Molecular cloning and characterization of a putative novel human osteoclast-specific 116-kDa vacuolar proton pump subunit
about
The vacuolar H+-ATPase: a universal proton pump of eukaryotesTGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and diseasea4, a unique kidney-specific isoform of mouse vacuolar H+-ATPase subunit aMolecular cloning and characterization of Atp6n1b: a novel fourth murine vacuolar H+-ATPase a-subunit geneThree subunit a isoforms of mouse vacuolar H(+)-ATPase. Preferential expression of the a3 isoform during osteoclast differentiationProperties of three isoforms of the 116-kDa subunit of vacuolar H+-ATPase from a single vertebrate species. Cloning, gene expression and protein characterization of functionally distinct isoforms in Gallus gallus.An extended nomenclature for mammalian V-ATPase subunit genes and splice variants.RNAi-mediated silencing of Atp6i and Atp6i haploinsufficiency prevents both bone loss and inflammation in a mouse model of periodontal diseaseIn silico analysis of autoimmune diseases and genetic relationships to vaccination against infectious diseases.Atp6v0d2 is an essential component of the osteoclast-specific proton pump that mediates extracellular acidification in bone resorption.A novel inhibitor of vacuolar ATPase, FR167356, which can discriminate between osteoclast vacuolar ATPase and lysosomal vacuolar ATPaseNovel treatments for osteoporosis.Targeting Atp6v1c1 Prevents Inflammation and Bone Erosion Caused by Periodontitis and Reveals Its Critical Function in OsteoimmunologyGenotype-phenotype relationship in human ATP6i-dependent autosomal recessive osteopetrosisRGS10-null mutation impairs osteoclast differentiation resulting from the loss of [Ca2+]i oscillation regulationSignaling networks that control the lineage commitment and differentiation of bone cells.Ac45 silencing mediated by AAV-sh-Ac45-RNAi prevents both bone loss and inflammation caused by periodontitis.Future anti-catabolic therapeutic targets in bone disease.Towards a better understanding and new therapeutics of osteopetrosis.A selective inhibitor of the osteoclastic V-H(+)-ATPase prevents bone loss in both thyroparathyroidectomized and ovariectomized ratsGα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway.Monocytes differentiation upon treatment with a peptide corresponding to the C-terminus of activated T cell-expressed Tirc7 protein.Novel mutation of TCIRG1 and clinical pictures of two infantile malignant osteopetrosis patients.The a3 isoform of the 100-kDa V-ATPase subunit is highly but differentially expressed in large (>or=10 nuclei) and small (<or= nuclei) osteoclasts.Vacuolar H(+)-ATPases. Targets for drug discovery?CCAAT/Enhancer-binding Protein α (C/EBPα) Is Important for Osteoclast Differentiation and Activity.Epiregulin (EREG) and human V-ATPase (TCIRG1): genetic variation, ethnicity and pulmonary tuberculosis susceptibility in Guinea-Bissau and The Gambia.Four subunit a isoforms of Caenorhabditis elegans vacuolar H+-ATPase. Cell-specific expression during development.C/EBPα is Regulated by the RANK Cytoplasmic IVVY535-538 Motif and Stimulates Osteoclastogenesis more Strongly than c-Fos.Identification and reconstitution of an isoform of the 116-kDa subunit of the vacuolar proton translocating ATPase.Molecular cloning and expression of three isoforms of the 100-kDa a subunit of the mouse vacuolar proton-translocating ATPase.
P2860
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P2860
Molecular cloning and characterization of a putative novel human osteoclast-specific 116-kDa vacuolar proton pump subunit
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Molecular cloning and characte ...... a vacuolar proton pump subunit
@ast
Molecular cloning and characte ...... a vacuolar proton pump subunit
@en
Molecular cloning and characte ...... a vacuolar proton pump subunit
@en-gb
Molecular cloning and characte ...... a vacuolar proton pump subunit
@nl
type
label
Molecular cloning and characte ...... a vacuolar proton pump subunit
@ast
Molecular cloning and characte ...... a vacuolar proton pump subunit
@en
Molecular cloning and characte ...... a vacuolar proton pump subunit
@en-gb
Molecular cloning and characte ...... a vacuolar proton pump subunit
@nl
prefLabel
Molecular cloning and characte ...... a vacuolar proton pump subunit
@ast
Molecular cloning and characte ...... a vacuolar proton pump subunit
@en
Molecular cloning and characte ...... a vacuolar proton pump subunit
@en-gb
Molecular cloning and characte ...... a vacuolar proton pump subunit
@nl
P2093
P921
P3181
P356
P1476
Molecular cloning and characte ...... a vacuolar proton pump subunit
@en
P2093
P304
P3181
P356
10.1006/BBRC.1996.0145
P407
P577
1996-01-26T00:00:00Z