The vaccinia virus protein F1L interacts with Bim and inhibits activation of the pro-apoptotic protein Bax
about
Orthopoxvirus genes that mediate disease virulence and host tropismVaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligandsActivation of the PI3K/Akt Pathway Early during Vaccinia and Cowpox Virus Infections Is Required for both Host Survival and Viral ReplicationStructure of M11L: A myxoma virus structural homolog of the apoptosis inhibitor, Bcl-2Structural Insight into BH3 Domain Binding of Vaccinia Virus Antiapoptotic F1LA survey of host range genes in poxvirus genomesThe N Terminus of the Vaccinia Virus Protein F1L Is an Intrinsically Unstructured Region That Is Not Involved in Apoptosis Regulation.A novel Bcl-2-like inhibitor of apoptosis is encoded by the parapoxvirus ORF virusBim, Bak, and Bax regulate osteoblast survival.Vaccinia virus protein F1L is a caspase-9 inhibitorInduction of Noxa-mediated apoptosis by modified vaccinia virus Ankara depends on viral recognition by cytosolic helicases, leading to IRF-3/IFN-β-dependent induction of pro-apoptotic Noxa.Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance.Enhanced tumor therapy using vaccinia virus strain GLV-1h68 in combination with a β-galactosidase-activatable prodrug seco-analog of duocarmycin SA.Multiple functions of BCL-2 family proteins.Deletion of the viral anti-apoptotic gene F1L in the HIV/AIDS vaccine candidate MVA-C enhances immune responses against HIV-1 antigensDeerpox virus encodes an inhibitor of apoptosis that regulates Bak and Bax.Structural determinants of caspase-9 inhibition by the vaccinia virus protein, F1LVariola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim.Genomic Analysis, Phenotype, and Virulence of the Historical Brazilian Smallpox Vaccine Strain IOC: Implications for the Origins and Evolutionary Relationships of Vaccinia VirusSheeppox virus SPPV14 encodes a Bcl-2-like cell death inhibitor that counters a distinct set of mammalian proapoptotic proteins.The Epstein-Barr virus Bcl-2 homolog, BHRF1, blocks apoptosis by binding to a limited amount of BimThe fowlpox virus BCL-2 homologue, FPV039, interacts with activated Bax and a discrete subset of BH3-only proteins to inhibit apoptosis.Involvement of the cellular phosphatase DUSP1 in vaccinia virus infection.Oncolytic vaccinia virus for the treatment of cancer.Viruses as modulators of mitochondrial functions.Cellular unfolded protein response against viruses used in gene therapyThe matrix (M) protein of Newcastle disease virus binds to human bax through its BH3 domain.The vaccinia virus-encoded Bcl-2 homologues do not act as direct Bax inhibitors.Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1.Vaccinia virus encodes a novel inhibitor of apoptosis that associates with the apoptosome.The Bcl-2 Family in Host-Virus Interactions.Vaccinia-induced epidermal growth factor receptor-MEK signalling and the anti-apoptotic protein F1L synergize to suppress cell death during infection.Fowlpox virus encodes a Bcl-2 homologue that protects cells from apoptotic death through interaction with the proapoptotic protein Bak.E3L and F1L Gene Functions Modulate the Protective Capacity of Modified Vaccinia Virus Ankara Immunization in Murine Model of Human Smallpox.
P2860
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P2860
The vaccinia virus protein F1L interacts with Bim and inhibits activation of the pro-apoptotic protein Bax
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The vaccinia virus protein F1L ...... the pro-apoptotic protein Bax
@ast
The vaccinia virus protein F1L ...... the pro-apoptotic protein Bax
@en
The vaccinia virus protein F1L ...... the pro-apoptotic protein Bax
@en-gb
The vaccinia virus protein F1L ...... the pro-apoptotic protein Bax
@nl
type
label
The vaccinia virus protein F1L ...... the pro-apoptotic protein Bax
@ast
The vaccinia virus protein F1L ...... the pro-apoptotic protein Bax
@en
The vaccinia virus protein F1L ...... the pro-apoptotic protein Bax
@en-gb
The vaccinia virus protein F1L ...... the pro-apoptotic protein Bax
@nl
prefLabel
The vaccinia virus protein F1L ...... the pro-apoptotic protein Bax
@ast
The vaccinia virus protein F1L ...... the pro-apoptotic protein Bax
@en
The vaccinia virus protein F1L ...... the pro-apoptotic protein Bax
@en-gb
The vaccinia virus protein F1L ...... the pro-apoptotic protein Bax
@nl
P2093
P2860
P356
P1476
The vaccinia virus protein F1L ...... the pro-apoptotic protein Bax
@en
P2093
Douglas Quilty
John M Taylor
Logan Banadyga
Michele Barry
P2860
P304
P356
10.1074/JBC.M607465200
P407
P577
2006-12-22T00:00:00Z