Coordination of DNA damage responses via the Smc5/Smc6 complex
about
Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaksIdentification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complexComposition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complexHuman MMS21/NSE2 is a SUMO ligase required for DNA repairQri2/Nse4, a component of the essential Smc5/6 DNA repair complex.H2A.Z-dependent regulation of cohesin dynamics on chromosome armsSmc5/6 maintains stalled replication forks in a recombination-competent conformation.Transformation/transcription domain-associated protein (TRRAP)-mediated regulation of Wee1Sumoylation: a new wrestler in the DNA repair ringInitiation of DNA damage responses through XPG-related nucleasesSmc5p promotes faithful chromosome transmission and DNA repair in Saccharomyces cerevisiae.Brc1-mediated DNA repair and damage toleranceThe Smc5/Smc6/MAGE complex confers resistance to caffeine and genotoxic stress in Drosophila melanogaster.Smc5/6-Mms21 prevents and eliminates inappropriate recombination intermediates in meiosis.Roles of vertebrate Smc5 in sister chromatid cohesion and homologous recombinational repair.Nse1-dependent recruitment of Smc5/6 to lesion-containing loci contributes to the repair defects of mutant complexesSex comb on midleg (Scm) is a functional link between PcG-repressive complexes in DrosophilaBrc1-mediated rescue of Smc5/6 deficiency: requirement for multiple nucleases and a novel Rad18 functionMms22 preserves genomic integrity during DNA replication in Schizosaccharomyces pombe.Gene Expression Differences in Peripheral Blood of Parkinson's Disease Patients with Distinct Progression ProfilesSMC complexes in bacterial chromosome condensation and segregation.Meiotic DNA joint molecule resolution depends on Nse5-Nse6 of the Smc5-Smc6 holocomplexRegulation of Chk1 by its C-terminal domain.DNA damage checkpoint and recombinational repair differentially affect the replication stress tolerance of Smc6 mutants.Regulation of chk1.Smc5/6-mediated regulation of replication progression contributes to chromosome assembly during mitosis in human cells.An acetyltransferase-independent function of Eso1 regulates centromere cohesion.Rad62 protein functionally and physically associates with the smc5/smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast.Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis.Loss of Caenorhabditis elegans BRCA1 promotes genome stability during replication in smc-5 mutantsFunctional interplay between cohesin and Smc5/6 complexes.Non-SMC Element 2 (NSMCE2) of the SMC5/6 Complex Helps to Resolve Topological Stress.Rhp51-dependent recombination intermediates that do not generate checkpoint signal are accumulated in Schizosaccharomyces pombe rad60 and smc5/6 mutants after release from replication arrest.Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage.Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1.Nse1 and Nse4, subunits of the Smc5-Smc6 complex, are involved in Dictyostelium development upon starvation.Smc5/6 is required for repair at collapsed replication forksLocalization of Smc5/6 to centromeres and telomeres requires heterochromatin and SUMO, respectively.The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complexSmc5-Smc6-dependent removal of cohesin from mitotic chromosomes.
P2860
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P2860
Coordination of DNA damage responses via the Smc5/Smc6 complex
description
2004 nî lūn-bûn
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2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2004 թվականի հունվարին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年论文
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Coordination of DNA damage responses via the Smc5/Smc6 complex
@ast
Coordination of DNA damage responses via the Smc5/Smc6 complex
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Coordination of DNA damage responses via the Smc5/Smc6 complex
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Coordination of DNA damage responses via the Smc5/Smc6 complex
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Coordination of DNA damage responses via the Smc5/Smc6 complex
@ast
Coordination of DNA damage responses via the Smc5/Smc6 complex
@en
Coordination of DNA damage responses via the Smc5/Smc6 complex
@en-gb
Coordination of DNA damage responses via the Smc5/Smc6 complex
@nl
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Coordination of DNA damage responses via the Smc5/Smc6 complex
@ast
Coordination of DNA damage responses via the Smc5/Smc6 complex
@en
Coordination of DNA damage responses via the Smc5/Smc6 complex
@en-gb
Coordination of DNA damage responses via the Smc5/Smc6 complex
@nl
P2093
P2860
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P1476
Coordination of DNA damage responses via the Smc5/Smc6 complex
@en
P2093
Andrew R Cuddihy
Daniel M Sheedy
Matthew J O'Connell
Susan H Harvey
P2860
P304
P3181
P356
10.1128/MCB.24.2.662-674.2004
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P577
2004-01-01T00:00:00Z