Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1
about
Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporterCloning of the human thiamine transporter, a member of the folate transporter familyL-Carnitine transport in human placental brush-border membranes is mediated by the sodium-dependent organic cation transporter OCTN2Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognitionA human transporter protein that mediates the final excretion step for toxic organic cationsDiscovery of the ergothioneine transporterOATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamiliesStrategies of bacterial over expression of membrane transporters relevant in human health: the successful case of the three members of OCTN subfamilyRole of solute carriers in response to anticancer drugsTransporters at CNS barrier sites: obstacles or opportunities for drug delivery?Renal drug transporters and their significance in drug-drug interactionsBlood brain barrier: a challenge for effectual therapy of brain tumorsMutations of OCTN2, an organic cation/carnitine transporter, lead to deficient cellular carnitine uptake in primary carnitine deficiencyExpression and localization of organic cation/carnitine transporter OCTN2 in Caco-2 cellsFunctional domains in the carnitine transporter OCTN2, defective in primary carnitine deficiencyFunctional variants of OCTN cation transporter genes are associated with Crohn diseaseDevelopmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and RoctMolecular and functional characterization of organic cation/carnitine transporter family in miceEvolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence MotifsVentricular choline transport: a role for organic cation transporter 2 expressed in choroid plexusIdentity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brainCloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placentaA novel transporter of SLC22 family specifically transports prostaglandins and co-localizes with 15-hydroxyprostaglandin dehydrogenase in renal proximal tubulesImportance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts.PPAR alpha mediates transcriptional upregulation of novel organic cation transporters-2 and -3 and enzymes involved in hepatic carnitine synthesis.Dietary oxidised fat up regulates the expression of organic cation transporters in liver and small intestine and alters carnitine concentrations in liver, muscle and plasma of rats.The promise and perils of interpreting genetic associations in Crohn's disease.rOCT2 is a basolateral potential-driven carrier, not an organic cation/proton exchanger.Pharmacogenomics of diuretic drugs: data on rare monogenic disorders and on polymorphisms and requirements for further research.Evidence for the association of the SLC22A4 and SLC22A5 genes with type 1 diabetes: a case control study.Gene expression in a Drosophila model of mitochondrial disease.Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture modelsXenobiotic, bile acid, and cholesterol transporters: function and regulation.Structure of renal organic anion and cation transporters.Functional relevance of carnitine transporter OCTN2 to brain distribution of L-carnitine and acetyl-L-carnitine across the blood-brain barrier.Reduced hepatic uptake and intestinal excretion of organic cations in mice with a targeted disruption of the organic cation transporter 1 (Oct1 [Slc22a1]) geneSmall molecular drug transfer across the blood-brain barrier via carrier-mediated transport systems.Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters.Cytokine regulation of OCTN2 expression and activity in small and large intestineMechanisms and clinical implications of renal drug excretion.
P2860
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P2860
Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1
description
1997 nî lūn-bûn
@nan
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Cloning and characterization o ...... anic cation transporter, OCTN1
@ast
Cloning and characterization o ...... anic cation transporter, OCTN1
@en
Cloning and characterization o ...... anic cation transporter, OCTN1
@en-gb
Cloning and characterization o ...... anic cation transporter, OCTN1
@nl
type
label
Cloning and characterization o ...... anic cation transporter, OCTN1
@ast
Cloning and characterization o ...... anic cation transporter, OCTN1
@en
Cloning and characterization o ...... anic cation transporter, OCTN1
@en-gb
Cloning and characterization o ...... anic cation transporter, OCTN1
@nl
prefLabel
Cloning and characterization o ...... anic cation transporter, OCTN1
@ast
Cloning and characterization o ...... anic cation transporter, OCTN1
@en
Cloning and characterization o ...... anic cation transporter, OCTN1
@en-gb
Cloning and characterization o ...... anic cation transporter, OCTN1
@nl
P2093
P2860
P3181
P1433
P1476
Cloning and characterization o ...... anic cation transporter, OCTN1
@en
P2093
H Yabuuchi
P2860
P304
P3181
P356
10.1016/S0014-5793(97)01441-5
P407
P577
1997-12-08T00:00:00Z