The Barrett's antigen anterior gradient-2 silences the p53 transcriptional response to DNA damage
about
Anterior gradient-2 plays a critical role in breast cancer cell growth and survival by modulating cyclin D1, estrogen receptor-alpha and survivinAGR2 predicts tamoxifen resistance in postmenopausal breast cancer patientsThe protein disulfide isomerase AGR2 is essential for production of intestinal mucusDifferential expression of anterior gradient gene AGR2 in prostate cancerData-independent proteomic screen identifies novel tamoxifen agonist that mediates drug resistanceThe estrogen-responsive Agr2 gene regulates mammary epithelial proliferation and facilitates lobuloalveolar developmentThe metastasis-associated anterior gradient 2 protein is correlated with poor survival of breast cancer patientsIdentification, characterization and application of a G-quadruplex structured DNA aptamer against cancer biomarker protein anterior gradient homolog 2AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and DA novel p53 phosphorylation site within the MDM2 ubiquitination signal: I. phosphorylation at SER269 in vivo is linked to inactivation of p53 function.Quantitative Shotgun Proteomics Unveils Candidate Novel Esophageal Adenocarcinoma (EAC)-specific Proteins.Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia.Surprisal analysis characterizes the free energy time course of cancer cells undergoing epithelial-to-mesenchymal transitionKnockdown of anterior gradient 2 expression extenuates tumor-associated phenotypes of SNU-478 ampulla of Vater cancer cells.Development of a fluorescent monoclonal antibody-based assay to measure the allosteric effects of synthetic peptides on self-oligomerization of AGR2 protein.Anterior gradient 2 is expressed and secreted during the development of pancreatic cancer and promotes cancer cell survivalAGR3 in breast cancer: prognostic impact and suitable serum-based biomarker for early cancer detection.Role of pro-oncogenic protein disulfide isomerase (PDI) family member anterior gradient 2 (AGR2) in the control of endoplasmic reticulum homeostasis.Anterior gradient protein 2 expression in high grade head and neck squamous cell carcinoma correlated with cancer stem cell and epithelial mesenchymal transition.Post-translational modification of p53 in tumorigenesis.Evaluation of the adenocarcinoma-associated gene AGR2 and the intestinal stem cell marker LGR5 as biomarkers in colorectal cancer.Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cellsAGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia.AGR2 is associated with gastric cancer progression and poor survival.Molecular basis of Barrett's oesophagus and oesophageal adenocarcinomaiTRAQ-Based and Label-Free Proteomics Approaches for Studies of Human Adenovirus InfectionsThe estrogen-regulated anterior gradient 2 (AGR2) protein in breast cancer: a potential drug target and biomarkerAnterior gradient-2 is overexpressed by fibrolamellar carcinomas.AGR2 promotes the proliferation, migration and regulates epithelial-mesenchymal transition in salivary adenoid cystic carcinoma.Identification of novel HLA-A*0201-restricted epitopes from anterior gradient-2 as a tumor-associated antigen against colorectal cancer.Dioxin toxicity, aryl hydrocarbon receptor signaling, and apoptosis-persistent pollutants affect programmed cell death.Emerging roles for the pro-oncogenic anterior gradient-2 in cancer development.Differential gene expression in normal esophagus and Barrett's esophagus.Transcriptome profiling the gills of amoebic gill disease (AGD)-affected Atlantic salmon (Salmo salar L.): a role for tumor suppressor p53 in AGD pathogenesis?Engineering a synthetic cell panel to identify signalling components reprogrammed by the cell growth regulator anterior gradient-2.AGR2 expression is regulated by HIF-1 and contributes to growth and angiogenesis of glioblastoma.Proteomic study explores AGR2 as pro-metastatic protein in HCC.Quantitative proteome analysis of ovarian cancer tissues using a iTRAQ approach.2,3,7,8-tetrachlorodibenzo-p-dioxin counteracts the p53 response to a genotoxicant by upregulating expression of the metastasis marker agr2 in the hepatocarcinoma cell line HepG2.AGR2 oncoprotein inhibits p38 MAPK and p53 activation through a DUSP10-mediated regulatory pathway.
P2860
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P2860
The Barrett's antigen anterior gradient-2 silences the p53 transcriptional response to DNA damage
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The Barrett's antigen anterior ...... ptional response to DNA damage
@ast
The Barrett's antigen anterior ...... ptional response to DNA damage
@en
The Barrett's antigen anterior ...... ptional response to DNA damage
@en-gb
The Barrett's antigen anterior ...... ptional response to DNA damage
@nl
type
label
The Barrett's antigen anterior ...... ptional response to DNA damage
@ast
The Barrett's antigen anterior ...... ptional response to DNA damage
@en
The Barrett's antigen anterior ...... ptional response to DNA damage
@en-gb
The Barrett's antigen anterior ...... ptional response to DNA damage
@nl
prefLabel
The Barrett's antigen anterior ...... ptional response to DNA damage
@ast
The Barrett's antigen anterior ...... ptional response to DNA damage
@en
The Barrett's antigen anterior ...... ptional response to DNA damage
@en-gb
The Barrett's antigen anterior ...... ptional response to DNA damage
@nl
P2093
P1476
The Barrett's antigen anterior ...... ptional response to DNA damage
@en
P2093
Ashley L Craig
Elizabeth Pohler
James Cotton
Laura Lawrie
Neil Kernohan
Ted R Hupp
P304
P356
10.1074/MCP.M300089-MCP200
P407
P577
2004-02-15T00:00:00Z