A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway
about
Loss of CHSY1, a secreted FRINGE enzyme, causes syndromic brachydactyly in humans via increased NOTCH signalingMutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotypeProtein O-fucosyltransferase 1 is an essential component of Notch signaling pathwaysFringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligandsNotch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse developmentFringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1O-fucosylation of DLL3 is required for its function during somitogenesisDefects in limb, craniofacial, and thymic development in Jagged2 mutant miceA POGLUT1 mutation causes a muscular dystrophy with reduced Notch signaling and satellite cell loss.Understanding normal and abnormal development of the Wolffian/epididymal duct by using transgenic mice.Differential axial requirements for lunatic fringe and Hes7 transcription during mouse somitogenesis.Expression study of cadherin7 and cadherin20 in the embryonic and adult rat central nervous system.Glycogenome expression dynamics during mouse C2C12 myoblast differentiation suggests a sequential reorganization of membrane glycoconjugates.Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.The Notch-2 gene is regulated by Wnt signaling in cultured colorectal cancer cellsFringe modulation of Jagged1-induced Notch signaling requires the action of beta 4galactosyltransferase-1Role of glycosylation of Notch in developmentFringe benefits: functional and structural impacts of O-glycosylation on the extracellular domain of Notch receptorsNovel genes upregulated when NOTCH signalling is disrupted during hypothalamic development.Fringe controls naïve CD4(+)T cells differentiation through modulating notch signaling in asthmatic rat models.Molecular and comparative genetics of mental retardation.A deficiency of lunatic fringe is associated with cystic dilation of the rete testis.Molecular genetic analysis of the glycosyltransferase Fringe in Drosophila.O-glucose trisaccharide is present at high but variable stoichiometry at multiple sites on mouse Notch1.Neurotrophins acting via TRKB receptors activate the JAGGED1-NOTCH2 cell-cell communication pathway to facilitate early ovarian development.Galactose differentially modulates lunatic and manic fringe effects on Delta1-induced NOTCH signaling.Altered Notch ligand expression in human liver disease: further evidence for a role of the Notch signaling pathway in hepatic neovascularization and biliary ductular defects.A 380-kb Duplication in 7p22.3 Encompassing the LFNG Gene in a Boy with Asperger Syndrome.Lunatic, Manic, and Radical Fringe Each Promote T and B Cell DevelopmentLunatic fringe causes expansion and increased neurogenesis of trunk neural tube and neural crest populationsLunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.Suppression of Notch signaling in the neonatal mouse ovary decreases primordial follicle formationLunatic fringe promotes the lateral inhibition of neurogenesisThe molecular logic of Notch signaling--a structural and biochemical perspective.Mammalian glycosylation in immunity.Nas transgenic mouse line allows visualization of Notch pathway activity in vivo.Activation of Notch signaling in human colon adenocarcinoma.NOTCH signaling in Sertoli cells regulates gonocyte fateManic fringe is not required for embryonic development, and fringe family members do not exhibit redundant functions in the axial skeleton, limb, or hindbrain.Transcriptional Regulation of Notch1 Expression by Nkx6.1 in Neural Stem/Progenitor Cells during Ventral Spinal Cord Development
P2860
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P2860
A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
A family of mammalian Fringe g ...... mination and the Notch pathway
@ast
A family of mammalian Fringe g ...... mination and the Notch pathway
@en
A family of mammalian Fringe g ...... mination and the Notch pathway
@en-gb
A family of mammalian Fringe g ...... mination and the Notch pathway
@nl
type
label
A family of mammalian Fringe g ...... mination and the Notch pathway
@ast
A family of mammalian Fringe g ...... mination and the Notch pathway
@en
A family of mammalian Fringe g ...... mination and the Notch pathway
@en-gb
A family of mammalian Fringe g ...... mination and the Notch pathway
@nl
prefLabel
A family of mammalian Fringe g ...... mination and the Notch pathway
@ast
A family of mammalian Fringe g ...... mination and the Notch pathway
@en
A family of mammalian Fringe g ...... mination and the Notch pathway
@en-gb
A family of mammalian Fringe g ...... mination and the Notch pathway
@nl
P2093
P3181
P1433
P1476
A family of mammalian Fringe g ...... mination and the Notch pathway
@en
P2093
B Prabhakaran
C Rauskolb
S H Johnston
P304
P3181
P407
P50
P577
1997-06-01T00:00:00Z