Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
about
I SA channel complexes include four subunits each of DPP6 and Kv4.2Multiprotein assembly of Kv4.2, KChIP3 and DPP10 produces ternary channel complexes with ISA-like propertiesKv4.2 and accessory dipeptidyl peptidase-like protein 10 (DPP10) subunit preferentially form a 4:2 (Kv4.2:DPP10) channel complexIon channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac deathS-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivationAugmentation of Kv4.2-encoded currents by accessory dipeptidyl peptidase 6 and 10 subunits reflects selective cell surface Kv4.2 protein stabilizationDipeptidyl peptidase-like protein 6 is required for normal electrophysiological properties of cerebellar granule cellsLocalization and targeting of voltage-dependent ion channels in mammalian central neurons.Molecular determinants of cardiac transient outward potassium current (I(to)) expression and regulationA novel DPP6 isoform (DPP6-E) can account for differences between neuronal and reconstituted A-type K(+) channels.Incorporation of DPP6a and DPP6K variants in ternary Kv4 channel complex reconstitutes properties of A-type K current in rat cerebellar granule cells.DPP6 domains responsible for its localization and function.DPP10 splice variants are localized in distinct neuronal populations and act to differentially regulate the inactivation properties of Kv4-based ion channelsK(V)4.3 N-terminal deletion mutant Δ2-39: effects on inactivation and recovery characteristics in both the absence and presence of KChIP2b.A new TASK for Dipeptidyl Peptidase-like Protein 6.Mapping and identifying genes for asthma and psoriasisDifferential cycling rates of Kv4.2 channels in proximal and distal dendrites of hippocampal CA1 pyramidal neurons.Transient outward potassium current, 'Ito', phenotypes in the mammalian left ventricle: underlying molecular, cellular and biophysical mechanisms.A dipeptidyl aminopeptidase-like protein remodels gating charge dynamics in Kv4.2 channels.Functionally active t1-t1 interfaces revealed by the accessibility of intracellular thiolate groups in kv4 channelsA role for DPPX modulating external TEA sensitivity of Kv4 channels.A novel N-terminal motif of dipeptidyl peptidase-like proteins produces rapid inactivation of KV4.2 channels by a pore-blocking mechanism.Auxiliary KChIP4a suppresses A-type K+ current through endoplasmic reticulum (ER) retention and promoting closed-state inactivation of Kv4 channelsDistinct cellular distributions of Kv4 pore-forming and auxiliary subunits in rat dorsal root ganglion neurons.Kv4 accessory protein DPPX (DPP6) is a critical regulator of membrane excitability in hippocampal CA1 pyramidal neuronsDPP6 Localization in Brain Supports Function as a Kv4 Channel Associated ProteinMolecular Basis of Functional Myocardial Potassium Channel Diversity.Functional stoichiometry underlying KChIP regulation of Kv4.2 functional expressionThe neuronal Kv4 channel complex.The dipeptidyl-peptidase-like protein DPP6 determines the unitary conductance of neuronal Kv4.2 channels.Potassium channels: newly found players in synaptic plasticity.Multiple intermediate states precede pore block during N-type inactivation of a voltage-gated potassium channel.Weighing the evidence for a ternary protein complex mediating A-type K+ currents in neurons.Dipeptidyl peptidase (DP) 6 and DP10: novel brain proteins implicated in human health and disease.Modulatory mechanisms and multiple functions of somatodendritic A-type K (+) channel auxiliary subunitsDipeptidyl peptidase-IV and related molecules: markers of malignancy?Transient outward potassium channel: a heart failure mediator.NMR analysis of KChIP4a reveals structural basis for control of surface expression of Kv4 channel complexes.The use of automated parameter searches to improve ion channel kinetics for neural modeling.Multiple Kv channel-interacting proteins contain an N-terminal transmembrane domain that regulates Kv4 channel trafficking and gating.
P2860
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P2860
Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
description
2004 nî lūn-bûn
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2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
@ast
Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
@en
Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
@en-gb
Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
@nl
type
label
Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
@ast
Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
@en
Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
@en-gb
Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
@nl
prefLabel
Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
@ast
Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
@en
Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
@en-gb
Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
@nl
P2093
P2860
P921
P3181
P1433
P1476
Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
@en
P2093
Henry H Jerng
Paul J Pfaffinger
P2860
P304
P3181
P356
10.1529/BIOPHYSJ.104.042358
P407
P577
2004-10-01T00:00:00Z