating S100A4 Gene Expression.The development and plasticity of alveolar type 1 cells.SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma.Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target.How do K-RAS-activated cells evade cellular defense mechanisms?Thyroid Transcription Factor 1 Reprograms Angiogenic Activities of Secretome.MicroRNA-33a mediates the regulation of high mobility group AT-hook 2 gene (HMGA2) by thyroid transcription factor 1 (TTF-1/NKX2-1)Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasis Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.Tight junction proteins: from barrier to tumorigenesis.The complexity of thyroid transcription factor 1 with both pro- and anti-oncogenic activities Lung Cancer with Diffuse Ground-glass Shadow in Two Lungs and Respiratory Failure.Activated K-RAS and its effect on morphological appearance.Lineage factors and differentiation states in lung cancer progression.Keeping it together: Pulmonary alveoli are maintained by a hierarchy of cellular programs.Characterization of V-set and immunoglobulin domain containing 1 exerting a tumor suppressor function in gastric, lung, and esophageal cancer cells.Long and short noncoding RNAs in lung cancer precision medicine: Opportunities and challenges.ERBB3-independent activation of the PI3K pathway in EGFR-mutant lung adenocarcinomas Distinct prognostic roles and heterogeneity of TTF1 copy number and TTF1 protein expression in non-small cell lung cancer.Developmental transcription factor NFIB is a putative target of oncofetal miRNAs and is associated with tumour aggressiveness in lung adenocarcinoma.Inactivating mutations and hypermethylation of the NKX2-1/TTF-1 gene in non-terminal respiratory unit-type lung adenocarcinomas.Gene signature driving invasive mucinous adenocarcinoma of the lung.Hopping between differentiation states in lung adenocarcinoma.Biology of invasive mucinous adenocarcinoma of the lung.The role of Thyroid Transcription Factor-1 and Tumor differentiation in Resected Lung Adenocarcinoma.TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.FOXM1 activates AGR2 and causes progression of lung adenomas into invasive mucinous adenocarcinomas.

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Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

http://www.wikidata.org/entity/Q24303485

description

2012 nî lūn-bûn

@nan

2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

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2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

@ast

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

@en

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

@en-gb

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

@nl

type

label

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

@ast

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

@en

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

@en-gb

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

@nl

prefLabel

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

@ast

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

@en

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

@en-gb

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

@nl

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Journal of Clinical Investigation

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Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

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Angela R Keiser

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David H Tompkins

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Haiping Hao

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Jeffrey A Whitsett

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Lingling Du

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Michael L Mucenski

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Takeshi Nagayasu

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Takuya Fukazawa

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Yan Xu

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Yoshio Naomoto

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P2860

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis

Thyroid transcription factor in differentiating type II cells: regulation, isoforms, and target genes

NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma

Thyroid transcription factor-1 inhibits transforming growth factor-beta-mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells

Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer

Characterizing the cancer genome in lung adenocarcinoma.

Oncogenic cooperation and coamplification of developmental transcription factor genes in lung cancer

SPDEF regulates goblet cell hyperplasia in the airway epithelium

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers.

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10.1172/JCI64048

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12

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122

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23143308

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haploinsufficiency

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3533546

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