Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damage
about
Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compoundsHepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells.URI promotes the migration and invasion of human cervical cancer cells potentially via upregulation of vimentin expression.Oncogene-induced NAD(+) depletion in tumorigenesis.URI expression in cervical cancer cells is associated with higher invasion capacity and resistance to cisplatin.NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the NucleusEliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice.Boosting NAD(+) for the prevention and treatment of liver cancer.Colorectal cancer cells display chaperone dependency for the unconventional prefoldin URI1.Tumour microenvironment factors shaping the cancer metabolism landscape.Physiological and pathophysiological roles of NAMPT and NAD metabolism.Protein acetylation in metabolism - metabolites and cofactors.Overexpression of Protein Phosphatase 1γ (PP1γ) Is Associated with Enhanced Cell Proliferation and Poor Prognosis in Hepatocellular Carcinoma.NAD+ metabolism: Bioenergetics, signaling and manipulation for therapy.NAD(+) : a key metabolic regulator with great therapeutic potential.URI prevents potassium dichromate-induced oxidative stress and cell death in gastric cancer cells.Hepatic NAD(+) deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing.Nicotinamide riboside or IL-17A signaling blockers to prevent liver disordersCould NAMPT inhibition become a potential treatment option in hepatocellular carcinoma?Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice.NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR.A human-specific switch of alternatively spliced AFMID isoforms contributes to TP53 mutations and tumor recurrence in hepatocellular carcinoma.The Pharmacology of CD38/NADase: An Emerging Target in Cancer and Diseases of Aging.Targeting NAD+ in Metabolic Disease: New Insights Into an Old Molecule.Nicotinamide riboside attenuates alcohol induced liver injuries via activation of SirT1/PGC-1α/mitochondrial biosynthesis pathway.
P2860
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P2860
Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damage
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2014 nî lūn-bûn
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2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
@zh-hant
2014年論文
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2014年論文
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2014年論文
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2014年论文
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Inhibition of de novo NAD(+) s ...... morigenesis through DNA damage
@ast
Inhibition of de novo NAD(+) s ...... morigenesis through DNA damage
@en
Inhibition of de novo NAD(+) s ...... morigenesis through DNA damage
@en-gb
Inhibition of de novo NAD(+) s ...... morigenesis through DNA damage
@nl
type
label
Inhibition of de novo NAD(+) s ...... morigenesis through DNA damage
@ast
Inhibition of de novo NAD(+) s ...... morigenesis through DNA damage
@en
Inhibition of de novo NAD(+) s ...... morigenesis through DNA damage
@en-gb
Inhibition of de novo NAD(+) s ...... morigenesis through DNA damage
@nl
prefLabel
Inhibition of de novo NAD(+) s ...... morigenesis through DNA damage
@ast
Inhibition of de novo NAD(+) s ...... morigenesis through DNA damage
@en
Inhibition of de novo NAD(+) s ...... morigenesis through DNA damage
@en-gb
Inhibition of de novo NAD(+) s ...... morigenesis through DNA damage
@nl
P2093
P50
P921
P3181
P1433
P1476
Inhibition of de novo NAD(+) s ...... morigenesis through DNA damage
@en
P2093
Ana L Gomes
Isabel Ruppen
Krishna S Tummala
Mahmut Yilmaz
Osvaldo Graña
Vinayata Sheshappanavar
P304
P3181
P356
10.1016/J.CCELL.2014.10.002
P407
P577
2014-11-20T00:00:00Z