PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling.
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NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligandsPhosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targetsLoss of PTEN binding adapter protein NHERF1 from plasma membrane in glioblastoma contributes to PTEN inactivationNHERF1/EBP50 controls morphogenesis of 3D colonic glands by stabilizing PTEN and ezrin-radixin-moesin proteins at the apical membraneThe scaffolding protein EBP50 regulates microvillar assembly in a phosphorylation-dependent mannerBreast cancer-derived K172N, D301V mutations abolish Na+/H+ exchanger regulatory factor 1 inhibition of platelet-derived growth factor receptor signalingProtein kinases and phosphatases in the control of cell fateNetwork of Cancer Genes: a web resource to analyze duplicability, orthology and network properties of cancer genesPhosphatase and Tensin Homologue: Novel Regulation by Developmental SignalingStructural and functional properties of platelet-derived growth factor and stem cell factor receptorsRegulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factorsPTEN modulators: a patent reviewTurning off AKT: PHLPP as a drug targetNHERF1/EBP50 and NF2 as diagnostic markers for choroid plexus tumors.Structural Insights into Neutrophilic Migration Revealed by the Crystal Structure of the Chemokine Receptor CXCR2 in Complex with the First PDZ Domain of NHERF1PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastomaThe Role of PTEN in Tumor AngiogenesisComputational modeling and analysis of insulin induced eukaryotic translation initiationPar-3-mediated junctional localization of the lipid phosphatase PTEN is required for cell polarity establishmentNa+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cellsEBP50 is involved in the regulation of vascular smooth muscle cell migration and cytokinesis.Role of platelet-derived growth factors in physiology and medicineDirect positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase.NHERF1/EBP50 is an organizer of polarity structures and a diagnostic marker in ependymomaReactive oxygen species mediate mitogenic growth factor signaling pathways in human leiomyoma smooth muscle cellsInvasive glioblastoma cells acquire stemness and increased Akt activation.Targeted disruption of ephrin B1 in cells of myeloid lineage increases osteoclast differentiation and bone resorption in mice.PTEN Tumor Suppressor Network in PI3K-Akt Pathway ControlA new role for PTEN in regulating transient receptor potential canonical channel 6-mediated Ca2+ entry, endothelial permeability, and angiogenesis.NHERF1/EBP50 is a new marker in colorectal cancer.Alterations in the proteome of the NHERF1 knockout mouse jejunal brush border membrane vesiclesApoptosis regulator through modulating IAP expression (ARIA) controls the PI3K/Akt pathway in endothelial and endothelial progenitor cells.Alterations in the proteome of the NHERF2 knockout mouse jejunal brush border membrane vesicles.E6 and E7 from human papillomavirus type 16 cooperate to target the PDZ protein Na/H exchange regulatory factor 1.Apical membrane segregation of phosphatidylinositol-4,5-bisphosphate influences parathyroid hormone 1 receptor compartmental signaling and localization via direct regulation of ezrin in LLC-PK1 cellsNHERFs, NEP, MAGUKs, and more: interactions that regulate PTEN.The scaffolding protein EBP50 promotes vascular smooth muscle cell proliferation and neointima formation by regulating Skp2 and p21(cip1).Suppression of breast cancer cell growth by Na+/H+ exchanger regulatory factor 1 (NHERF1)Aberrant nuclear localization of EBP50 promotes colorectal carcinogenesis in xenotransplanted mice by modulating TCF-1 and β-catenin interactions.Phosphorylation of EBP50 negatively regulates β-PIX-dependent Rac1 activity in anoikis.
P2860
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P248
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P2860
PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling.
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling
@nl
PTEN tumor suppressor associat ...... nuate PDGF receptor signaling.
@ast
PTEN tumor suppressor associat ...... nuate PDGF receptor signaling.
@en
PTEN tumor suppressor associat ...... nuate PDGF receptor signaling.
@en-gb
type
label
PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling
@nl
PTEN tumor suppressor associat ...... nuate PDGF receptor signaling.
@ast
PTEN tumor suppressor associat ...... nuate PDGF receptor signaling.
@en
PTEN tumor suppressor associat ...... nuate PDGF receptor signaling.
@en-gb
prefLabel
PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling
@nl
PTEN tumor suppressor associat ...... nuate PDGF receptor signaling.
@ast
PTEN tumor suppressor associat ...... nuate PDGF receptor signaling.
@en
PTEN tumor suppressor associat ...... nuate PDGF receptor signaling.
@en-gb
P2093
P2860
P921
P3181
P356
P1433
P1476
PTEN tumor suppressor associat ...... nuate PDGF receptor signaling.
@en
P2093
Erica L Kreimann
Fabiana C Morales
Maria-Magdalena Georgescu
Yoko Takahashi
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7600979
P407
P577
2006-02-02T00:00:00Z