G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth
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A deletion in exon 9 of the LIPH gene is responsible for the rex hair coat phenotype in rabbits (Oryctolagus cuniculus)Autosomal-dominant woolly hair resulting from disruption of keratin 74 (KRT74), a potential determinant of human hair textureMutations in SNRPE, which encodes a core protein of the spliceosome, cause autosomal-dominant hypotrichosis simplexAPCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplexInternational Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligandsLipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assayIdentification and characterization of a novel lysophosphatidic acid receptor, p2y5/LPA6Recent advances in targeting the autotaxin-lysophosphatidate-lipid phosphate phosphatase axis in vivoG-Protein-Coupled Lysophosphatidic Acid Receptors and Their Regulation of AKT SignalingLysophospholipids and their receptors in the central nervous systemLipid phosphate phosphatase (LPP3) and vascular developmentRole of the autotaxin-lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapyRegulation of T cell motility in vitro and in vivo by LPA and LPA2Lysophospholipid receptors LPA1–3 are not required for the inhibitory effects of LPA on mouse retinal growth conesLysophospholipid receptors in drug discovery.Phospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizationsInternational Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂Lysophosphatidate induces chemo-resistance by releasing breast cancer cells from taxol-induced mitotic arrestHighly prevalent LIPH founder mutations causing autosomal recessive woolly hair/hypotrichosis in Japan and the genotype/phenotype correlationsHigher LPA2 and LPA6 mRNA Levels in Hepatocellular Carcinoma Are Associated with Poorer Differentiation, Microvascular Invasion and Earlier Recurrence with Higher Serum Autotaxin LevelsA novel homozygous variant in the dsp gene underlies the first case of non-syndromic form of alopecia.Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors.International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature.Inhibition of autotaxin production or activity blocks lysophosphatidylcholine-induced migration of human breast cancer and melanoma cellsRole of LPA4/p2y9/GPR23 in negative regulation of cell motilityThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsRho/ROCK pathway is essential to the expansion, differentiation, and morphological rearrangements of human neural stem/progenitor cells induced by lysophosphatidic acidEvaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device.Multiple actions of lysophosphatidic acid on fibroblasts revealed by transcriptional profiling2D binary QSAR modeling of LPA3 receptor antagonism.Differential requirement of the epidermal growth factor receptor for G protein-mediated activation of transcription factors by lysophosphatidic acid.Lysophosphatidic acid (LPA) signaling in vertebrate reproduction.Altered lysophosphatidic acid (LPA) receptor expression during hepatic regeneration in a mouse model of partial hepatectomyLysophosphatidic acid (LPA) receptors: signaling properties and disease relevance.Founder mutations in the lipase h gene in families with autosomal recessive woolly hair/hypotrichosisLPA receptor signaling: pharmacology, physiology, and pathophysiology.Requirement of Osteopontin in the migration and protection against Taxol-induced apoptosis via the ATX-LPA axis in SGC7901 cells.LPA5 is abundantly expressed by human mast cells and important for lysophosphatidic acid induced MIP-1β releasePharmacological characterization of GPR55, a putative cannabinoid receptorThe effect of inbreeding on the distribution of compound heterozygotes: a lesson from Lipase H mutations in autosomal recessive woolly hair/hypotrichosis
P2860
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P2860
G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
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2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
G protein-coupled receptor P2Y ...... intenance of human hair growth
@ast
G protein-coupled receptor P2Y ...... intenance of human hair growth
@en
G protein-coupled receptor P2Y ...... intenance of human hair growth
@en-gb
G protein-coupled receptor P2Y ...... intenance of human hair growth
@nl
type
label
G protein-coupled receptor P2Y ...... intenance of human hair growth
@ast
G protein-coupled receptor P2Y ...... intenance of human hair growth
@en
G protein-coupled receptor P2Y ...... intenance of human hair growth
@en-gb
G protein-coupled receptor P2Y ...... intenance of human hair growth
@nl
altLabel
G protein–coupled receptor P2Y ...... intenance of human hair growth
@en
prefLabel
G protein-coupled receptor P2Y ...... intenance of human hair growth
@ast
G protein-coupled receptor P2Y ...... intenance of human hair growth
@en
G protein-coupled receptor P2Y ...... intenance of human hair growth
@en-gb
G protein-coupled receptor P2Y ...... intenance of human hair growth
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
G protein-coupled receptor P2Y ...... intenance of human hair growth
@en
P2093
Gerhard J Molderings
Ivar von Kügelgen
Katrin Voss
Khalid Al Aboud
Regina C Betz
Sandra M Pasternack
Thomas Franz
Young-Ae Lee
P2860
P2888
P304
P3181
P356
10.1038/NG.84
P407
P577
2008-03-01T00:00:00Z
P5875
P6179
1034952487