DISC1 regulates primary cilia that display specific dopamine receptors
about
A method for measuring electrical signals in a primary ciliumICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transportThe spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesisIns and outs of GPCR signaling in primary ciliaPrimary cilia in the developing and mature brainPrimary cilium and sonic hedgehog signaling during neural tube patterning: role of GPCRs and second messengersDISC1-binding proteins in neural development, signalling and schizophreniaDISC1: Structure, Function, and Therapeutic Potential for Major Mental IllnessA simple cell-based assay reveals that diverse neuropsychiatric risk genes converge on primary ciliaLack of dopaminergic inputs elongates the primary cilia of striatal neuronsG protein beta 5 is targeted to D2-dopamine receptor-containing biochemical compartments and blocks dopamine-dependent receptor internalizationThe XLID protein PQBP1 and the GTPase Dynamin 2 define a signaling link that orchestrates ciliary morphogenesis in postmitotic neuronsThe centrosomal protein pericentrin identified at the basal body complex of the connecting cilium in mouse photoreceptorsTargeting of vasoactive intestinal peptide receptor 2, VPAC2, a secretin family G-protein coupled receptor, to primary cilia.Tubby is required for trafficking G protein-coupled receptors to neuronal ciliaTrafficking to the primary cilium membrane.Primary Cilia as a Possible Link between Left-Right Asymmetry and Neurodevelopmental Diseases.Cilioplasm is a cellular compartment for calcium signaling in response to mechanical and chemical stimuli.Hippocampal and cortical primary cilia are required for aversive memory in mice.A chemical screen identifies class a g-protein coupled receptors as regulators of cilia.GPR88 reveals a discrete function of primary cilia as selective insulators of GPCR cross-talkStructural analysis of intermolecular interactions in the kinesin adaptor complex fasciculation and elongation protein zeta 1/ short coiled-coil protein (FEZ1/SCOCO)Mutant DISC1 affects methamphetamine-induced sensitization and conditioned place preference: a comorbidity model.Disc1 regulates both β-catenin-mediated and noncanonical Wnt signaling during vertebrate embryogenesis.Identification of G Protein-Coupled Receptors (GPCRs) in Primary Cilia and Their Possible Involvement in Body Weight Control.Dopamine receptors reveal an essential role of IFT-B, KIF17, and Rab23 in delivering specific receptors to primary ciliaDopamine receptor 1 localizes to neuronal cilia in a dynamic process that requires the Bardet-Biedl syndrome proteins.Sonic hedgehog functions upstream of disrupted-in-schizophrenia 1 (disc1): implications for mental illness.DISC1 genetics, biology and psychiatric illnessSmoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary ciliumType 3 Adenylyl Cyclase and Somatostatin Receptor 3 Expression Persists in Aged Rat Neocortical and Hippocampal Neuronal Cilia.Cilia in the nervous system: linking cilia function and neurodevelopmental disorders.Role of cilia in normal pancreas function and in diseased states.Tubby family proteins are adapters for ciliary trafficking of integral membrane proteinsThe primary cilium as a cellular receiver: organizing ciliary GPCR signalingGenome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci.Cilia and Obesity.Cilia, tubby mice, and obesityPrefronto-striatal physiology is associated with schizotypy and is modulated by a functional variant of DRD2Using Primary Neurosphere Cultures to Study Primary Cilia.
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P2860
DISC1 regulates primary cilia that display specific dopamine receptors
description
2010 nî lūn-bûn
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2010 թուականին հրատարակուած գիտական յօդուած
@hyw
2010 թվականին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年论文
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name
DISC1 regulates primary cilia that display specific dopamine receptors
@ast
DISC1 regulates primary cilia that display specific dopamine receptors
@en
DISC1 regulates primary cilia that display specific dopamine receptors
@en-gb
DISC1 regulates primary cilia that display specific dopamine receptors
@nl
type
label
DISC1 regulates primary cilia that display specific dopamine receptors
@ast
DISC1 regulates primary cilia that display specific dopamine receptors
@en
DISC1 regulates primary cilia that display specific dopamine receptors
@en-gb
DISC1 regulates primary cilia that display specific dopamine receptors
@nl
prefLabel
DISC1 regulates primary cilia that display specific dopamine receptors
@ast
DISC1 regulates primary cilia that display specific dopamine receptors
@en
DISC1 regulates primary cilia that display specific dopamine receptors
@en-gb
DISC1 regulates primary cilia that display specific dopamine receptors
@nl
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DISC1 regulates primary cilia that display specific dopamine receptors
@en
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Aaron Marley
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10.1371/JOURNAL.PONE.0010902
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2010-01-01T00:00:00Z