Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen-induced arthritis
about
Endoplasmic reticulum stress and Parkinson's disease: the role of HRD1 in averting apoptosis in neurodegenerative diseaseHrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosisAntiviral activity of a small molecule deubiquitinase inhibitor occurs via induction of the unfolded protein responseIcariin induces synoviolin expression through NFE2L1 to protect neurons from ER stress-induced apoptosisAn E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid beta-proteinE3 ubiquitin ligase synoviolin is involved in liver fibrogenesisUbiquitin ligase SYVN1/HRD1 facilitates degradation of the SERPINA1 Z variant/α-1-antitrypsin Z variant via SQSTM1/p62-dependent selective autophagy.sel-11 and cdc-42, two negative modulators of LIN-12/Notch activity in C. elegansSynoviocyte-derived angiopoietin-like protein 2 contributes to synovial chronic inflammation in rheumatoid arthritisAutophagy induction and CHOP under-expression promotes survival of fibroblasts from rheumatoid arthritis patients under endoplasmic reticulum stressUbiquitination of inositol-requiring enzyme 1 (IRE1) by the E3 ligase CHIP mediates the IRE1/TRAF2/JNK pathway.Hrd1-mediated BLIMP-1 ubiquitination promotes dendritic cell MHCII expression for CD4 T cell priming during inflammation.Cytomegalovirus downregulates IRE1 to repress the unfolded protein response.Toxoplasma gondii prevalent in China induce weaker apoptosis of neural stem cells C17.2 via endoplasmic reticulum stress (ERS) signaling pathways.UPR, autophagy, and mitochondria crosstalk underlies the ER stress responseThe ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity.A Ubc7p-binding domain in Cue1p activates ER-associated protein degradation.Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell immunity through degradation of the death receptor CD95/FasIRE1: ER stress sensor and cell fate executor.Role of GRP78/BiP degradation and ER stress in deoxynivalenol-induced interleukin-6 upregulation in the macrophage.Endoplasmic reticulum and the unfolded protein response: dynamics and metabolic integrationLoss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway.Cell-type variation in stress responses as a consequence of manipulating GRP78 expression in neuroectodermal cells.Hrd1 participates in the regulation of collagen I synthesis in renal fibrosis.New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation.Constitutive CD40 Signaling Calibrates Differentiation Outcomes in Responding B Cells via Multiple Molecular Pathways.Protective role of Gipie, a Girdin family protein, in endoplasmic reticulum stress responses in endothelial cells.Overexpression of synoviolin facilitates the formation of a functional synovial biomembrane.RING-finger type E3 ubiquitin ligase inhibitors as novel candidates for the treatment of rheumatoid arthritis.Human Coronaviruses: A Review of Virus-Host Interactions.Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis.Inhibition of IRE1α-mediated XBP1 mRNA cleavage by XBP1 reveals a novel regulatory process during the unfolded protein response.Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4.ERβ decreases breast cancer cell survival by regulating the IRE1/XBP-1 pathway.The Selective Autophagy Receptor Optineurin in Crohn's Disease.IRE1α Implications in Endoplasmic Reticulum Stress-Mediated Development and Pathogenesis of Autoimmune Diseases.ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes
P2860
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P2860
Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen-induced arthritis
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Synoviolin promotes IRE1 ubiqu ...... ith collagen-induced arthritis
@ast
Synoviolin promotes IRE1 ubiqu ...... ith collagen-induced arthritis
@en
Synoviolin promotes IRE1 ubiqu ...... ith collagen-induced arthritis
@en-gb
Synoviolin promotes IRE1 ubiqu ...... ith collagen-induced arthritis
@nl
type
label
Synoviolin promotes IRE1 ubiqu ...... ith collagen-induced arthritis
@ast
Synoviolin promotes IRE1 ubiqu ...... ith collagen-induced arthritis
@en
Synoviolin promotes IRE1 ubiqu ...... ith collagen-induced arthritis
@en-gb
Synoviolin promotes IRE1 ubiqu ...... ith collagen-induced arthritis
@nl
prefLabel
Synoviolin promotes IRE1 ubiqu ...... ith collagen-induced arthritis
@ast
Synoviolin promotes IRE1 ubiqu ...... ith collagen-induced arthritis
@en
Synoviolin promotes IRE1 ubiqu ...... ith collagen-induced arthritis
@en-gb
Synoviolin promotes IRE1 ubiqu ...... ith collagen-induced arthritis
@nl
P2093
P2860
P3181
P356
P1433
P1476
Synoviolin promotes IRE1 ubiqu ...... ith collagen-induced arthritis
@en
P2093
Beixue Gao
Donna D Zhang
Jinping Zhang
Krishnaswamy Kannan
Robert A Ortmann
Sang-Myeong Lee
P2860
P3181
P356
10.1038/EMBOR.2008.37
P407
P577
2008-05-01T00:00:00Z