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Breaking Free of Control: How Conventional T Cells Overcome Regulatory T Cell Suppression.Indoctrinating T cells to attack pathogens through homeschoolingT Cell Costimulation by CD6 Is Dependent on Bivalent Binding of a GADS/SLP-76 Complex.HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory ReceptorsTHEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1.The human cytomegalovirus glycoprotein pUL11 acts via CD45 to induce T cell IL-10 secretion.Interleukin-4 receptor-targeted liposomal doxorubicin as a model for enhancing cellular uptake and antitumor efficacy in murine colorectal cancer.Constitutive Lck Activity Drives Sensitivity Differences between CD8+ Memory T Cell Subsets.Architecture of a minimal signaling pathway explains the T-cell response to a 1 million-fold variation in antigen affinity and dose.THEMIS: Two Models, Different Thresholds.Targeted loss of SHP1 in murine thymocytes dampens TCR signaling late in selectionThemis1 enhances T cell receptor signaling during thymocyte development by promoting Vav1 activity and Grb2 stability.TCR signalling network organization at the immunological synapses of murine regulatory T cells.Grb2 Is Important for T Cell Development, Th Cell Differentiation, and Induction of Experimental Autoimmune Encephalomyelitis.LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formationFine-Tuning of Optimal TCR Signaling in Tumor-Redirected CD8 T Cells by Distinct TCR Affinity-Mediated Mechanisms.Proteomic Analysis of Regulatory T Cells Reveals the Importance of Themis1 in the Control of Their Suppressive Function.Purification of LAT-Containing Membranes from Resting and Activated T Lymphocytes.Themis2 lowers the threshold for B cell activation during positive selection.Recruitment of calcineurin to the TCR positively regulates T cell activation.SHP1-ing thymic selection.A Jurkat 76 based triple parameter reporter system to evaluate TCR functions and adoptive T cell strategies.
P2860
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P2860
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
A THEMIS:SHP1 complex promotes T-cell survival
@ast
A THEMIS:SHP1 complex promotes T-cell survival
@en
A THEMIS:SHP1 complex promotes T-cell survival
@en-gb
A THEMIS:SHP1 complex promotes T-cell survival
@nl
type
label
A THEMIS:SHP1 complex promotes T-cell survival
@ast
A THEMIS:SHP1 complex promotes T-cell survival
@en
A THEMIS:SHP1 complex promotes T-cell survival
@en-gb
A THEMIS:SHP1 complex promotes T-cell survival
@nl
prefLabel
A THEMIS:SHP1 complex promotes T-cell survival
@ast
A THEMIS:SHP1 complex promotes T-cell survival
@en
A THEMIS:SHP1 complex promotes T-cell survival
@en-gb
A THEMIS:SHP1 complex promotes T-cell survival
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
A THEMIS:SHP1 complex promotes T-cell survival
@en
P2093
Andre Cohnen
Annika M Bruger
Claude Grégoire
Kelly C Molder
Konstantina Nika
Kristin Katsch
Philip C Simister
Shaun-Paul Cordoba
Stephan M Feller
P2860
P304
P3181
P356
10.15252/EMBJ.201387725
P407
P577
2015-02-03T00:00:00Z