Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation
about
Birds, primates, and spoken language origins: behavioral phenotypes and neurobiological substrates.Brain evolution by brain pathway duplication.A single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domainsThe role of heparan sulfate deficiency in autistic phenotype: potential involvement of Slit/Robo/srGAPs-mediated dendritic spine formationGenetic variation and the de novo assembly of human genomesGenetic changes shaping the human brainComparative primate genomics: emerging patterns of genome content and dynamicsNew genes contribute to genetic and phenotypic novelties in human evolutionBrain evolution and development: adaptation, allometry and constraintThe inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cellsThe autism and schizophrenia associated gene CYFIP1 is critical for the maintenance of dendritic complexity and the stabilization of mature spinesCan a few non-coding mutations make a human brain?On the Evolving Biology of LanguagePossible functional links among brain- and skull-related genes selected in modern humansConvergent differential regulation of SLIT-ROBO axon guidance genes in the brains of vocal learnersOn the relationships of postcanine tooth size with dietary quality and brain volume in primates: implications for hominin evolutionIn with the old, in with the new: the promiscuity of the duplication process engenders diverse pathways for novel gene creationForce-control at cellular membranesGenomic divergence and brain evolution: How regulatory DNA influences development of the cerebral cortex2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain SizeStructural History of Human SRGAP2 ProteinsF-BAR family proteins, emerging regulators for cell membrane dynamic changes-from structure to human diseases.Why primate models matter.Decoding human gene expression signatures in the brainEvolution of genetic and genomic features unique to the human lineage.Synthesis of 53 tissue and cell line expression QTL datasets reveals master eQTLs.Activity-dependent dendritic spine neck changes are correlated with synaptic strength.Neuroscience: Genes and human brain evolution.Evolutionary insights into premetazoan functions of the neuronal protein homer.In transition: primate genomics at a time of rapid change.Cortical evolution: judge the brain by its cover.Chimaerin suppresses Rac1 activation at the apical membrane to maintain the cyst structureNew genes as drivers of phenotypic evolution.New gene evolution: little did we knowRegulation of cerebral cortex development by Rho GTPases: insights from in vivo studies.Fine-tuning of neurogenesis is essential for the evolutionary expansion of the cerebral cortexNeurodevelopmental LincRNA Microsyteny Conservation and Mammalian Brain Size Evolution.Early evolutionary history and genomic features of gene duplicates in the human genome.Functional test of PCDHB11, the most human-specific neuronal surface proteinNew genes drive the evolution of gene interaction networks in the human and mouse genomes
P2860
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P2860
Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Inhibition of SRGAP2 function ...... eoteny during spine maturation
@ast
Inhibition of SRGAP2 function ...... eoteny during spine maturation
@en
Inhibition of SRGAP2 function ...... eoteny during spine maturation
@en-gb
Inhibition of SRGAP2 function ...... eoteny during spine maturation
@nl
type
label
Inhibition of SRGAP2 function ...... eoteny during spine maturation
@ast
Inhibition of SRGAP2 function ...... eoteny during spine maturation
@en
Inhibition of SRGAP2 function ...... eoteny during spine maturation
@en-gb
Inhibition of SRGAP2 function ...... eoteny during spine maturation
@nl
prefLabel
Inhibition of SRGAP2 function ...... eoteny during spine maturation
@ast
Inhibition of SRGAP2 function ...... eoteny during spine maturation
@en
Inhibition of SRGAP2 function ...... eoteny during spine maturation
@en-gb
Inhibition of SRGAP2 function ...... eoteny during spine maturation
@nl
P2093
P2860
P921
P3181
P1433
P1476
Inhibition of SRGAP2 function ...... eoteny during spine maturation
@en
P2093
Anirvan Ghosh
Cécile Charrier
Jacqueline de Marchena
Jaeda Coutinho-Budd
Ji-Eun Kim
Kaumudi Joshi
Nelle Lambert
Pierre Vanderhaeghen
Takayuki Sassa
Wei-Lin Jin
P2860
P304
P3181
P356
10.1016/J.CELL.2012.03.034
P407
P577
2012-05-11T00:00:00Z