Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130
about
Evolutionary divergence and functions of the human interleukin (IL) gene familyInterleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietinA functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunitsSelective expression of an interleukin-12 receptor component by human T helper 1 cellsTwo mutational hotspots in the interleukin-2 receptor gamma chain gene causing human X-linked severe combined immunodeficiencyDefining the functional states of Th17 cellsIL-12Rβ1 deficiency: mutation update and description of the IL12RB1 variation databaseStructural Organization of a Full-Length gp130/LIF-R Cytokine Receptor Transmembrane ComplexInterleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytesRole of beta1 and beta2 subunits of the interleukin-12 receptor in determining T helper 1/T helper 2 responses in vivo in the ratResidual type 1 immunity in patients genetically deficient for interleukin 12 receptor beta1 (IL-12Rbeta1): evidence for an IL-12Rbeta1-independent pathway of IL-12 responsiveness in human T cellsIL-12 RB1 genetic variants contribute to human susceptibility to severe acute respiratory syndrome infection among Chinese.The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexesIL-12 as a therapeutic target for pharmacological modulation in immune-mediated and inflammatory diseases: regulation of T helper 1/T helper 2 responsesCytokines in asthma.Mycobacterium tuberculosis infection induces il12rb1 splicing to generate a novel IL-12Rbeta1 isoform that enhances DC migration.Hydrolysis of interleukin-12 by Porphyromonas gingivalis major cysteine proteinases may affect local gamma interferon accumulation and the Th1 or Th2 T-cell phenotype in periodontitisIL-12 family cytokines: immunological playmakersSignaling pathways that lead to the silencing of the interleukin-4-producing potential in Th1 cells.Anti-inflammatory cytokines in asthma and allergy: interleukin-10, interleukin-12, interferon-gamma.The IL-12Rbeta2 gene functions as a tumor suppressor in human B cell malignancies.Nitric oxide preferentially induces type 1 T cell differentiation by selectively up-regulating IL-12 receptor beta 2 expression via cGMPActivation of transmembrane cell-surface receptors via a common mechanism? The "rotation model".IL12Rβ1ΔTM is a secreted product of il12rb1 that promotes control of extrapulmonary tuberculosisIL12Rβ1: the cytokine receptor that we used to know.IL12B expression is sustained by a heterogenous population of myeloid lineages during tuberculosis.Endogenous IL-12 triggers an antiangiogenic program in melanoma cells.Interferon gamma-independent effects of interleukin 12 administered during acute or established infection due to Leishmania major.Early control of Mycobacterium tuberculosis infection requires il12rb1 expression by rag1-dependent lineages.Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4Interleukin 12: a potential link between nerve cells and the immune response in inflammatory disorders.Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination.Design of a Phase I Clinical Trial to Evaluate M032, a Genetically Engineered HSV-1 Expressing IL-12, in Patients with Recurrent/Progressive Glioblastoma Multiforme, Anaplastic Astrocytoma, or Gliosarcoma.Interleukin-35: odd one out or part of the family?Characterization of a novel subset of CD8(+) T cells that expands in patients receiving interleukin-12.Human interleukin 23 receptor induces cell apoptosis in mammalian cells by intrinsic mitochondrial pathway associated with the down-regulation of RAS/mitogen-activated protein kinase and signal transducers and activators of transcription factor 3 siCytokines and Chemokines in Mycobacterium tuberculosis Infection.The role of interleukin-12 on modulating myeloid-derived suppressor cells, increasing overall survival and reducing metastasis.A novel class of anti-IL-12p40 antibodies: potent neutralization via inhibition of IL-12-IL-12Rβ2 and IL-23-IL-23R.
P2860
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P2860
Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130
description
1994 nî lūn-bûn
@nan
1994 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Expression cloning of a human ...... with strong homology to gp130
@ast
Expression cloning of a human ...... with strong homology to gp130
@en
Expression cloning of a human ...... with strong homology to gp130
@en-gb
Expression cloning of a human ...... with strong homology to gp130
@nl
type
label
Expression cloning of a human ...... with strong homology to gp130
@ast
Expression cloning of a human ...... with strong homology to gp130
@en
Expression cloning of a human ...... with strong homology to gp130
@en-gb
Expression cloning of a human ...... with strong homology to gp130
@nl
prefLabel
Expression cloning of a human ...... with strong homology to gp130
@ast
Expression cloning of a human ...... with strong homology to gp130
@en
Expression cloning of a human ...... with strong homology to gp130
@en-gb
Expression cloning of a human ...... with strong homology to gp130
@nl
P2093
P1476
Expression cloning of a human ...... with strong homology to gp130
@en
P2093
Chizzonite R
Minetti LJ
Warrier RR
P304
P407
P577
1994-07-01T00:00:00Z