BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2
about
CD74 interacts with APP and suppresses the production of AbetaAPP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesicles functionsDeletion of the γ-secretase subunits Aph1B/C impairs memory and worsens the deficits of knock-in mice modeling the Alzheimer-like familial Danish dementiaGeneration and initial characterization of FDD knock in miceAltering APP proteolysis: increasing sAPPalpha production by targeting dimerization of the APP ectodomainDanish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficitsMemory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis.Identification of NEEP21 as a ß-amyloid precursor protein-interacting protein in vivo that modulates amyloidogenic processing in vitro.APP and APLP2 interact with the synaptic release machinery and facilitate transmitter release at hippocampal synapses.BRI2 interacts with BACE1 and regulates its cellular levels by promoting its degradation and reducing its mRNA levels.Structural and functional alterations in amyloid-β precursor protein induced by amyloid-β peptides.BRICHOS domain associated with lung fibrosis, dementia and cancer--a chaperone that prevents amyloid fibril formation?Therapeutic uses of furin and its inhibitors: a patent review.A Greek Tragedy: The Growing Complexity of Alzheimer Amyloid Precursor Protein Proteolysis.Not just amyloid: physiological functions of the amyloid precursor protein family.Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and NeurodegenerationMicroRNA-323 regulates ischemia/reperfusion injury-induced neuronal cell death by targeting BRI3.Alzheimer disease: modeling an Aβ-centered biological network.Potential Role of Long Non-Coding RNA ANRIL in Pediatric Medulloblastoma Through Promotion on Proliferation and Migration by Targeting miR-323.Clptm1 Limits Forward Trafficking of GABAA Receptors to Scale Inhibitory Synaptic Strength.
P2860
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P2860
BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
BRI3 inhibits amyloid precurso ...... s homologue dementia gene BRI2
@ast
BRI3 inhibits amyloid precurso ...... s homologue dementia gene BRI2
@en
BRI3 inhibits amyloid precurso ...... s homologue dementia gene BRI2
@en-gb
BRI3 inhibits amyloid precurso ...... s homologue dementia gene BRI2
@nl
type
label
BRI3 inhibits amyloid precurso ...... s homologue dementia gene BRI2
@ast
BRI3 inhibits amyloid precurso ...... s homologue dementia gene BRI2
@en
BRI3 inhibits amyloid precurso ...... s homologue dementia gene BRI2
@en-gb
BRI3 inhibits amyloid precurso ...... s homologue dementia gene BRI2
@nl
prefLabel
BRI3 inhibits amyloid precurso ...... s homologue dementia gene BRI2
@ast
BRI3 inhibits amyloid precurso ...... s homologue dementia gene BRI2
@en
BRI3 inhibits amyloid precurso ...... s homologue dementia gene BRI2
@en-gb
BRI3 inhibits amyloid precurso ...... s homologue dementia gene BRI2
@nl
P2860
P356
P1476
BRI3 inhibits amyloid precurso ...... s homologue dementia gene BRI2
@en
P2093
Shuji Matsuda
Yukiko Matsuda
P2860
P304
15815-15825
P356
10.1074/JBC.M109.006403
P407
P577
2009-04-14T00:00:00Z