Heat shock protein 90 as an endogenous protein enhancer of inducible nitric-oxide synthase
about
Nitric oxide acts as a positive regulator to induce metamorphosis of the ascidian Herdmania momusHeat shock regulates the respiration of cardiac H9c2 cells through upregulation of nitric oxide synthaseUpregulation and intrarenal redistribution of heat shock proteins 90alpha and 90beta by low-sodium diet in the rat.A critical role for CHIP in the aggresome pathwayHeat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/lpr mouse model of systemic lupus erythematosusGeldanamycin analog 17-DMAG limits apoptosis in human peripheral blood cells by inhibition of p53 activation and its interaction with heat-shock protein 90 kDa after exposure to ionizing radiationStructural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain.A synthetic analogue of 20-HETE, 5,14-HEDGE, reverses endotoxin-induced hypotension via increased 20-HETE levels associated with decreased iNOS protein expression and vasodilator prostanoid production in ratsA novel pathway for receptor-mediated post-translational activation of inducible nitric oxide synthase.Regulation of inducible nitric oxide synthase by aggresome formation.Hsp90β inhibition modulates nitric oxide production and nitric oxide-induced apoptosis in human chondrocytes17-AAG kills intracellular Leishmania amazonensis while reducing inflammatory responses in infected macrophages.Proposal for a role of the Hsp90/Hsp70-based chaperone machinery in making triage decisions when proteins undergo oxidative and toxic damage.The -144C/A polymorphism in the promoter of HSP90beta is associated with multiple organ dysfunction scoresHsp90 interacts with inducible NO synthase client protein in its heme-free state and then drives heme insertion by an ATP-dependent process.A model in which heat shock protein 90 targets protein-folding clefts: rationale for a new approach to neuroprotective treatment of protein folding diseasesObligatory role of heat shock protein 90 in iNOS induction.Heme-dependent activation of neuronal nitric oxide synthase by cytosol is due to an Hsp70-dependent, thioredoxin-mediated thiol-disulfide interchange in the heme/substrate binding cleftPiroxicam reverses endotoxin-induced hypotension in rats: contribution of vasoactive eicosanoids and nitric oxideModulation of heme/substrate binding cleft of neuronal nitric-oxide synthase (nNOS) regulates binding of Hsp90 and Hsp70 proteins and nNOS ubiquitinationHeat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis17-DMAG, an HSP90 Inhibitor, Ameliorates Multiple Organ Dysfunction Syndrome via Induction of HSP70 in Endotoxemic Rats.Soluble guanylyl cyclase requires heat shock protein 90 for heme insertion during maturation of the NO-active enzyme.Fungal heat-shock proteins in human disease.iNOS-dependent sweating and eNOS-dependent cutaneous vasodilation are evident in younger adults, but are diminished in older adults exercising in the heatStromal cell-derived factor 2 is critical for Hsp90-dependent eNOS activation.The novel HSP90 inhibitor, PU-H71, suppresses glial cell activation but weakly affects clinical signs of EAE.Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91(phox) to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shockCalcineurin regulates myocardial function during acute endotoxemiaProteomic analysis of the NOS2 interactome in human airway epithelial cellsSpecificity in S-nitrosylation: a short-range mechanism for NO signaling?Dynamic cycling with Hsp90 stabilizes neuronal nitric oxide synthase through calmodulin-dependent inhibition of ubiquitination.Just say NO: nitric oxide regulation of Hsp90.Epigallocatechin-3-gallate (EGCG) attenuates inflammation in MRL/lpr mouse mesangial cells.Stimulation, protection and regeneration of dopaminergic neurons by 9-methyl-β-carboline: a new anti-Parkinson drug?Transcriptome analysis during the process of in vitro differentiation of Leishmania donovani using genomic microarrays.Activation of the stress protein response inhibits the STAT1 signalling pathway and iNOS function in alveolar macrophages: role of Hsp90 and Hsp70.Regulation of iNOS-Derived ROS Generation by HSP90 and Cav-1 in Porcine Reproductive and Respiratory Syndrome Virus-Infected Swine Lung Injury.Heat shock-induced attenuation of hydroxyl radical generation and mitochondrial aconitase activity in cardiac H9c2 cells.alpha-lipoic acid inhibits endotoxin-stimulated expression of iNOS and nitric oxide independent of the heat shock response in RAW 264.7 cells.
P2860
28e1c890107a258720ae694b04f97b8a2800daef33a7c68c8eca8dbd27637e366b635d5fdeee9e24355c67f705f936472d3a0d7bfac5016482819d6c5fcf01a223d6131a8955a07abaee148c1b7f365e6ffce610ed3e7c1e02e9452625c2faeade79f8a9936c3fbe15c75ce1cd76463026aa7ea51f6ff938a04bcbac6654d83c740bcfed2be5a7f5f61242dbabaa0b12a6a48445b17e057345ba0e9291a655a5acebef75bd3d00a56f6fefdce8e8d55507ad742baf4209dc3badc119614f67ab19f548b41641917bb1b981f5d08d628c94dc01f13464956655b54a15b25913f898943fb670bac79511f2c7d9eb9e41e0d428549e2ae736acacc1155a8eed29a564736606ea42feb96ad36589bc3fddfcabd37f4a8d2b9e56
P248
Q27308766-3402AE17-3575-4B58-99A8-C085FD3D23E2Q28565622-7BDC5345-60E7-4F45-8E86-3C7F77D3DD3DQ28581309-3609A461-1C54-4097-ACEA-27926F79FD30Q30485241-43D1A39C-E68A-4CED-B301-0157C08C51B3Q33577386-F9687E13-BDC4-4BBB-A923-8142C75256DCQ33825349-A34A3C8F-ACD8-4485-85D3-CD2585AFA4E6Q33830350-EE78EBA2-8F7B-4F8C-9856-D9241BAC902CQ33900988-B77F3F30-A803-4375-8C08-4AB439092232Q33925096-9D159DEF-6371-4863-9762-28A37C18539CQ33935202-93B35376-C393-4058-9E7A-3318B9126FE8Q34049580-D1147FF3-4412-4E6E-BA1D-D6B0211EE7E9Q34478035-AE07498F-7D90-48A9-8980-8AD338A736DDQ34611621-2F96AFF0-410B-408B-97B0-20408BF1DF3EQ34629884-84124133-D3CA-4322-B44D-A4A5EBA1FC68Q35003199-491FC0D6-866F-4FF1-BC94-E059E2E7373BQ35053633-A115EBBD-E785-497B-A7EE-66658B82F818Q35086748-B5E0089A-67C7-4DA2-88C5-BDAE3998FF21Q35166930-95B3F7C2-1811-49A3-83F6-F64EE512D4B4Q35173157-BBBEFC84-0BC4-451A-BF56-3CE8DCB7A0BFQ35668831-0EDD3580-277D-4AC1-9E42-6A1904CB853FQ36013740-20658FBF-3998-4928-B411-78FCF0B1A0F3Q36029324-9EA78895-4856-4D46-A7BD-56E5D1240D3EQ36167665-CCBCC8F3-3924-4500-B8A5-E971A766F306Q36378357-AFB9ACE3-16EC-4E6D-ACD2-87C6DE85EC25Q36541465-DCFC4F8C-BF42-4513-B1FD-0097F3AED6DEQ36682953-F880891C-9570-45A8-B67C-7098A6F2651DQ37010253-5ACAAE9C-7303-4C11-AC3A-BEAE7C8B3C76Q37138417-BC62A52A-2758-436E-AD7D-7126E648B6E6Q37144330-E1E13E61-5E3D-4768-924C-68100C550798Q37161361-5238A28E-395A-4A38-AD10-C6BBE625CBB6Q37204142-04E98C91-5E02-4510-BDFB-166093DD54D6Q37355177-A2FDF8A7-6409-4A47-AA5B-C613144C2B32Q37381944-DEDE9331-6C83-46DC-A095-E2DD98C88610Q37727280-D4F8507D-EC56-4F53-BFCA-13DE07131DE6Q37886152-BE14D2B7-1395-4A2F-8D1B-4C98630E68F5Q39485122-E3502F72-8583-4719-B176-FA2C95FD6A95Q39715278-EB843157-0FE1-42D2-8CA2-99A56BB50E31Q40206149-C0F6B0BE-34CC-479F-9B68-0A1CE602DFC1Q40373539-6F41CB11-BAFD-488A-BFA9-A45041A6209AQ40510001-4B93F1EE-F8AA-4CDA-883B-BF06DD2B90D7
P2860
Heat shock protein 90 as an endogenous protein enhancer of inducible nitric-oxide synthase
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Heat shock protein 90 as an en ...... nducible nitric-oxide synthase
@ast
Heat shock protein 90 as an en ...... nducible nitric-oxide synthase
@en
Heat shock protein 90 as an en ...... nducible nitric-oxide synthase
@en-gb
Heat shock protein 90 as an en ...... nducible nitric-oxide synthase
@nl
type
label
Heat shock protein 90 as an en ...... nducible nitric-oxide synthase
@ast
Heat shock protein 90 as an en ...... nducible nitric-oxide synthase
@en
Heat shock protein 90 as an en ...... nducible nitric-oxide synthase
@en-gb
Heat shock protein 90 as an en ...... nducible nitric-oxide synthase
@nl
prefLabel
Heat shock protein 90 as an en ...... nducible nitric-oxide synthase
@ast
Heat shock protein 90 as an en ...... nducible nitric-oxide synthase
@en
Heat shock protein 90 as an en ...... nducible nitric-oxide synthase
@en-gb
Heat shock protein 90 as an en ...... nducible nitric-oxide synthase
@nl
P3181
P356
P1476
Heat shock protein 90 as an en ...... nducible nitric-oxide synthase
@en
P2093
Masako Yoshida
P304
P3181
P356
10.1074/JBC.M305214200
P407
P577
2003-09-19T00:00:00Z