A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
about
C16orf57, a gene mutated in poikiloderma with neutropenia, encodes a putative phosphodiesterase responsible for the U6 snRNA 3' end modificationThe poly A polymerase Star-PAP controls 3'-end cleavage by promoting CPSF interaction and specificity toward the pre-mRNAInositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylationCKIalpha is associated with and phosphorylates star-PAP and is also required for expression of select star-PAP target messenger RNAsStructural basis for dimerization and activity of human PAPD1, a noncanonical poly(A) polymerasemRNA 3'end processing: A tale of the tail reaches the clinicSequence context outside the target region influences the effectiveness of miR-223 target sites in the RhoB 3'UTRPhosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell ActivationNuclear PI3K signaling in cell growth and tumorigenesisControl of poly(A) tail lengthPoly(A) polymerase (PAP) diversity in gene expression--star-PAP vs canonical PAPPhosphoinositides: tiny lipids with giant impact on cell regulationMolecular Basis for Association of PIPKI -p90 with Clathrin Adaptor AP-2Structure of the Mitochondrial Editosome-Like Complex Associated TUTase 1 Reveals Divergent Mechanisms of UTP Selection and Domain OrganizationCrystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivityPIP kinases define PI4,5P₂signaling specificity by association with effectorsEmerging roles of PtdIns(4,5)P2--beyond the plasma membranePhosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brainLAPTM4B is a PtdIns(4,5)P2 effector that regulates EGFR signaling, lysosomal sorting, and degradation.Fibrillarin methylates H2A in RNA polymerase I trans-active promoters in Brassica oleracea.Nuclear phosphoinositides: a signaling enigma wrapped in a compartmental conundrum.New perspectives on the diversification of the RNA interference system: insights from comparative genomics and small RNA sequencing.Molecular mechanisms of eukaryotic pre-mRNA 3' end processing regulation.Nuclear pre-mRNA 3'-end processing regulates synapse and axon development in C. elegans.A comprehensive survey of 3' animal miRNA modification events and a possible role for 3' adenylation in modulating miRNA targeting effectiveness.Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexityPhosphatidylinositol 4-phosphate 5-kinase α negatively regulates nerve growth factor-induced neurite outgrowth in PC12 cells.Phosphatidylinositol 4,5-bisphosphate: targeted production and signalingSpecificity factors in cytoplasmic polyadenylationActin dynamics is rapidly regulated by the PTEN and PIP2 signaling pathways leading to myocyte hypertrophy.The human TUT1 nucleotidyl transferase as a global regulator of microRNA abundanceCPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translationPhosphoinositide signaling: new tools and insights.The ribonucleotidyl transferase USIP-1 acts with SART3 to promote U6 snRNA recycling.CKI isoforms α and ε regulate Star-PAP target messages by controlling Star-PAP poly(A) polymerase activity and phosphoinositide stimulation.An inside-out origin for the eukaryotic cell.Inositol phosphate pathway controls transcription of telomeric expression sites in trypanosomes.Star-PAP control of BIK expression and apoptosis is regulated by nuclear PIPKIα and PKCδ signaling.Genome-Wide Analysis of PAPS1-Dependent Polyadenylation Identifies Novel Roles for Functionally Specialized Poly(A) Polymerases in Arabidopsis thaliana.A novel gene expression pathway regulated by nuclear phosphoinositides
P2860
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P248
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P2860
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
@ast
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
@en
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
@en-gb
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
@nl
type
label
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
@ast
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
@en
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
@en-gb
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
@nl
prefLabel
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
@ast
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
@en
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
@en-gb
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
@nl
P2093
P2860
P921
P3181
P356
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P1476
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
@en
P2093
Christina Kendziorski
Chunhua Song
David L Mellman
Michael L Gonzales
P2860
P2888
P304
P3181
P356
10.1038/NATURE06666
P407
P577
2008-02-01T00:00:00Z
P5875
P6179
1041120380