Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II
about
Phosphorylation-induced conformational changes in Rap1b: allosteric effects on switch domains and effector loopRas Homolog Enriched in Brain (Rheb) Enhances Apoptotic SignalingThe Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic TailStructural Basis for Small G Protein Effector Interaction of Ras-related Protein 1 (Rap1) and Adaptor Protein Krev Interaction Trapped 1 (KRIT1)Structural Basis for the Interaction of the Adaptor Protein Grb14 with Activated RasThe structure of Rap1 in complex with RIAM reveals specificity determinants and recruitment mechanismSurface-Attached Polyhistidine-Tag Proteins Characterized by FTIR Difference SpectroscopyRas history: The saga continues.A RASSF1A polymorphism restricts p53/p73 activation and associates with poor survival and accelerated age of onset of soft tissue sarcoma.Growth and tumor suppressor NORE1A is a regulatory node between Ras signaling and microtubule nucleation.The growth and tumor suppressors NORE1A and RASSF1A are targets for calpain-mediated proteolysis.MST1/MST2 Protein Kinases: Regulation and Physiologic Roles.Transplanting supersites of HIV-1 vulnerability.Cell cycle restriction is more important than apoptosis induction for RASSF1A protein tumor suppression.RASSF1A: Not a prototypical Ras effector.The RAS-Effector Interface: Isoform-Specific Differences in the Effector Binding RegionsScreening for protein-protein interactions using Förster resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM).Ras and rheb signaling in survival and cell deathRassf family of tumor suppressor polypeptides.Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression.The N-terminal RASSF family: a new group of Ras-association-domain-containing proteins, with emerging links to cancer formation.Structural dissection of Hippo signaling.Structures of Ras superfamily effector complexes: What have we learnt in two decades?Ras signaling through RASSF proteins.Drugging Ras GTPase: a comprehensive mechanistic and signaling structural view.The differential effects of wild-type and mutated K-Ras on MST2 signaling are determined by K-Ras activation kinetics.The role of the NORE1A tumor suppressor in Oncogene-Induced Senescence.Relation between the conformational heterogeneity and reaction cycle of Ras: molecular simulation of Ras.The Function of Embryonic Stem Cell-expressed RAS (E-RAS), a Unique RAS Family Member, Correlates with Its Additional Motifs and Its Structural Properties.SARAH Domain-Mediated MST2-RASSF Dimeric Interactions.Improved binding of raf to Ras.GDP is correlated with biological activity.Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders.Rassf Proteins as Modulators of Mst1 Kinase Activity.N-Ras forms dimers at POPC membranes.Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.Comparative analysis of interactions of RASSF1-10.Photocontrol of the GTPase activity of the small G protein K-Ras by using an azobenzene derivative.Functional analysis of a duplication (p.E63_D69dup) in the switch II region of HRAS: new aspects of the molecular pathogenesis underlying Costello syndrome.Structural Dynamics in Ras and Related Proteins upon Nucleotide Switching.Comparative Modeling, Molecular Docking, and Revealing of Potential Binding Pockets of RASSF2; a Candidate Cancer Gene.
P2860
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P2860
Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Novel type of Ras effector int ...... essor NORE1A and Ras switch II
@ast
Novel type of Ras effector int ...... essor NORE1A and Ras switch II
@en
Novel type of Ras effector int ...... essor NORE1A and Ras switch II
@en-gb
Novel type of Ras effector int ...... essor NORE1A and Ras switch II
@nl
type
label
Novel type of Ras effector int ...... essor NORE1A and Ras switch II
@ast
Novel type of Ras effector int ...... essor NORE1A and Ras switch II
@en
Novel type of Ras effector int ...... essor NORE1A and Ras switch II
@en-gb
Novel type of Ras effector int ...... essor NORE1A and Ras switch II
@nl
prefLabel
Novel type of Ras effector int ...... essor NORE1A and Ras switch II
@ast
Novel type of Ras effector int ...... essor NORE1A and Ras switch II
@en
Novel type of Ras effector int ...... essor NORE1A and Ras switch II
@en-gb
Novel type of Ras effector int ...... essor NORE1A and Ras switch II
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Novel type of Ras effector int ...... essor NORE1A and Ras switch II
@en
P2093
Andrei Khokhlatchev
Anna Moshnikova
Christian Herrmann
Christine Bee
Daniel Schwarz
Ozkan Yildiz
P2860
P304
P3181
P356
10.1038/EMBOJ.2008.125
P407
P577
2008-07-03T00:00:00Z