Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase
about
HOXA9 methylation by PRMT5 is essential for endothelial cell expression of leukocyte adhesion moleculesArginine methylation controls growth regulation by E2F-1Phosphorylation-dependent regulation of SCF(Fbx4) dimerization and activity involves a novel component, 14-3-3ɛNovel Molecular Markers for Breast CancerTargeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsMechanisms of epigenetic regulation of leukemia onset and progressionCrystal structure of the human PRMT5:MEP50 complexStructure of the Arginine Methyltransferase PRMT5-MEP50 Reveals a Mechanism for Substrate SpecificityA selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL modelsTargeting the cyclin-dependent kinases (CDK) 4/6 in estrogen receptor-positive breast cancersThe PRMT5 arginine methyltransferase: many roles in development, cancer and beyondCyclin D as a therapeutic target in cancerThe Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformationProtein arginine methyltransferase Prmt5-Mep50 methylates histones H2A and H4 and the histone chaperone nucleoplasmin in Xenopus laevis eggsCRL4Cdt2: master coordinator of cell cycle progression and genome stabilityInterplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis.Expression of PRMT5 correlates with malignant grade in gliomas and plays a pivotal role in tumor growth in vitro.Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome.MicroRNA-520b inhibits growth of hepatoma cells by targeting MEKK2 and cyclin D1.New roles of cyclin D1.Non-canonical CRL4A/4B(CDT2) interacts with RAD18 to modulate post replication repair and cell survival.PRMT5 is upregulated in malignant and metastatic melanoma and regulates expression of MITF and p27(Kip1.).PIM kinase inhibitor AZD1208 for treatment of MYC-driven prostate cancerCell biological regulation of division fate in vertebrate neuroepithelial cells.Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferaseSelective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformationVersatility of PRMT5-induced methylation in growth control and development.MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition.Methylosome Protein 50 and PKCδ/p38δ Protein Signaling Control Keratinocyte Proliferation via Opposing Effects on p21Cip1 Gene ExpressionMolecular pathogenesis of mantle cell lymphoma.Pinellia pedatisecta agglutinin interacts with the methylosome and induces cancer cell death.PRMT5 Is Upregulated in HTLV-1-Mediated T-Cell Transformation and Selective Inhibition Alters Viral Gene Expression and Infected Cell Survival.Overexpression of PRMT5 promotes tumor cell growth and is associated with poor disease prognosis in epithelial ovarian cancer.CDK4: A Key Player in the Cell Cycle, Development, and CancerNon-canonical functions of cell cycle cyclins and cyclin-dependent kinases.Promoter-enhancer looping at the PPARγ2 locus during adipogenic differentiation requires the Prmt5 methyltransferase.PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB.Protein arginine methyltransferase 5 regulates multiple signaling pathways to promote lung cancer cell proliferationMediator complex recruits epigenetic regulators via its two cyclin-dependent kinase subunits to repress transcription of immune response genesAutomethylation of protein arginine methyltransferase 8 (PRMT8) regulates activity by impeding S-adenosylmethionine sensitivity
P2860
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P2860
Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Nuclear cyclin D1/CDK4 kinase ...... of the PRMT5 methyltransferase
@ast
Nuclear cyclin D1/CDK4 kinase ...... of the PRMT5 methyltransferase
@en
Nuclear cyclin D1/CDK4 kinase ...... of the PRMT5 methyltransferase
@en-gb
Nuclear cyclin D1/CDK4 kinase ...... of the PRMT5 methyltransferase
@nl
type
label
Nuclear cyclin D1/CDK4 kinase ...... of the PRMT5 methyltransferase
@ast
Nuclear cyclin D1/CDK4 kinase ...... of the PRMT5 methyltransferase
@en
Nuclear cyclin D1/CDK4 kinase ...... of the PRMT5 methyltransferase
@en-gb
Nuclear cyclin D1/CDK4 kinase ...... of the PRMT5 methyltransferase
@nl
prefLabel
Nuclear cyclin D1/CDK4 kinase ...... of the PRMT5 methyltransferase
@ast
Nuclear cyclin D1/CDK4 kinase ...... of the PRMT5 methyltransferase
@en
Nuclear cyclin D1/CDK4 kinase ...... of the PRMT5 methyltransferase
@en-gb
Nuclear cyclin D1/CDK4 kinase ...... of the PRMT5 methyltransferase
@nl
P2093
P2860
P921
P3181
P1433
P1476
Nuclear cyclin D1/CDK4 kinase ...... of the PRMT5 methyltransferase
@en
P2093
Anil K Rustgi
Buddha Gurung
Hestia Mellert
Hiroshi Nakagawa
J Alan Diehl
Jong Kyong Kim
Laura Pontano Vaites
Priya Aggarwal
Steven B McMahon
Xianxin Hua
P2860
P304
P3181
P356
10.1016/J.CCR.2010.08.012
P407
P577
2010-10-19T00:00:00Z