TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton
about
Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinAThe early-onset torsion dystonia-associated protein, torsinA, displays molecular chaperone activity in vitroCSN complex controls the stability of selected synaptic proteins via a torsinA-dependent processArresting a Torsin ATPase reshapes the endoplasmic reticulumLULL1 retargets TorsinA to the nuclear envelope revealing an activity that is impaired by the DYT1 dystonia mutationLINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteinsRegulation of Torsin ATPases by LAP1 and LULL1Printor, a novel torsinA-interacting protein implicated in dystonia pathogenesisCerebellothalamocortical connectivity regulates penetrance in dystoniaStructural features and chaperone activity of the NudC protein family.Torsins: not your typical AAA+ ATPasesNon-muscle myosin II takes centre stage in cell adhesion and migrationA molecular mechanism underlying the neural-specific defect in torsinA mutant miceWhispering dysphonia (DYT4 dystonia) is caused by a mutation in the TUBB4 geneTorsinA hypofunction causes abnormal twisting movements and sensorimotor circuit neurodegenerationMutant human torsinA, responsible for early-onset dystonia, dominantly suppresses GTPCH expression, dopamine levels and locomotion in Drosophila melanogasterA novel function for the Caenorhabditis elegans torsin OOC-5 in nucleoporin localization and nuclear importDissecting Torsin/cofactor function at the nuclear envelope: a genetic studyAbnormal structure-function relationships in hereditary dystonia.Chemical enhancement of torsinA function in cell and animal models of torsion dystonia.Cell-autonomous alteration of dopaminergic transmission by wild type and mutant (DeltaE) TorsinA in transgenic mice.Interactions between nuclei and the cytoskeleton are mediated by SUN-KASH nuclear-envelope bridges.Mutant torsinA interacts with tyrosine hydroxylase in cultured cells.Lamin-binding ProteinsThe nuclear envelope localization of DYT1 dystonia torsinA-ΔE requires the SUN1 LINC complex component.Biochemical and cellular analysis of human variants of the DYT1 dystonia protein, TorsinA/TOR1AAbnormal nuclear envelope in the cerebellar Purkinje cells and impaired motor learning in DYT11 myoclonus-dystonia mouse modelsChd5 orchestrates chromatin remodelling during sperm development.Current Gaps in the Understanding of the Subcellular Distribution of Exogenous and Endogenous Protein TorsinA.A unique redox-sensing sensor II motif in TorsinA plays a critical role in nucleotide and partner binding.4-Phenylbutyrate attenuates the ER stress response and cyclic AMP accumulation in DYT1 dystonia cell models.Untethering the nuclear envelope and cytoskeleton: biologically distinct dystonias arising from a common cellular dysfunctionGenetic and clinical features of primary torsion dystonia.Torsin A Localization in the Mouse Cerebellar Synaptic Circuitry.Intracellular complexes of the early-onset torsion dystonia-associated AAA+ ATPase TorsinA.Static retention of the lumenal monotopic membrane protein torsinA in the endoplasmic reticulum.Making the LINC: SUN and KASH protein interactions.Inherited isolated dystonia: clinical genetics and gene function.An inside-out origin for the eukaryotic cell.Evolution: functional evolution of nuclear structure.
P2860
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P248
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P2860
TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
TorsinA binds the KASH domain ...... lear envelope and cytoskeleton
@ast
TorsinA binds the KASH domain ...... lear envelope and cytoskeleton
@en
TorsinA binds the KASH domain ...... lear envelope and cytoskeleton
@en-gb
TorsinA binds the KASH domain ...... lear envelope and cytoskeleton
@nl
type
label
TorsinA binds the KASH domain ...... lear envelope and cytoskeleton
@ast
TorsinA binds the KASH domain ...... lear envelope and cytoskeleton
@en
TorsinA binds the KASH domain ...... lear envelope and cytoskeleton
@en-gb
TorsinA binds the KASH domain ...... lear envelope and cytoskeleton
@nl
prefLabel
TorsinA binds the KASH domain ...... lear envelope and cytoskeleton
@ast
TorsinA binds the KASH domain ...... lear envelope and cytoskeleton
@en
TorsinA binds the KASH domain ...... lear envelope and cytoskeleton
@en-gb
TorsinA binds the KASH domain ...... lear envelope and cytoskeleton
@nl
P2093
P2860
P921
P3181
P356
P1476
TorsinA binds the KASH domain ...... lear envelope and cytoskeleton
@en
P2093
Arnoud Sonnenberg
Brian P Niland
Daniel Irimia
Flávia C Nery
Jeffrey Hewett
Jonathan Farley
Xandra O Breakefield
P2860
P304
P3181
P356
10.1242/JCS.029454
P407
P577
2008-10-15T00:00:00Z