Mapping of interaction domains between human repair proteins ERCC1 and XPF - Wikidata - wikimedia - TriplyDB

Mapping of interaction domains between human repair proteins ERCC1 and XPF

Mapping of interaction domains between human repair proteins ERCC1 and XPF

http://www.wikidata.org/entity/Q24309451

about

Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1 First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure Nucleases in homologous recombination as targets for cancer therapy DNA repair endonuclease ERCC1-XPF as a novel therapeutic target to overcome chemoresistance in cancer therapy Architecture and DNA Recognition Elements of the Fanconi Anemia FANCM-FAAP24 Complex Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease Activity of individual ERCC1 and XPF subunits in DNA nucleotide excision repair The active site of the DNA repair endonuclease XPF-ERCC1 forms a highly conserved nuclease motif.Physiological consequences of defects in ERCC1-XPF DNA repair endonuclease Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF The Cerebro-oculo-facio-skeletal Syndrome Point Mutation F231L in the ERCC1 DNA Repair Protein Causes Dissociation of the ERCC1-XPF Complex DNA repair gets physical: mapping an XPA-binding site on ERCC1 The role of Bcl-x(L) protein in nucleotide excision repair-facilitated cell protection against cisplatin-induced apoptosis.Mislocalization of XPF-ERCC1 nuclease contributes to reduced DNA repair in XP-F patients Molecular interaction map of the mammalian cell cycle control and DNA repair systems.Differential processing of UV mimetic and interstrand crosslink damage by XPF cell extracts.The Fanconi anemia protein, FANCG, binds to the ERCC1-XPF endonuclease via its tetratricopeptide repeats and the central domain of ERCC1.Role of interaction of XPF with RPA in nucleotide excision repair.Identification and characterization of the human mus81-eme1 endonuclease.Multiple DNA binding domains mediate the function of the ERCC1-XPF protein in nucleotide excision repair.Mutational analysis of the Drosophila DNA repair and recombination gene mei-9 Expression of domains for protein-protein interaction of nucleotide excision repair proteins modifies cancer cell sensitivity to platinum derivatives and genomic stability.The ERCC1 and ERCC4 (XPF) genes and gene products Nuclear alpha spectrin: Critical roles in DNA interstrand cross-link repair and genomic stability.ERCC1: impact in multimodality treatment of upper gastrointestinal cancer.Regulation of endonuclease activity in human nucleotide excision repair.AtRAD1, a plant homologue of human and yeast nucleotide excision repair endonucleases, is involved in dark repair of UV damages and recombination.DNA Repair Endonucleases: Physiological Roles and Potential as Drug Targets.Disruption of DNA repair in cancer cells by ubiquitination of a destabilising dimerization domain of nucleotide excision repair protein ERCC1.ERCC4 variants identified in a cohort of patients with segmental progeroid syndromes.Splice variants of the endonucleases XPF and XPG contain residual DNA repair capabilities and could be a valuable tool for personalized medicine.Single-stranded DNA Binding by the Helix-Hairpin-Helix Domain of XPF Protein Contributes to the Substrate Specificity of the ERCC1-XPF Protein Complex.Spectrin and its interacting partners in nuclear structure and function.Evaluation of rare variants in the new fanconi anemia gene ERCC4 (FANCQ) as familial breast/ovarian cancer susceptibility alleles.Biophysical characterization of the interaction domains and mapping of the contact residues in the XPF-ERCC1 complex.

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P2860

Mapping of interaction domains between human repair proteins ERCC1 and XPF

http://www.wikidata.org/entity/Q24309451

description

1998 nî lūn-bûn

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1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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name

Mapping of interaction domains between human repair proteins ERCC1 and XPF

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Mapping of interaction domains between human repair proteins ERCC1 and XPF

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Mapping of interaction domains between human repair proteins ERCC1 and XPF

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Mapping of interaction domains between human repair proteins ERCC1 and XPF

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label

Mapping of interaction domains between human repair proteins ERCC1 and XPF

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Mapping of interaction domains between human repair proteins ERCC1 and XPF

@en

Mapping of interaction domains between human repair proteins ERCC1 and XPF

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Mapping of interaction domains between human repair proteins ERCC1 and XPF

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prefLabel

Mapping of interaction domains between human repair proteins ERCC1 and XPF

@ast

Mapping of interaction domains between human repair proteins ERCC1 and XPF

@en

Mapping of interaction domains between human repair proteins ERCC1 and XPF

@en-gb

Mapping of interaction domains between human repair proteins ERCC1 and XPF

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Nucleic Acids Research

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Mapping of interaction domains between human repair proteins ERCC1 and XPF

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P2093

A M Sijbers

http://www.w3.org/2001/XMLSchema#string

H Odijk

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J H Hoeijmakers

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N G Jaspers

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P2860

Evolution and mutagenesis of the mammalian excision repair gene ERCC-1

Purification and characterization of the XPF-ERCC1 complex of human DNA repair excision nuclease

Formation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteins

Reconstitution of human excision nuclease with recombinant XPF-ERCC1 complex

XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair

Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease

Mutational analysis of the human nucleotide excision repair gene ERCC1

Human DNA repair excision nuclease. Analysis of the roles of the subunits involved in dual incisions by using anti-XPG and anti-ERCC1 antibodies

The characterization of a mammalian DNA structure-specific endonuclease

Specific association between the human DNA repair proteins XPA and ERCC1

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4146-4152

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scholarly article

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10.1093/NAR/26.18.4146

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18

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26

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9722633

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protein C-terminus binding

ERCC excision repair 1, endonuclease non-catalytic subunit

ERCC excision repair 4, endonuclease catalytic subunit

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147836

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