Interference with the expression of a novel human polycomb protein, hPc2, results in cellular transformation and apoptosis
about
RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programsBypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locusThe SUMO E3 ligase activity of Pc2 is coordinated through a SUMO interaction motifThe core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans.Characterization of interactions between the mammalian polycomb-group proteins Enx1/EZH2 and EED suggests the existence of different mammalian polycomb-group protein complexes.Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cellsSelective interactions between vertebrate polycomb homologs and the SUV39H1 histone lysine methyltransferase suggest that histone H3-K9 methylation contributes to chromosomal targeting of Polycomb group proteins.The polycomb group protein EED interacts with YY1, and both proteins induce neural tissue in Xenopus embryosC-Terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate Polycomb proteinsRING1 interacts with multiple Polycomb-group proteins and displays tumorigenic activityMLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding proteinA role for non-covalent SUMO interaction motifs in Pc2/CBX4 E3 activity.HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression propertiesIdentification and analysis of chromodomain-containing proteins encoded in the mouse transcriptomePolycomb CBX7 has a unifying role in cellular lifespanCoordinated histone modifications mediated by a CtBP co-repressor complexThe ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3SUMO and Chromatin Remodeling.Inhibition of CtBP1 activity by Akt-mediated phosphorylation.Multiple activities contribute to Pc2 E3 function.Human polycomb 2 protein is a SUMO E3 ligase and alleviates substrate-induced inhibition of cystathionine beta-synthase sumoylation.Novel motifs distinguish multiple homologues of Polycomb in vertebrates: expansion and diversification of the epigenetic toolkitProteomic analysis of EZH2 downstream target proteins in hepatocellular carcinoma.Chromobox homolog 2 protein: A novel biomarker for predicting prognosis and Taxol sensitivity in patients with breast cancer.Transcriptional repression by XPc1, a new Polycomb homolog in Xenopus laevis embryos, is independent of histone deacetylaseMultiple Arkadia/RNF111 structures coordinate its Polycomb body association and transcriptional control.Polycomb group-dependent Cyclin A repression in DrosophilaMaintenance of gene expression patterns.An integrated approach to uncover drivers of cancer.Increased expression of the EZH2 polycomb group gene in BMI-1-positive neoplastic cells during bronchial carcinogenesis.Role of polycomb group proteins in the DNA damage response--a reassessment.Tough beginnings: alterations in the transcriptome of cloned embryos during the first two cell cyclesCoexpression of BMI-1 and EZH2 polycomb group genes in Reed-Sternberg cells of Hodgkin's disease.Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome.The polycomb group proteins, BMI-1 and EZH2, are tumour-associated antigensLow BMI-1 expression is associated with an activated BMI-1-driven signature, vascular invasion, and hormone receptor loss in endometrial carcinoma.Contribution of CBX4 to cumulus oophorus cell phenotype in mice and attendant effects in cumulus cell cloned embryosGene silencing by the Polycomb group proteins and associations with cancer.New insights into MLL gene rearranged acute leukemias using gene expression profiling: shared pathways, lineage commitment, and partner genes.
P2860
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P2860
Interference with the expression of a novel human polycomb protein, hPc2, results in cellular transformation and apoptosis
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Interference with the expressi ...... r transformation and apoptosis
@ast
Interference with the expressi ...... r transformation and apoptosis
@en
Interference with the expressi ...... r transformation and apoptosis
@en-gb
Interference with the expressi ...... r transformation and apoptosis
@nl
type
label
Interference with the expressi ...... r transformation and apoptosis
@ast
Interference with the expressi ...... r transformation and apoptosis
@en
Interference with the expressi ...... r transformation and apoptosis
@en-gb
Interference with the expressi ...... r transformation and apoptosis
@nl
prefLabel
Interference with the expressi ...... r transformation and apoptosis
@ast
Interference with the expressi ...... r transformation and apoptosis
@en
Interference with the expressi ...... r transformation and apoptosis
@en-gb
Interference with the expressi ...... r transformation and apoptosis
@nl
P2093
P2860
P921
P356
P1476
Interference with the expressi ...... r transformation and apoptosis
@en
P2093
C Lambrechts
D P Satijn
H Masselink
J van der Vlag
M J Gunster
R G Sewalt
R van Driel
P2860
P304
P356
10.1128/MCB.17.10.6076
P407
P577
1997-10-01T00:00:00Z