Kinetic analysis of substrate utilization by native and TNAP-, NPP1-, or PHOSPHO1-deficient matrix vesicles
about
Phosphate/pyrophosphate and MV-related proteins in mineralisation: discoveries from mouse modelsExtracellular matrix mineralization in periodontal tissues: Noncollagenous matrix proteins, enzymes, and relationship to hypophosphatasia and X-linked hypophosphatemiaThe role of phosphatases in the initiation of skeletal mineralizationPHOSPHO1 is essential for mechanically competent mineralization and the avoidance of spontaneous fracturesLoss of skeletal mineralization by the simultaneous ablation of PHOSPHO1 and alkaline phosphatase function: a unified model of the mechanisms of initiation of skeletal calcificationPhosphate induces formation of matrix vesicles during odontoblast-initiated mineralization in vitroAssay format as a critical success factor for identification of novel inhibitor chemotypes of tissue-nonspecific alkaline phosphatase from high-throughput screeningInhibition of PHOSPHO1 activity results in impaired skeletal mineralization during limb development of the chickProteoliposomes harboring alkaline phosphatase and nucleotide pyrophosphatase as matrix vesicle biomimetics.Cellular function and molecular structure of ecto-nucleotidases.Tissue-nonspecific alkaline phosphatase deficiency causes abnormal craniofacial bone development in the Alpl(-/-) mouse model of infantile hypophosphatasiaDual role of the Trps1 transcription factor in dentin mineralization.Deletion of ENTPD3 does not impair nucleotide hydrolysis in primary somatosensory neurons or spinal cord.Extracellular pyrophosphate metabolism and calcification in vascular smooth muscle.Catalytic signature of a heat-stable, chimeric human alkaline phosphatase with therapeutic potential.Rescue of severe infantile hypophosphatasia mice by AAV-mediated sustained expression of soluble alkaline phosphataseFunctional significance of calcium binding to tissue-nonspecific alkaline phosphatasePrevention of Lethal Murine Hypophosphatasia by Neonatal Ex Vivo Gene Therapy Using Lentivirally Transduced Bone Marrow CellsThe Functional co-operativity of Tissue-Nonspecific Alkaline Phosphatase (TNAP) and PHOSPHO1 during initiation of Skeletal Mineralization.Pharmacological inhibition of PHOSPHO1 suppresses vascular smooth muscle cell calcification.Alkaline Phosphatase and Hypophosphatasia.In vivo overexpression of tissue-nonspecific alkaline phosphatase increases skeletal mineralization and affects the phosphorylation status of osteopontinSkeletal Mineralization Deficits and Impaired Biogenesis and Function of Chondrocyte-Derived Matrix Vesicles in Phospho1(-/-) and Phospho1/Pi t1 Double-Knockout Mice.Compounded PHOSPHO1/ALPL deficiencies reduce dentin mineralizationTissue-nonspecific alkaline phosphatase acts redundantly with PAP and NT5E to generate adenosine in the dorsal spinal cord.Effects of pH on the production of phosphate and pyrophosphate by matrix vesicles' biomimetics.Proteoliposomes with the ability to transport Ca(2+) into the vesicles and hydrolyze phosphosubstrates on their surface.Proteoliposomes as matrix vesicles' biomimetics to study the initiation of skeletal mineralization.Effects of GPI-anchored TNAP on the dynamic structure of model membranes.Identification of altered brain metabolites associated with TNAP activity in a mouse model of hypophosphatasia using untargeted NMR-based metabolomics analysis.Zooming in on the genesis of atherosclerotic plaque microcalcifications.Highly potent and selective ectonucleotide pyrophosphatase/phosphodiesterase I inhibitors based on an adenosine 5'-(α or γ)-thio-(α,β- or β,γ)-methylenetriphosphate scaffold.Proteoliposomes in nanobiotechnology.The two sides of a lipid-protein story.Biophysical aspects of biomineralization.A multiphysics model of in vitro transcription coupling enzymatic reaction and precipitation formation.Thermodynamic properties and characterization of proteoliposomes rich in microdomains carrying alkaline phosphatase.Hypophosphatasia - pathophysiology and treatment.Matrix vesicles from chondrocytes and osteoblasts: Their biogenesis, properties, functions and biomimetic models.Mast Cell Mediators Inhibit Osteoblastic Differentiation and Extracellular Matrix Mineralization.
P2860
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P2860
Kinetic analysis of substrate utilization by native and TNAP-, NPP1-, or PHOSPHO1-deficient matrix vesicles
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Kinetic analysis of substrate ...... PHO1-deficient matrix vesicles
@ast
Kinetic analysis of substrate ...... PHO1-deficient matrix vesicles
@en
Kinetic analysis of substrate ...... PHO1-deficient matrix vesicles
@en-gb
Kinetic analysis of substrate ...... PHO1-deficient matrix vesicles
@nl
type
label
Kinetic analysis of substrate ...... PHO1-deficient matrix vesicles
@ast
Kinetic analysis of substrate ...... PHO1-deficient matrix vesicles
@en
Kinetic analysis of substrate ...... PHO1-deficient matrix vesicles
@en-gb
Kinetic analysis of substrate ...... PHO1-deficient matrix vesicles
@nl
prefLabel
Kinetic analysis of substrate ...... PHO1-deficient matrix vesicles
@ast
Kinetic analysis of substrate ...... PHO1-deficient matrix vesicles
@en
Kinetic analysis of substrate ...... PHO1-deficient matrix vesicles
@en-gb
Kinetic analysis of substrate ...... PHO1-deficient matrix vesicles
@nl
P2093
P2860
P921
P356
P1476
Kinetic analysis of substrate ...... PHO1-deficient matrix vesicles
@en
P2093
Ana Maria Sper Simão
Colin Farquharson
José Luis Millán
João Martins Pizauro
Manisha C Yadav
Marc F Hoylaerts
Pietro Ciancaglini
Sonoko Narisawa
P2860
P304
P356
10.1359/JBMR.091023
P407
P577
2010-04-01T00:00:00Z