Impairment of cytoplasmic eIF6 activity restricts lymphomagenesis and tumor progression without affecting normal growth
about
Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturationRACK1 depletion in a mouse model causes lethality, pigmentation deficits and reduction in protein synthesis efficiencyeIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcriptionHuman macrophage ferroportin biology and the basis for the ferroportin disease.New frontiers in translational control of the cancer genomeAn integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer.Functional analysis of a novel glioma antigen, EFTUD1.EIF6 over-expression increases the motility and invasiveness of cancer cells by modulating the expression of a critical subset of membrane-bound proteinsThe translation factor eIF6 is a Notch-dependent regulator of cell migration and invasionProteomic and protein interaction network analysis of human T lymphocytes during cell-cycle entrySBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention.Tumor suppression by small molecule inhibitors of translation initiation.Expression and activity of eIF6 trigger malignant pleural mesothelioma growth in vivo.Translational control in cancer etiology.Targeting MYC in cancer therapy: RNA processing offers new opportunities.The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth.Role of microRNAs in translation regulation and cancer.Improving the outcomes: developing cancer therapeutics.Translation factors and ribosomal proteins control tumor onset and progression: how?Ribosomal proteins as novel players in tumorigenesis.Investigating Myc-dependent translational regulation in normal and cancer cells.The role of eukaryotic translation initiation factor 6 in tumorsDirect and high throughput (HT) interactions on the ribosomal surface by iRIA.mRNA fate: Life and death of the mRNA in the cytoplasm.Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6.How Ribosomes Translate Cancer.Loss-of-function uORF mutations in human malignancies.eIF2α Phosphorylation Mediates IL24-Induced Apoptosis through Inhibition of Translation.A Polysome-Based microRNA Screen Identifies miR-24-3p as a Novel Promigratory miRNA in Mesothelioma
P2860
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P2860
Impairment of cytoplasmic eIF6 activity restricts lymphomagenesis and tumor progression without affecting normal growth
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Impairment of cytoplasmic eIF6 ...... ithout affecting normal growth
@ast
Impairment of cytoplasmic eIF6 ...... ithout affecting normal growth
@en
Impairment of cytoplasmic eIF6 ...... ithout affecting normal growth
@en-gb
Impairment of cytoplasmic eIF6 ...... ithout affecting normal growth
@nl
type
label
Impairment of cytoplasmic eIF6 ...... ithout affecting normal growth
@ast
Impairment of cytoplasmic eIF6 ...... ithout affecting normal growth
@en
Impairment of cytoplasmic eIF6 ...... ithout affecting normal growth
@en-gb
Impairment of cytoplasmic eIF6 ...... ithout affecting normal growth
@nl
prefLabel
Impairment of cytoplasmic eIF6 ...... ithout affecting normal growth
@ast
Impairment of cytoplasmic eIF6 ...... ithout affecting normal growth
@en
Impairment of cytoplasmic eIF6 ...... ithout affecting normal growth
@en-gb
Impairment of cytoplasmic eIF6 ...... ithout affecting normal growth
@nl
P2093
P50
P3181
P1433
P1476
Impairment of cytoplasmic eIF6 ...... ithout affecting normal growth
@en
P2093
Annarita Miluzio
Anne Beugnet
Ario de Marco
Daniela Brina
Marilena Mancino
P304
P3181
P356
10.1016/J.CCR.2011.04.018
P407
P577
2011-06-01T00:00:00Z