Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis
about
Evidence for interaction between human PRUNE and nm23-H1 NDPKinaseA novel human nucleoside diphosphate (NDP) kinase, Nm23-H6, localizes in mitochondria and affects cytokinesisIntegrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagementNuclear translocation of integrin cytoplasmic domain-associated protein 1 stimulates cellular proliferation.NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-beta (TGF-beta) receptor-interacting protein, and negatively regulates TGF-beta signalingA new human nm23 homologue (nm23-H5) specifically expressed in testis germinal cellsThe nucleoside diphosphate kinase of human neutrophilsDirect evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcriptionAnalysis of differential gene expression by display of 3' end restriction fragments of cDNAsThe Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: characterizing a new regulatory motifTIP30 has an intrinsic kinase activity required for up-regulation of a subset of apoptotic genesAdenylate kinase complements nucleoside diphosphate kinase deficiency in nucleotide metabolismHeterogeneous nuclear ribonucleoprotein K is a transcription factorMetastases suppressor NM23-H2 interaction with G-quadruplex DNA within c-MYC promoter nuclease hypersensitive element induces c-MYC expressionNme protein family evolutionary history, a vertebrate perspectiveInteraction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulationMolecular biology of breast cancer metastasis. Genetic regulation of human breast carcinoma metastasis.Nucleoside diphosphate kinase from Mycobacterium tuberculosis cleaves single strand DNA within the human c-myc promoter in an enzyme-catalyzed reactionDespite WT1 binding sites in the promoter region of human and mouse nucleoporin glycoprotein 210, WT1 does not influence expression of GP210Classification between normal and tumor tissues based on the pair-wise gene expression ratioThe distribution of SNPs in human gene regulatory regionsThe human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinaseNM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III1Nucleoside diphosphate kinase. Investigation of the intersubunit contacts by site-directed mutagenesis and crystallography3'-Phosphorylated nucleotides are tight binding inhibitors of nucleoside diphosphate kinase activityNucleoside diphosphate kinase of Saccharomyces cerevisiae, Ynk1p: localization to the mitochondrial intermembrane space.Structural and catalytic properties and homology modelling of the human nucleoside diphosphate kinase C, product of the DRnm23 geneNeuroblastoma specific effects of DR-nm23 and its mutant forms on differentiation and apoptosisDNA tetraplex formation in the control region of c-mycThe transcription factor, Nm23H2, binds to and activates the translocated c-myc allele in Burkitt's lymphomaHeat stress response in pea involves interaction of mitochondrial nucleoside diphosphate kinase with a novel 86-kilodalton proteinMultiple functions of Nm23-H1 are regulated by oxido-reduction systemNm23-M5 mediates round and elongated spermatid survival by regulating GPX-5 levelsA Proteomics Approach to Investigate miR-153-3p and miR-205-5p Targets in Neuroblastoma CellsOverexpression of nucleoside diphosphate kinases induces neurite outgrowth and their substitution to inactive forms leads to suppression of nerve growth factor- and dibutyryl cyclic AMP-induced effects in PC12D cellsA new function of Nm23/NDP kinase as a differentiation inhibitory factor, which does not require it's kinase activityTumour metastasis suppressor, nm23-beta, inhibits gelatinase A transcription by interference with transactivator Y-box protein-1 (YB-1)Interaction of nucleoside diphosphate kinase and catalases for stress and light responses in Neurospora crassaPuF, an antimetastatic and developmental signaling protein, interacts with the Alzheimer's amyloid-β precursor protein via a tissue-specific proximal regulatory element (PRE)Copurification of vimentin, energy metabolism enzymes, and a MER5 homolog with nucleoside diphosphate kinase. Identification of tissue-specific interactions.
P2860
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P2860
Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis
description
1993 nî lūn-bûn
@nan
1993 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
name
Human c-myc transcription fact ...... suppressor of tumor metastasis
@ast
Human c-myc transcription fact ...... suppressor of tumor metastasis
@en
Human c-myc transcription fact ...... suppressor of tumor metastasis
@en-gb
Human c-myc transcription fact ...... suppressor of tumor metastasis
@nl
type
label
Human c-myc transcription fact ...... suppressor of tumor metastasis
@ast
Human c-myc transcription fact ...... suppressor of tumor metastasis
@en
Human c-myc transcription fact ...... suppressor of tumor metastasis
@en-gb
Human c-myc transcription fact ...... suppressor of tumor metastasis
@nl
prefLabel
Human c-myc transcription fact ...... suppressor of tumor metastasis
@ast
Human c-myc transcription fact ...... suppressor of tumor metastasis
@en
Human c-myc transcription fact ...... suppressor of tumor metastasis
@en-gb
Human c-myc transcription fact ...... suppressor of tumor metastasis
@nl
P2093
P356
P1433
P1476
Human c-myc transcription fact ...... suppressor of tumor metastasis
@en
P2093
C A Ferrone
E H Postel
S J Berberich
P304
P356
10.1126/SCIENCE.8392752
P407
P577
1993-07-23T00:00:00Z