The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function
about
The UBX protein SAKS1 negatively regulates endoplasmic reticulum-associated degradation and p97-dependent degradationMass Spectrometry-Based Proteomics for Investigating DNA Damage-Associated Protein UbiquitylationUBXD Proteins: A Family of Proteins with Diverse Functions in CancerBRCA1 targets G2/M cell cycle proteins for ubiquitination and proteasomal degradationSubstitution of aspartic acid with glutamic acid at position 67 of the BRCA1 RING domain retains ubiquitin ligase activity and zinc(II) binding with a reduced transition temperature.Diversity in genetic in vivo methods for protein-protein interaction studies: from the yeast two-hybrid system to the mammalian split-luciferase system.In Vitro Enhanced Sensitivity to Cisplatin in D67Y BRCA1 RING Domain Protein.Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signalingMultiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα.A plant alkaloid, veratridine, potentiates cancer chemosensitivity by UBXN2A-dependent inhibition of an oncoprotein, mortalin-2.Linkage-specific conformational ensembles of non-canonical polyubiquitin chainsLinkage via K27 Bestows Ubiquitin Chains with Unique Properties among Polyubiquitins.Unraveling the complexity of ubiquitin signalingUBXN1 interferes with Rig-I-like receptor-mediated antiviral immune response by targeting MAVS.Novel protein interactions with endoglin and activin receptor-like kinase 1: potential role in vascular networks.The BRCA1 ubiquitin ligase and homologous recombination repair.Discovery of Mdm2-MdmX E3 ligase inhibitors using a cell-based ubiquitination assay.The AAA+ ATPase p97, a cellular multitool.The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by the platinum-based anticancer drugs.mRNA Processing Factor CstF-50 and Ubiquitin Escort Factor p97 Are BRCA1/BARD1 Cofactors Involved in Chromatin Remodeling during the DNA Damage Response.Key genes and regulatory networks involved in the initiation, progression and invasion of colorectal cancer.Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.Possible role of the Nipah virus V protein in the regulation of the interferon beta induction by interacting with UBX domain-containing protein1.Network-based analysis of oligodendrogliomas predicts novel cancer gene candidates within the region of the 1p/19q co-deletion.A new bioinformatics tool to help assess the significance of BRCA1 variants.
P2860
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P2860
The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function
description
2010 nî lūn-bûn
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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The UBXN1 protein associates w ...... nhibits its enzymatic function
@ast
The UBXN1 protein associates w ...... nhibits its enzymatic function
@en
The UBXN1 protein associates w ...... nhibits its enzymatic function
@en-gb
The UBXN1 protein associates w ...... nhibits its enzymatic function
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type
label
The UBXN1 protein associates w ...... nhibits its enzymatic function
@ast
The UBXN1 protein associates w ...... nhibits its enzymatic function
@en
The UBXN1 protein associates w ...... nhibits its enzymatic function
@en-gb
The UBXN1 protein associates w ...... nhibits its enzymatic function
@nl
prefLabel
The UBXN1 protein associates w ...... nhibits its enzymatic function
@ast
The UBXN1 protein associates w ...... nhibits its enzymatic function
@en
The UBXN1 protein associates w ...... nhibits its enzymatic function
@en-gb
The UBXN1 protein associates w ...... nhibits its enzymatic function
@nl
P2093
P2860
P921
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The UBXN1 protein associates w ...... nhibits its enzymatic function
@en
P2093
Foon Wu-Baer
Richard Baer
Thomas Ludwig
P2860
P304
P3181
P356
10.1128/MCB.01056-09
P407
P577
2010-06-01T00:00:00Z