Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and can be rescued by autosomal recessive Parkinson disease genes, Parkin or DJ-1
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The role of oxidative stress in Parkinson's diseaseEvaluation of Models of Parkinson's DiseaseParkinson's disease: animal models and dopaminergic cell vulnerabilityBehavioral phenotyping of Parkin-deficient mice: looking for early preclinical features of Parkinson's diseaseImpaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary diseaseTrib3 Is Elevated in Parkinson's Disease and Mediates Death in Parkinson's Disease Models.Methyl-Arginine Profile of Brain from Aged PINK1-KO+A53T-SNCA Mice Suggests Altered Mitochondrial Biogenesis.TRAP1 rescues PINK1 loss-of-function phenotypes.PINK1 deficiency enhances autophagy and mitophagy inductionParkinson's disease and enhanced inflammatory response.PINK1 as a molecular checkpoint in the maintenance of mitochondrial function and integrityMitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences.Defective autophagy in Parkinson's disease: lessons from genetics.The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans.The Effects of Variants in the Parkin, PINK1, and DJ-1 Genes along with Evidence for their Pathogenicity.The mitochondrial kinase PINK1: functions beyond mitophagy.Gene therapy targeting mitochondrial pathway in Parkinson's disease.PINK1 in the limelight: multiple functions of an eclectic protein in human health and disease.The effects of morphine on Parkinson's-related genes PINK1 and PARK2.Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease.Upregulation of autophagy-related gene 5 protects dopaminergic neurons in a zebrafish model of Parkinson's disease.Neurotoxin mechanisms and processes relevant to Parkinson's disease: an update.α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism.DJ-1/PARK7, But Not Its L166P Mutant Linked to Autosomal Recessive Parkinsonism, Modulates the Transcriptional Activity of the Orphan Nuclear Receptor Nurr1 In Vitro and In Vivo.Parkin-knockout mice did not display increased vulnerability to intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).Comparative analysis of Parkinson's disease-associated genes reveals altered survival and bioenergetics of parkin-deficient dopamine neurons in mice.Cellular and Molecular Basis of Neurodegeneration in Parkinson Disease.
P2860
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P2860
Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and can be rescued by autosomal recessive Parkinson disease genes, Parkin or DJ-1
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Inactivation of Pink1 gene in ...... disease genes, Parkin or DJ-1
@ast
Inactivation of Pink1 gene in ...... disease genes, Parkin or DJ-1
@en
Inactivation of Pink1 gene in ...... disease genes, Parkin or DJ-1
@en-gb
Inactivation of Pink1 gene in ...... disease genes, Parkin or DJ-1
@nl
type
label
Inactivation of Pink1 gene in ...... disease genes, Parkin or DJ-1
@ast
Inactivation of Pink1 gene in ...... disease genes, Parkin or DJ-1
@en
Inactivation of Pink1 gene in ...... disease genes, Parkin or DJ-1
@en-gb
Inactivation of Pink1 gene in ...... disease genes, Parkin or DJ-1
@nl
prefLabel
Inactivation of Pink1 gene in ...... disease genes, Parkin or DJ-1
@ast
Inactivation of Pink1 gene in ...... disease genes, Parkin or DJ-1
@en
Inactivation of Pink1 gene in ...... disease genes, Parkin or DJ-1
@en-gb
Inactivation of Pink1 gene in ...... disease genes, Parkin or DJ-1
@nl
P2093
P2860
P921
P356
P1476
Inactivation of Pink1 gene in ...... disease genes, Parkin or DJ-1
@en
P2093
Chantal Mazerolle
David S Park
Elizabeth Abdel-Messih
Farzaneh Safarpour
Hymie Anisman
M Emdadul Haque
Matthew P Mount
Ruth S Slack
Steve Callaghan
P2860
P304
P356
10.1074/JBC.M112.346437
P407
P577
2012-06-29T00:00:00Z