CEP290 interacts with the centriolar satellite component PCM-1 and is required for Rab8 localization to the primary cilium
about
Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington diseasePrimary ciliogenesis requires the distal appendage component Cep123.FAM161A, associated with retinitis pigmentosa, is a component of the cilia-basal body complex and interacts with proteins involved in ciliopathiesCep126 is required for pericentriolar satellite localisation to the centrosome and for primary cilium formationCentriolar association of ALMS1 and likely centrosomal functions of the ALMS motif-containing proteins C10orf90 and KIAA1731Proteomic analysis of mammalian sperm cells identifies new components of the centrosomeBardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signalingCEP90 is required for the assembly and centrosomal accumulation of centriolar satellites, which is essential for primary cilia formationOfd1, a human disease gene, regulates the length and distal structure of centriolesUNC119 is required for G protein trafficking in sensory neuronsCombining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesisThe novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zoneBBS mutations modify phenotypic expression of CEP290-related ciliopathiesThe CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assemblyOFD1 is mutated in X-linked Joubert syndrome and interacts with LCA5-encoded lebercilinA SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivoCasein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesisDisruption of CEP290 microtubule/membrane-binding domains causes retinal degenerationThe role of primary cilia in neuronal functionThe primary cilium as a cellular signaling center: lessons from diseaseMutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathiesHuman basal body basicsMolecular complexes that direct rhodopsin transport to primary ciliaRPGRIP1 and cone-rod dystrophy in dogsCEP290 alleles in mice disrupt tissue-specific cilia biogenesis and recapitulate features of syndromic ciliopathiesOFD1 and flotillins are integral components of a ciliary signaling protein complex organized by polycystins in renal epithelia and odontoblastsInvestigating embryonic expression patterns and evolution of AHI1 and CEP290 genes, implicated in Joubert syndromeAcute versus chronic loss of mammalian Azi1/Cep131 results in distinct ciliary phenotypesThe nonmotile ciliopathies.Trafficking to the ciliary membrane: how to get across the periciliary diffusion barrier?The Arf GAP ASAP1 provides a platform to regulate Arf4- and Rab11-Rab8-mediated ciliary receptor targeting.ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targetingCep164 mediates vesicular docking to the mother centriole during early steps of ciliogenesisTrafficking in and to the primary cilium.CP110 and its network of partners coordinately regulate cilia assembly.C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.Pathogenic NPHP5 mutations impair protein interaction with Cep290, a prerequisite for ciliogenesisCentriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplicationNephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo deliveryPar6 alpha interacts with the dynactin subunit p150 Glued and is a critical regulator of centrosomal protein recruitment
P2860
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P2860
CEP290 interacts with the centriolar satellite component PCM-1 and is required for Rab8 localization to the primary cilium
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
CEP290 interacts with the cent ...... lization to the primary cilium
@ast
CEP290 interacts with the cent ...... lization to the primary cilium
@en
CEP290 interacts with the cent ...... lization to the primary cilium
@en-gb
CEP290 interacts with the cent ...... lization to the primary cilium
@nl
type
label
CEP290 interacts with the cent ...... lization to the primary cilium
@ast
CEP290 interacts with the cent ...... lization to the primary cilium
@en
CEP290 interacts with the cent ...... lization to the primary cilium
@en-gb
CEP290 interacts with the cent ...... lization to the primary cilium
@nl
prefLabel
CEP290 interacts with the cent ...... lization to the primary cilium
@ast
CEP290 interacts with the cent ...... lization to the primary cilium
@en
CEP290 interacts with the cent ...... lization to the primary cilium
@en-gb
CEP290 interacts with the cent ...... lization to the primary cilium
@nl
P2860
P3181
P356
P1476
CEP290 interacts with the cent ...... lization to the primary cilium
@en
P2093
Suguna Rani Krishnaswami
P2860
P304
P3181
P356
10.1093/HMG/DDN277
P407
P577
2008-09-04T00:00:00Z