Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1)
about
Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placentaIdentification of Cys140 in helix 4 as an exofacial cysteine residue within the substrate-translocation channel of rat equilibrative nitrobenzylthioinosine (NBMPR)-insensitive nucleoside transporter rENT2Cloned blood-brain barrier adenosine transporter is identical to the rat concentrative Na+ nucleoside cotransporter CNT2.Simultaneous expression of hCNT1-CFP and hENT1-YFP in Madin-Darby canine kidney cells. Localization and vectorial transport studies.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Ribavirin resistance in hepatitis C virus replicon-containing cell lines conferred by changes in the cell line or mutations in the replicon RNA.Acyclovir, ganciclovir, and zidovudine transfer into rat milk.Specificity of human and rat orthologs of the concentrative nucleoside transporter, SPNT.Mechanisms and clinical implications of renal drug excretion.Molecular biology and regulation of nucleoside and nucleobase transporter proteins in eukaryotes and prokaryotes.A conformationally mobile cysteine residue (Cys-561) modulates Na+ and H+ activation of human CNT3Challenges for the development of ribonucleoside analogues as inducers of error catastrophe.Few Drugs Display Flip-Flop Pharmacokinetics and These Are Primarily Associated with Classes 3 and 4 of the BDDCSDifferent modes of transport for 3H-thymidine, 3H-FLT, and 3H-FMAU in proliferating and nonproliferating human tumor cells.Concentrative nucleoside transporter 1 (hCNT1) promotes phenotypic changes relevant to tumor biology in a translocation-independent mannerThe role of transporters in the toxicity of nucleoside and nucleotide analogs.Conserved glutamate residues Glu-343 and Glu-519 provide mechanistic insights into cation/nucleoside cotransport by human concentrative nucleoside transporter hCNT3Substituted cysteine accessibility method analysis of human concentrative nucleoside transporter hCNT3 reveals a novel discontinuous region of functional importance within the CNT family motif (G/A)XKX3NEFVA(Y/M/F).Red fluorescent protein pH biosensor to detect concentrative nucleoside transportAdenosine receptors: expression, function and regulation.ABC transporters and their role in nucleoside and nucleotide drug resistance.Functional production and reconstitution of the human equilibrative nucleoside transporter (hENT1) in Saccharomyces cerevisiae. Interaction of inhibitors of nucleoside transport with recombinant hENT1 and a glycosylation-defective derivative (hENT1/Multifaceted roles of extracellular DNA in bacterial physiology.A proton-mediated conformational shift identifies a mobile pore-lining cysteine residue (Cys-561) in human concentrative nucleoside transporter 3.Identification and functional characterization of the first nucleobase transporter in mammals: implication in the species difference in the intestinal absorption mechanism of nucleobases and their analogs between higher primates and other mammalsHepatocyte nuclear factor-4alpha and bile acids regulate human concentrative nucleoside transporter-1 gene expression.Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line.Identification of 8-aminoadenosine derivatives as a new class of human concentrative nucleoside transporter 2 inhibitors.Substituted cysteine accessibility method (SCAM) analysis of the transport domain of human concentrative nucleoside transporter 3 (hCNT3) and other family members reveals features of structural and functional importanceInterferon-gamma regulates nucleoside transport systems in macrophages through signal transduction and activator of transduction factor 1 (STAT1)-dependent and -independent signalling pathways.Cysteine-accessibility analysis of transmembrane domains 11-13 of human concentrative nucleoside transporter 3.Characterization of nucleoside transport systems in cultured rat epididymal epithelium.Guanine nucleosides and Jurkat cell death: roles of ATP depletion and accumulation of deoxyribonucleotides.An ancient prevertebrate Na+-nucleoside cotransporter (hfCNT) from the Pacific hagfish (Eptatretus stouti).Electrophysiological characterization of a recombinant human Na+-coupled nucleoside transporter (hCNT1) produced in Xenopus oocytes.Transport of nucleosides and free purine and pyrimidine bases across the plasma membraneTransepithelial fluxes of adenosine and 2'-deoxyadenosine across human renal proximal tubule cells: roles of nucleoside transporters hENT1, hENT2, and hCNT3.Molecular determinants of acidic pH-dependent transport of human equilibrative nucleoside transporter 3.Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter); member 1Emerging Roles of Nucleoside Transporters.
P2860
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P2860
Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1)
description
1997 nî lūn-bûn
@nan
1997 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Molecular cloning and function ...... cleoside cotransporter (hCNT1)
@ast
Molecular cloning and function ...... cleoside cotransporter (hCNT1)
@en
Molecular cloning and function ...... cleoside cotransporter (hCNT1)
@en-gb
Molecular cloning and function ...... cleoside cotransporter (hCNT1)
@nl
type
label
Molecular cloning and function ...... cleoside cotransporter (hCNT1)
@ast
Molecular cloning and function ...... cleoside cotransporter (hCNT1)
@en
Molecular cloning and function ...... cleoside cotransporter (hCNT1)
@en-gb
Molecular cloning and function ...... cleoside cotransporter (hCNT1)
@nl
prefLabel
Molecular cloning and function ...... cleoside cotransporter (hCNT1)
@ast
Molecular cloning and function ...... cleoside cotransporter (hCNT1)
@en
Molecular cloning and function ...... cleoside cotransporter (hCNT1)
@en-gb
Molecular cloning and function ...... cleoside cotransporter (hCNT1)
@nl
P2093
P2860
P1476
Molecular cloning and function ...... cleoside cotransporter (hCNT1)
@en
P2093
P2860
P304
P356
10.1152/AJPCELL.1997.272.2.C707
P407
P433
P577
1997-02-01T00:00:00Z