Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization - Wikidata - wikimedia - TriplyDB

Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization

Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization

http://www.wikidata.org/entity/Q24303653

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The individual N- and C-lobes of calmodulin tether to the Cav1.2 channel and rescue the channel activity from run-down in ventricular myocytes of guinea-pig heart Calmodulin regulation (calmodulation) of voltage-gated calcium channels L-type calcium channel targeting and local signalling in cardiac myocytes Towards a Unified Theory of Calmodulin Regulation (Calmodulation) of Voltage-Gated Calcium and Sodium Channels Crystallographic basis for calcium regulation of sodium channels Allosteric mechanism of water-channel gating by Ca2+–calmodulin Progress in the structural understanding of voltage-gated calcium channel (CaV) function and modulation.Applications of isothermal titration calorimetry in pure and applied research--survey of the literature from 2010.Calcium channel auxiliary α2δ and β subunits: trafficking and one step beyond.Calmodulin overexpression does not alter Cav1.2 function or oligomerization state.Calpastatin domain L is a partial agonist of the calmodulin-binding site for channel activation in Cav1.2 Ca2+ channels.Ca2+ signaling amplification by oligomerization of L-type Cav1.2 channels.Structural insights into neuronal K+ channel-calmodulin complexes.Competitive and non-competitive regulation of calcium-dependent inactivation in CaV1.2 L-type Ca2+ channels by calmodulin and Ca2+-binding protein 1 Ca(2+) entry into neurons is facilitated by cooperative gating of clustered CaV1.3 channels.What can naturally occurring mutations tell us about Ca(v)1.x channel function?Voltage-gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacology Apo states of calmodulin and CaBP1 control CaV1 voltage-gated calcium channel function through direct competition for the IQ domain.Calcium-dependent stoichiometries of the KCa2.2 (SK) intracellular domain/calmodulin complex in solution.L-type calcium channel auto-regulation of transcription.Trafficking and stability of voltage-gated calcium channels.Seeing the forest through the trees: towards a unified view on physiological calcium regulation of voltage-gated sodium channels.Structural diversity of calmodulin binding to its target sites.Structural analysis of calmodulin binding to ion channels demonstrates the role of its plasticity in regulation.Calmodulin in a heartbeat.Deciphering the subunit composition of multimeric proteins by counting photobleaching steps.A novel calmodulin site in the Cav1.2 N-terminus regulates calcium-dependent inactivation.Effect of the Brugada syndrome mutation A39V on calmodulin regulation of Cav1.2 channels.Interactions between N and C termini of α1C subunit regulate inactivation of CaV1.2 L-type Ca(2+) channel.The motif of human cardiac myosin-binding protein C is required for its Ca2+-dependent interaction with calmodulin Apocalmodulin itself promotes ion channel opening and Ca(2+) regulation.Pivoting between calmodulin lobes triggered by calcium in the Kv7.2/calmodulin complex.Dynamic switching of calmodulin interactions underlies Ca2+ regulation of CaV1.3 channels.Thermodynamic linkage between calmodulin domains binding calcium and contiguous sites in the C-terminal tail of Ca(V)1.2.Detecting stoichiometry of macromolecular complexes in live cells using FRET.Structural analyses of Ca²⁺/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation.Molecular moieties masking Ca2+-dependent facilitation of voltage-gated Cav2.2 Ca2+ channels.Bilobal architecture is a requirement for calmodulin signaling to CaV1.3 channels.Multiple C-terminal tail Ca2+/CaMs regulate CaV1.2 function but do not mediate channel dimerization.

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Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization

http://www.wikidata.org/entity/Q24303653

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Multiple C-terminal tail Ca(2+ ...... t mediate channel dimerization

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Multiple C-terminal tail Ca(2+ ...... t mediate channel dimerization

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Multiple C-terminal tail Ca(2+ ...... t mediate channel dimerization

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Multiple C-terminal tail Ca(2+ ...... t mediate channel dimerization

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type

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Multiple C-terminal tail Ca(2+ ...... t mediate channel dimerization

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Multiple C-terminal tail Ca(2+ ...... t mediate channel dimerization

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Multiple C-terminal tail Ca(2+ ...... t mediate channel dimerization

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Multiple C-terminal tail Ca(2+ ...... t mediate channel dimerization

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Multiple C-terminal tail Ca(2+ ...... t mediate channel dimerization

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Multiple C-terminal tail Ca(2+ ...... t mediate channel dimerization

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Multiple C-terminal tail Ca(2+ ...... t mediate channel dimerization

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Multiple C-terminal tail Ca(2+ ...... t mediate channel dimerization

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The EMBO Journal

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Multiple C-terminal tail Ca(2+ ...... t mediate channel dimerization

@en

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Christine H Rumpf

http://www.w3.org/2001/XMLSchema#string

Daniel L Minor

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Ehud Y Isacoff

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Elizabeth S Cooley

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Eun Young Kim

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Felix Findeisen

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Ryan J Arant

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Orientation of the calcium channel beta relative to the alpha(1)2.2 subunit is critical for its regulation of channel activity

Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5

Crystal structure of apo-calmodulin bound to the first two IQ motifs of myosin V reveals essential recognition features

Structural and molecular basis of the assembly of the TRPP2/PKD1 complex

The NMDA Receptor NR1 C1 Region Bound to Calmodulin: Structural Insights into Functional Differences between Homologous Domains

Structures of CaV2 Ca2+/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation

Solution Structure of the NaV1.2 C-terminal EF-hand Domain

Crystal structure of dimeric cardiac L-type calcium channel regulatory domains bridged by Ca2+* calmodulins

Coot: model-building tools for molecular graphics

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

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3924-3938

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scholarly article

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1596220

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10.1038/EMBOJ.2010.260

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23

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29

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Filip Van Petegem

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2010-10-15T00:00:00Z

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47450437

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20953164

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3020648

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