USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A
about
A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complexThe Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylationUSP22 is a positive regulator of NFATc2 on promoting IL2 expressionRegulation and cellular roles of ubiquitin-specific deubiquitinating enzymesDUBbing Cancer: Deubiquitylating Enzymes Involved in Epigenetics, DNA Damage and the Cell Cycle As Therapeutic TargetsUbiquitin-specific peptidase 22 functions and its involvement in diseaseThe Importance of Ubiquitination and Deubiquitination in Cellular ReprogrammingComposition of the SAGA complex in plants and its role in controlling gene expression in response to abiotic stressesDeubiquitinating enzymes as oncotargetsUncovering the role of Sgf73 in maintaining SAGA deubiquitinating module structure and activity.USP22 knockdown enhanced chemosensitivity of hepatocellular carcinoma cells to 5-Fu by up-regulation of Smad4 and suppression of Akt.USP22 maintains gastric cancer stem cell stemness and promotes gastric cancer progression by stabilizing BMI1 proteinPulling complexes out of complex diseases: Spinocerebellar Ataxia 7.Aberrant expression of USP22 is associated with liver metastasis and poor prognosis of colorectal cancer.Elevated expression of USP22 in correlation with poor prognosis in patients with invasive breast cancer.The tightly controlled deubiquitination activity of the human SAGA complex differentially modifies distinct gene regulatory elementsKnock-down of ubiquitin-specific protease 22 by micro-RNA interference inhibits colorectal cancer growth.USP22 is useful as a novel molecular marker for predicting disease progression and patient prognosis of oral squamous cell carcinomaThe role of deubiquitinating enzymes in chromatin regulation.Regulation of histone H2A and H2B deubiquitination and Xenopus development by USP12 and USP46.USP22 promotes NSCLC tumorigenesis via MDMX up-regulation and subsequent p53 inhibition.Invadolysin acts genetically via the SAGA complex to modulate chromosome structure.The Roles of the Paf1 Complex and Associated Histone Modifications in Regulating Gene ExpressionHigh USP22 expression indicates poor prognosis in hepatocellular carcinoma.Aggregation of Polyglutamine-expanded Ataxin 7 Protein Specifically Sequesters Ubiquitin-specific Protease 22 and Deteriorates Its Deubiquitinating Function in the Spt-Ada-Gcn5-Acetyltransferase (SAGA) Complex.Usp22 deficiency impairs intestinal epithelial lineage specification in vivoOverexpression of ubiquitin-specific protease 22 predicts poor survival in patients with early-stage non-small cell lung cancerRNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated CancermiR-34b inhibits nasopharyngeal carcinoma cell proliferation by targeting ubiquitin-specific peptidase 22RNA interference-mediated USP22 gene silencing promotes human brain glioma apoptosis and induces cell cycle arrest.Targeting ubiquitin-specific protease 22 suppresses growth and metastasis of anaplastic thyroid carcinoma.The relationship between the expression of USP22, BMI1, and EZH2 in hepatocellular carcinoma and their impacts on prognosis.The WD40-repeat protein-containing deubiquitinase complex: catalysis, regulation, and potential for therapeutic intervention.Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration.Metabolic enzymes: key modulators of functionality in cancer stem-like cells.A portrayal of E3 ubiquitin ligases and deubiquitylases in cancer.Regulation of proteolysis by human deubiquitinating enzymes.DUBs, the regulation of cell identity and disease.Regulation of pluripotency and differentiation by deubiquitinating enzymes.ShRNA-mediated silencing of the ubiquitin-specific protease 22 gene restrained cell progression and affected the Akt pathway in nasopharyngeal carcinoma
P2860
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P2860
USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
USP22, an hSAGA subunit and po ...... ubiquitylation of histone H2A
@ast
USP22, an hSAGA subunit and po ...... ubiquitylation of histone H2A
@en
USP22, an hSAGA subunit and po ...... ubiquitylation of histone H2A
@en-gb
USP22, an hSAGA subunit and po ...... ubiquitylation of histone H2A
@nl
type
label
USP22, an hSAGA subunit and po ...... ubiquitylation of histone H2A
@ast
USP22, an hSAGA subunit and po ...... ubiquitylation of histone H2A
@en
USP22, an hSAGA subunit and po ...... ubiquitylation of histone H2A
@en-gb
USP22, an hSAGA subunit and po ...... ubiquitylation of histone H2A
@nl
prefLabel
USP22, an hSAGA subunit and po ...... ubiquitylation of histone H2A
@ast
USP22, an hSAGA subunit and po ...... ubiquitylation of histone H2A
@en
USP22, an hSAGA subunit and po ...... ubiquitylation of histone H2A
@en-gb
USP22, an hSAGA subunit and po ...... ubiquitylation of histone H2A
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
USP22, an hSAGA subunit and po ...... ubiquitylation of histone H2A
@en
P2093
Alan W Thorne
Harla K Pfeiffer
Steven B McMahon
Xiao-yong Zhang
P2860
P304
P3181
P356
10.4161/CC.7.11.5962
P407
P577
2008-06-01T00:00:00Z