Antagonistic effects of beta-site amyloid precursor protein-cleaving enzymes 1 and 2 on beta-amyloid peptide production in cells
about
BACE1 and presenilin: two unusual aspartyl proteases involved in Alzheimer's diseaseTrafficking and proteolytic processing of APPBACE1 expression and activity: relevance in Alzheimer's diseaseAsynchronous evolutionary origins of Aβ and BACE1Targeting the γ-/β-secretase interaction reduces β-amyloid generation and ameliorates Alzheimer's disease-related pathogenesisBACE1 and BACE2 enzymatic activities in Alzheimer's disease.Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects.Evaluation of BACE1 Silencing in Cellular ModelsBeta-secretase: structure, function, and evolution.Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process.Targeting the β secretase BACE1 for Alzheimer's disease therapy.Nav1.7 protein and mRNA expression in the dorsal root ganglia of rats with chronic neuropathic pain.BACE2 expression increases in human neurodegenerative disease.Identification of BACE2 as an avid ß-amyloid-degrading proteaseRelevance of amyloid precursor-like protein 2 C-terminal fragments in pancreatic cancer cells.Linking vascular disorders and Alzheimer's disease: potential involvement of BACE1The Alzheimer's disease beta-secretase enzyme, BACE1.The Basic Biology of BACE1: A Key Therapeutic Target for Alzheimer's Disease.Alzheimer's disease and the amyloid-beta peptide.Aspects of beta-amyloid as a biomarker for Alzheimer's disease.Treatment strategies targeting amyloid β-protein.Recent progress in the drug discovery of non-peptidic BACE1 inhibitors.BACE1 inhibitor drugs in clinical trials for Alzheimer's disease.Molecular modeling, synthesis, and activity studies of novel biaryl and fused-ring BACE1 inhibitorsExpression of the Alzheimer protease BACE1 is suppressed via its 5'-untranslated region.Dimerization of beta-site beta-amyloid precursor protein-cleaving enzyme.β-Secretase activity in rat astrocytes: translational block of BACE1 and modulation of BACE2 expression.Efficient inhibition of beta-secretase gene expression in HEK293 cells by tRNAVal-driven and CTE-helicase associated hammerhead ribozymes.BACE1 suppression by RNA interference in primary cortical neurons.Altered beta-secretase enzyme kinetics and levels of both BACE1 and BACE2 in the Alzheimer's disease brain.Nucleic Acid-Based Theranostics for Tackling Alzheimer's Disease.
P2860
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P2860
Antagonistic effects of beta-site amyloid precursor protein-cleaving enzymes 1 and 2 on beta-amyloid peptide production in cells
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Antagonistic effects of beta-s ...... id peptide production in cells
@ast
Antagonistic effects of beta-s ...... id peptide production in cells
@en
Antagonistic effects of beta-s ...... id peptide production in cells
@en-gb
Antagonistic effects of beta-s ...... id peptide production in cells
@nl
type
label
Antagonistic effects of beta-s ...... id peptide production in cells
@ast
Antagonistic effects of beta-s ...... id peptide production in cells
@en
Antagonistic effects of beta-s ...... id peptide production in cells
@en-gb
Antagonistic effects of beta-s ...... id peptide production in cells
@nl
prefLabel
Antagonistic effects of beta-s ...... id peptide production in cells
@ast
Antagonistic effects of beta-s ...... id peptide production in cells
@en
Antagonistic effects of beta-s ...... id peptide production in cells
@en-gb
Antagonistic effects of beta-s ...... id peptide production in cells
@nl
P2093
P356
P1476
Antagonistic effects of beta-s ...... id peptide production in cells
@en
P2093
Grace Gordon
Guriqbal Basi
Lisa McConlogue
Michelle Zeller
Normand Frigon
Robin Barbour
Sukanto Sinha
P304
P356
10.1074/JBC.M300169200
P407
P577
2003-08-22T00:00:00Z