Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
about
Emerging roles of nodal and Cripto-1: from embryogenesis to breast cancer progressionActivins and activin antagonists in hepatocellular carcinomaLefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptorsHuman Cerberus prevents nodal-receptor binding, inhibits nodal signaling, and suppresses nodal-mediated phenotypesGRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growthRegulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signalingCripto-1 overexpression is involved in the tumorigenesis of nasopharyngeal carcinoma.Cripto-1 acts as a functional marker of cancer stem-like cells and predicts prognosis of the patients in esophageal squamous cell carcinomaA small synthetic cripto blocking Peptide improves neural induction, dopaminergic differentiation, and functional integration of mouse embryonic stem cells in a rat model of Parkinson's disease.Cripto haploinsufficiency affects in vivo colon tumor developmentActivin/Nodal signalling before implantation: setting the stage for embryo patterning.MicroRNA-centric measurement improves functional enrichment analysis of co-expressed and differentially expressed microRNA clustersTargeting Nodal in malignant melanoma cells.Targeting the embryonic gene Cripto-1 in cancer and beyond.Cripto-1 is a cell surface marker for a tumorigenic, undifferentiated subpopulation in human embryonal carcinoma cells.Characterization of the glycosylphosphatidylinositol-anchor signal sequence of human Cryptic with a hydrophilic extension.Structural insights into the interaction between the Cripto CFC domain and the ALK4 receptor.Genetic variants modulating CRIPTO serum levels identified by genome-wide association study in Cilento isolatesOverexpression of human Cripto-1 in transgenic mice delays mammary gland development and differentiation and induces mammary tumorigenesisDecrypting the role of Cripto in tumorigenesisExpression and functional role of CRIPTO-1 in cutaneous melanoma.Role of Cripto-1 during epithelial-to-mesenchymal transition in development and cancer.Cripto as a target for cancer immunotherapy.Engineering a dopaminergic phenotype in stem/precursor cells: role of Nurr1, glia-derived signals, and Wnts.Nodal-dependant Cripto signaling in ES cells: from stem cells to tumor biology.Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis.Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin.Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction.Effects of a novel Nodal-targeting monoclonal antibody in melanomaRegulation of Cripto-1 signaling and biological activity by caveolin-1 in mammary epithelial cellsAnti-Cripto Mab inhibit tumour growth and overcome MDR in a human leukaemia MDR cell line by inhibition of Akt and activation of JNK/SAPK and bad death pathways.Cripto/GRP78 modulation of the TGF-β pathway in development and oncogenesisActivin signaling as an emerging target for therapeutic interventionsBlockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways.Clinicopathological and biological significance of cripto overexpression in human colon cancerCripto-1 is required for hypoxia to induce cardiac differentiation of mouse embryonic stem cells.Age-Dependent Association between Protein Expression of the Embryonic Stem Cell Marker Cripto-1 and Survival of Glioblastoma Patients.Human Cripto-1 as a target for a cancer vaccine: WO2008040759.The role of activin in mammary gland development and oncogenesis.Targeting the tumor microenvironment by immunotherapy: part 2.
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P2860
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
@ast
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
@en
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
@en-gb
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
@nl
type
label
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
@ast
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
@en
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
@en-gb
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
@nl
prefLabel
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
@ast
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
@en
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
@en-gb
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
@nl
P2093
P2860
P356
P1476
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
@en
P2093
Anne E Cheung
Antonella De Luca
Caterina Bianco
Chris Benjamin
David Salomon
Dian Olson
Doreen LePage
Heather B Adkins
Kevin P Williams
Konrad Miatkowski
P2860
P304
P356
10.1172/JCI17788
P407
P577
2003-08-01T00:00:00Z