Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation
about
beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2The interaction of Src and RACK1 is enhanced by activation of protein kinase C and tyrosine phosphorylation of RACK1RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of src tyrosine kinases and growth of NIH 3T3 cellsProtein-tyrosine-phosphatase-mediated epidermal growth factor (EGF) receptor transinactivation and EGF receptor-independent stimulation of mitogen-activated protein kinase by bradykinin in A431 cellsThe m3 muscarinic acetylcholine receptor is coupled to mitogen-activated protein kinase via protein kinase C and epidermal growth factor receptor kinaseSU6656, a selective src family kinase inhibitor, used to probe growth factor signalingActivation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffoldsInternational Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapyExpansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 alpha subunits plus betagamma dimersTyrosine kinase signalling in breast cancer. Epidermal growth factor receptor: convergence point for signal integration and diversificationTyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer.Delta opioid activation of the mitogen-activated protein kinase cascade does not require transphosphorylation of receptor tyrosine kinasesSignaling and regulation of G protein-coupled receptors in airway smooth muscleHarnessing the genome for characterization of G-protein coupled receptors in cancer pathogenesisHuman epidermal growth factor receptor signaling in acute lung injuryThe relationship between the MMP system, adrenoceptors and phosphoprotein phosphatasesUnravelling the molecular complexity of GPCR-mediated EGFR transactivation using functional genomics approachesRegulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptorsRegulated association of microtubule-associated protein 2 (MAP2) with Src and Grb2: evidence for MAP2 as a scaffolding proteinInvolvement of lipoxygenase in lysophosphatidic acid-stimulated hydrogen peroxide release in human HaCaT keratinocytesSrc-family tyrosine kinases, phosphoinositide 3-kinase and Gab1 regulate extracellular signal-regulated kinase 1 activation induced by the type A endothelin-1 G-protein-coupled receptorTumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc.G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathwayEmployment of the epidermal growth factor receptor in growth factor-independent signaling pathwaysThe Gβγ-Src signaling pathway regulates TNF-induced necroptosis via control of necrosome translocationSrc homology 3 binding sites in the P2Y2 nucleotide receptor interact with Src and regulate activities of Src, proline-rich tyrosine kinase 2, and growth factor receptors.Direct binding of activated c-Src to the beta 3-adrenergic receptor is required for MAP kinase activation.Neurotensin stimulates mitogenesis of prostate cancer cells through a novel c-Src/Stat5b pathway.Angiotensin II stimulates ERK via two pathways in epithelial cells: protein kinase C suppresses a G-protein coupled receptor-EGF receptor transactivation pathway.An EGF receptor/Ral-GTPase signaling cascade regulates c-Src activity and substrate specificity.Mechanism of biological synergy between cellular Src and epidermal growth factor receptorMolecular mechanisms of ATP and insulin synergistic stimulation of coronary artery smooth muscle growth.Biasing the prostaglandin F2α receptor responses toward EGFR-dependent transactivation of MAPK.Angiotensin receptors: molecular biology and signalling.The m1 muscarinic acetylcholine receptor transactivates the EGF receptor to modulate ion channel activitySignal pathways mediating oxytocin stimulation of prostaglandin synthesis in select target cells.Tyrosine phosphorylation of the alpha subunit of transducin and its association with Src in photoreceptor rod outer segmentsBradykinin B(2) receptor-mediated mitogen-activated protein kinase activation in COS-7 cells requires dual signaling via both protein kinase C pathway and epidermal growth factor receptor transactivation.Angiotensin II stimulates fibronectin protein synthesis via a Gβγ/arachidonic acid-dependent pathway.Specific interaction of Gαi3 with the Oa1 G-protein coupled receptor controls the size and density of melanosomes in retinal pigment epithelium.
P2860
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P2860
Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation
description
1997 nî lūn-bûn
@nan
1997 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Gbetagamma subunits mediate Sr ...... ceptor-mediated Ras activation
@ast
Gbetagamma subunits mediate Sr ...... ceptor-mediated Ras activation
@en
Gbetagamma subunits mediate Sr ...... ceptor-mediated Ras activation
@en-gb
Gbetagamma subunits mediate Sr ...... ceptor-mediated Ras activation
@nl
type
label
Gbetagamma subunits mediate Sr ...... ceptor-mediated Ras activation
@ast
Gbetagamma subunits mediate Sr ...... ceptor-mediated Ras activation
@en
Gbetagamma subunits mediate Sr ...... ceptor-mediated Ras activation
@en-gb
Gbetagamma subunits mediate Sr ...... ceptor-mediated Ras activation
@nl
prefLabel
Gbetagamma subunits mediate Sr ...... ceptor-mediated Ras activation
@ast
Gbetagamma subunits mediate Sr ...... ceptor-mediated Ras activation
@en
Gbetagamma subunits mediate Sr ...... ceptor-mediated Ras activation
@en-gb
Gbetagamma subunits mediate Sr ...... ceptor-mediated Ras activation
@nl
P2093
P921
P3181
P356
P1476
Gbetagamma subunits mediate Sr ...... ceptor-mediated Ras activation
@en
P2093
D K Luttrell
G J Della Rocca
L M Luttrell
R J Lefkowitz
T van Biesen
P304
P3181
P356
10.1074/JBC.272.7.4637
P407
P577
1997-02-14T00:00:00Z