An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5-trisphosphate receptors
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Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasisProteomic analysis of detergent resistant membrane domains during early interaction of macrophages with rough and smooth Brucella melitensisThe Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavageBOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated DegradationMutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum-associated degradation pathwayTargeting β-tubulin:CCT-β complexes incurs Hsp90- and VCP-related protein degradation and induces ER stress-associated apoptosis by triggering capacitative Ca2+ entry, mitochondrial perturbation and caspase overactivation.Identification of commonly altered genes between in major depressive disorder and a mouse model of depression.Characterization of the C. elegans erlin homologue.ERLIN2 promotes breast cancer cell survival by modulating endoplasmic reticulum stress pathways.Activated inositol 1,4,5-trisphosphate receptors are modified by homogeneous Lys-48- and Lys-63-linked ubiquitin chains, but only Lys-48-linked chains are required for degradationRNF170 protein, an endoplasmic reticulum membrane ubiquitin ligase, mediates inositol 1,4,5-trisphosphate receptor ubiquitination and degradationAssociation of membrane rafts and postsynaptic density: proteomics, biochemical, and ultrastructural analyses.A nullimorphic ERLIN2 mutation defines a complicated hereditary spastic paraplegia locus (SPG18)Clustered hydrophobic amino acids in amphipathic helices mediate erlin1/2 complex assembly.A Point Mutation in the Ubiquitin Ligase RNF170 That Causes Autosomal Dominant Sensory Ataxia Destabilizes the Protein and Impairs Inositol 1,4,5-Trisphosphate Receptor-mediated Ca2+ SignalingRegulated Erlin-dependent release of the B12 transmembrane J-protein promotes ER membrane penetration of a non-enveloped virus.Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system.Activation of Ca(2+) -activated Cl(-) channel ANO1 by localized Ca(2+) signals.A novel ER-microtubule-binding protein, ERLIN2, stabilizes Cyclin B1 and regulates cell cycle progression.The mammalian endoplasmic reticulum-associated degradation systemEndoplasmic reticulum factor ERLIN2 regulates cytosolic lipid content in cancer cellsWhen worlds collide: IP(3) receptors and the ERAD pathway.Substrate-specific mediators of ER associated degradation (ERAD).SPFH1 and SPFH2 mediate the ubiquitination and degradation of inositol 1,4,5-trisphosphate receptors in muscarinic receptor-expressing HeLa cells.Oxidative protein folding in the endoplasmic reticulum: tight links to the mitochondria-associated membrane (MAM).Cellular pathways of hereditary spastic paraplegia.Inositol 1,4,5-trisphosphate receptors and their protein partners as signalling hubs.Membrane Protein Quantity Control at the Endoplasmic Reticulum.Identification of antibody-interacting proteins that contribute to the production of recombinant antibody in mammalian cells.∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.ITPR1 gene p.Val1553Met mutation in Russian family with mild Spinocerebellar ataxia.Contribution of Extracellular Matrix and Signal Mechanotransduction to Epithelial Cell Damage in Inflammatory Bowel Disease Patients: A Proteomic Study.
P2860
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P2860
An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5-trisphosphate receptors
description
2009 nî lūn-bûn
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2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2009 թվականի ապրիլին հրատարակված գիտական հոդված
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2009年の論文
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2009年論文
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2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
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name
An endoplasmic reticulum (ER) ...... 1,4,5-trisphosphate receptors
@ast
An endoplasmic reticulum (ER) ...... 1,4,5-trisphosphate receptors
@en
An endoplasmic reticulum (ER) ...... 1,4,5-trisphosphate receptors
@en-gb
An endoplasmic reticulum (ER) ...... 1,4,5-trisphosphate receptors
@nl
type
label
An endoplasmic reticulum (ER) ...... 1,4,5-trisphosphate receptors
@ast
An endoplasmic reticulum (ER) ...... 1,4,5-trisphosphate receptors
@en
An endoplasmic reticulum (ER) ...... 1,4,5-trisphosphate receptors
@en-gb
An endoplasmic reticulum (ER) ...... 1,4,5-trisphosphate receptors
@nl
prefLabel
An endoplasmic reticulum (ER) ...... 1,4,5-trisphosphate receptors
@ast
An endoplasmic reticulum (ER) ...... 1,4,5-trisphosphate receptors
@en
An endoplasmic reticulum (ER) ...... 1,4,5-trisphosphate receptors
@en-gb
An endoplasmic reticulum (ER) ...... 1,4,5-trisphosphate receptors
@nl
P2093
P2860
P921
P356
P1476
An endoplasmic reticulum (ER) ...... 1,4,5-trisphosphate receptors
@en
P2093
Duncan B Wormer
Margaret M P Pearce
Richard J H Wojcikiewicz
Stephan Wilkens
P2860
P304
P356
10.1074/JBC.M809801200
P407
P577
2009-04-17T00:00:00Z