The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.
about
Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochoresEvidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction.Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomesThe Zn finger protein Iguana impacts Hedgehog signaling by promoting ciliogenesisCSAP localizes to polyglutamylated microtubules and promotes proper cilia function and zebrafish developmentStable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3.The human kinetochore Ska1 complex facilitates microtubule depolymerization-coupled motilityIain Cheeseman: a strong attachment to kinetochores. [An interview by Ben Short]Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochoreKNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebratesFunctional genomics identifies a Myb domain-containing protein family required for assembly of CENP-A chromatinKNL1: bringing order to the kinetochoreCENP-T provides a structural platform for outer kinetochore assemblyStructure of human Mad1 C-terminal domain reveals its involvement in kinetochore targetingYeast Nkp2 is required for accurate chromosome segregation and interacts with several components of the central kinetochore.Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAKMolecular analysis of core kinetochore composition and assembly in Drosophila melanogasterDNA binding of centromere protein C (CENPC) is stabilized by single-stranded RNAIdentification of a predominant co-regulation among kinetochore genes, prospective regulatory elements, and association with genomic instabilityChromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientationCentromere identity, function, and epigenetic propagation across cell divisions.Dissection of CENP-C-directed centromere and kinetochore assemblyAurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly.Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochore.CaMtw1, a member of the evolutionarily conserved Mis12 kinetochore protein family, is required for efficient inner kinetochore assembly in the pathogenic yeast Candida albicans.The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.Hsp90-Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore-microtubule binding sites.Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program.Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cellsAurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface.Contrasting models for kinetochore microtubule attachment in mammalian cellsVertebrate kinetochore protein architecture: protein copy number.The life and miracles of kinetochores.The MIS12 complex is a protein interaction hub for outer kinetochore assembly.Molecular architecture and assembly of the yeast kinetochore MIND complex.Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology.Aurora B kinase controls the targeting of the Astrin-SKAP complex to bioriented kinetochores.Sos7, an essential component of the conserved Schizosaccharomyces pombe Ndc80-MIND-Spc7 complex, identifies a new family of fungal kinetochore proteinsMolecular architecture and connectivity of the budding yeast Mtw1 kinetochore complexDrosophila Mis12 complex acts as a single functional unit essential for anaphase chromosome movement and a robust spindle assembly checkpoint.
P2860
Q24293546-748F9E07-B724-4CE9-AD15-33B41740AA97Q24297396-097281B0-24FE-4B63-91D3-45901C5914DCQ24300684-4F3B4AC8-6A08-4E9D-BB5A-30758C0D4DA9Q24310161-BF0E7926-E0C7-4492-9185-889C310C0DB9Q24312744-D3770586-DBA9-43FE-B6FF-4EEE0C3BB45CQ24314703-5814A0FB-2579-44B9-80FF-29ECF6B82866Q24321815-DAA92174-ADD9-462B-AED7-50B37F2C7368Q24646049-A420FE1B-5978-4050-BCF2-2E08B52FCB7BQ24646882-114BBB3A-4CAE-4E92-A683-95A9D580D3A0Q24654035-9EA4DF97-0549-4899-A879-120E7C7142D1Q24683353-ED01AA12-8D63-4906-B6CC-A90E16C5E020Q27001042-24788344-730A-4F4A-900F-F6E7F815968AQ27675942-93E53830-7D44-471F-ACF4-A6CF374FA775Q27678430-A0D95070-D294-48D6-951C-7C2AC3871FA0Q27931764-74598EAC-420B-4617-A813-B09E50E72CA5Q28118830-C47C6F0B-66FD-431A-A0CD-A746094E06CCQ28469212-3F0F806C-3918-459A-BAB4-1324BE5D85B9Q28472760-51C3A358-B99E-4A60-9103-5DE7B7B7F763Q28477417-287422E9-0D9B-4456-ABAB-EB6162E2899CQ29871463-7A0E9CB4-90B0-41A6-8679-5EEA9189F764Q30427482-D7369F68-E31B-43E8-8736-D76766B9DE73Q30437632-3F3F9E98-5BF2-4927-93B5-F7FE142CB4EBQ30440998-72DCFF04-C6F5-4D15-9BCD-CE1BCA17583BQ30499448-6E87D4F8-A42C-4B3F-99BD-659ADA287E56Q30500057-5CC95678-4A39-4DC9-9E8A-4CB7EC58A887Q30529809-5646807A-96BE-4E91-B6C8-534F675906B1Q33799179-7535CB63-9630-43E7-91D6-BACD3CE3F253Q33811933-D8CA0607-1322-4BF5-AC9E-F0D3F852229CQ33816797-73A05A41-E648-43C3-B144-A962AE65AAC7Q33863228-48B301D2-A2E9-428B-8834-EBC1671001E2Q33905615-A417D131-6F95-464F-9C9C-6E49BB43FF4BQ33916069-C6BB6CE1-0526-4480-9A83-CFD64B8696FAQ34018608-2F0518D0-AB4C-4B95-9783-B8AAC3BA466FQ34111005-D5F384EE-5460-4A75-8984-D47CDBFE157CQ34111019-161B5BBB-438F-42A3-9935-E76BB6DB7DC3Q34199659-D66AB0ED-FB06-4E03-AA6A-55A1F455F7CDQ34218832-BD09AEEF-13BD-4EE8-8DA1-4DC8E16CCEF9Q34308636-09E03062-DF62-4187-ABFF-D8EDDEEC1CD9Q34474300-AA8B8CB6-974E-41F8-B77B-C64AFCABC505Q34477536-17C2FB93-638C-4CEC-9197-972F82AEE23C
P2860
The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The human Mis12 complex is req ...... proper chromosome segregation
@nl
The human Mis12 complex is req ...... proper chromosome segregation.
@ast
The human Mis12 complex is req ...... proper chromosome segregation.
@en
The human Mis12 complex is req ...... proper chromosome segregation.
@en-gb
type
label
The human Mis12 complex is req ...... proper chromosome segregation
@nl
The human Mis12 complex is req ...... proper chromosome segregation.
@ast
The human Mis12 complex is req ...... proper chromosome segregation.
@en
The human Mis12 complex is req ...... proper chromosome segregation.
@en-gb
prefLabel
The human Mis12 complex is req ...... proper chromosome segregation
@nl
The human Mis12 complex is req ...... proper chromosome segregation.
@ast
The human Mis12 complex is req ...... proper chromosome segregation.
@en
The human Mis12 complex is req ...... proper chromosome segregation.
@en-gb
P2093
P2860
P921
P3181
P356
P1476
The human Mis12 complex is req ...... proper chromosome segregation
@en
P2093
Arshad Desai
Susan L Kline
Tatsuo Fukagawa
Tetsuya Hori
P2860
P3181
P356
10.1083/JCB.200509158
P407
P577
2006-04-03T00:00:00Z