Tip60 and p400 are both required for UV-induced apoptosis but play antagonistic roles in cell cycle progression.
about
The histidine triad protein Hint1 triggers apoptosis independent of its enzymatic activityDNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamicsBRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51.Tip60 histone acetyltransferase acts as a negative regulator of Notch1 signaling by means of acetylationA novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targetsRVBs are required for assembling a functional TIP60 complexHuman Rvb1/Tip49 is required for the histone acetyltransferase activity of Tip60/NuA4 and for the downregulation of phosphorylation on H2AX after DNA damage.Analysis of Myc-induced histone modifications on target chromatin.The E1A-associated p400 protein modulates cell fate decisions by the regulation of ROS homeostasis.Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expressionCohesin protects genes against γH2AX Induced by DNA double-strand breaks.Essential role of p400/mDomino chromatin-remodeling ATPase in bone marrow hematopoiesis and cell-cycle progressionActivation of p21 by HDAC inhibitors requires acetylation of H2A.Z.Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53p21 transcription is regulated by differential localization of histone H2A.Z.EP400 Deposits H3.3 into Promoters and Enhancers during Gene ActivationThe chromatin remodeler p400 ATPase facilitates Rad51-mediated repair of DNA double-strand breaks.Connecting chromatin modifying factors to DNA damage response.Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing.The Stress-responsive Gene ATF3 Mediates Dichotomous UV Responses by Regulating the Tip60 and p53 Proteins.The MYST family of histone acetyltransferases and their intimate links to cancer.PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosisC19MC microRNAs are processed from introns of large Pol-II, non-protein-coding transcripts.Regulation of gene expression and cellular proliferation by histone H2A.Z.Regulation of p53 tumour suppressor target gene expression by the p52 NF-kappaB subunit.PIASy-mediated Tip60 sumoylation regulates p53-induced autophagy.High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome.The SANT domain of p400 ATPase represses acetyltransferase activity and coactivator function of TIP60 in basal p21 gene expressionPhysical interaction between the histone acetyl transferase Tip60 and the DNA double-strand breaks sensor MRN complex.BRCA1 and Tip60 determine the cellular response to ultraviolet irradiation through distinct pathwaysPML involvement in the p73-mediated E1A-induced suppression of EGFR and induction of apoptosis in head and neck cancers.p400 function is required for the adenovirus E1A-mediated suppression of EGFR and tumour cell killing.Chromatin regulation Tip(60)s the balance in embryonic stem cell self-renewalGlycogen synthase kinase 3beta phosphorylates p21WAF1/CIP1 for proteasomal degradation after UV irradiation.Loss of the chromatin regulator MRG15 limits neural stem/progenitor cell proliferation via increased expression of the p21 Cdk inhibitor.Regulation of CBP and Tip60 coordinates histone acetylation at local and global levels during Ras-induced transformation.Cleavage and cytoplasmic relocalization of histone deacetylase 3 are important for apoptosis progression.Acetylation of the p53 DNA-binding domain regulates apoptosis induction.The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways.Critical role of the p400/mDomino chromatin-remodeling ATPase in embryonic hematopoiesis.
P2860
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P2860
Tip60 and p400 are both required for UV-induced apoptosis but play antagonistic roles in cell cycle progression.
description
2006 nî lūn-bûn
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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Tip60 and p400 are both requir ...... oles in cell cycle progression
@nl
Tip60 and p400 are both requir ...... les in cell cycle progression.
@ast
Tip60 and p400 are both requir ...... les in cell cycle progression.
@en
Tip60 and p400 are both requir ...... les in cell cycle progression.
@en-gb
type
label
Tip60 and p400 are both requir ...... oles in cell cycle progression
@nl
Tip60 and p400 are both requir ...... les in cell cycle progression.
@ast
Tip60 and p400 are both requir ...... les in cell cycle progression.
@en
Tip60 and p400 are both requir ...... les in cell cycle progression.
@en-gb
prefLabel
Tip60 and p400 are both requir ...... oles in cell cycle progression
@nl
Tip60 and p400 are both requir ...... les in cell cycle progression.
@ast
Tip60 and p400 are both requir ...... les in cell cycle progression.
@en
Tip60 and p400 are both requir ...... les in cell cycle progression.
@en-gb
P2093
P2860
P356
P1433
P1476
Tip60 and p400 are both requir ...... les in cell cycle progression.
@en
P2093
Gaëlle Legube
Marie Vandromme
Martine Chevillard-Briet
Sandrine Tyteca
P2860
P304
P356
10.1038/SJ.EMBOJ.7601066
P407
P577
2006-04-06T00:00:00Z