DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death
about
The caspase-cleaved DAP5 protein supports internal ribosome entry site-mediated translation of death proteins.p97/DAP5 is a ribosome-associated factor that facilitates protein synthesis and cell proliferation by modulating the synthesis of cell cycle proteinsHuman eukaryotic translation initiation factor 4G (eIF4G) possesses two separate and independent binding sites for eIF4AA novel functional human eukaryotic translation initiation factor 4GInteraction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translationHuman eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4EStructure-function analysis of an evolutionary conserved protein, DAP3, which mediates TNF-alpha- and Fas-induced cell deathNovel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexesA novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translationLet-7 microRNAs are developmentally regulated in circulating human erythroid cellsStructural Analysis of the DAP5 MIF4G Domain and Its Interaction with eIF4ADeath-associated protein 4 binds MST1 and augments MST1-induced apoptosisSmall proteins: untapped area of potential biological importanceMass spectrometric analysis of the N terminus of translational initiation factor eIF4G-1 reveals novel isoforms.Eukaryote-specific domains in translation initiation factors: implications for translation regulation and evolution of the translation system.Identification of candidate genes with pro-apoptotic properties by functional screening of randomly fragmented cDNA libraries.Involvement of ribosomal proteins in regulating cell growth and apoptosis: translational modulation or recruitment for extraribosomal activity?DAP kinase and DAP-3: novel positive mediators of apoptosisInduction and maintenance of autonomous flock house virus RNA1 replication.Translation initiation factor modifications and the regulation of protein synthesis in apoptotic cells.Eukaryotic translation initiation factor 4GI and p97 promote cellular internal ribosome entry sequence-driven translationDAP-kinase: from functional gene cloning to establishment of its role in apoptosis and cancer.Assembly of the SLIP1-SLBP complex on histone mRNA requires heterodimerization and sequential binding of SLBP followed by SLIP1.Eukaryotic translation elongation factor 1A (eEF1A) domain I from S. cerevisiae is required but not sufficient for inter-species complementationThe transcripts of SFRP1,CEP63 and EIF4G2 genes are frequently downregulated in transitional cell carcinomas of the bladder.Drep-2 is a novel synaptic protein important for learning and memory.The effect of IFNgamma on the hepatocyte: cell cycle and apoptosis.Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI.Essential role of NAT1/p97/DAP5 in embryonic differentiation and the retinoic acid pathway.DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translationThe eIF4G-homolog p97 can activate translation independent of caspase cleavageInitiation factor modifications in the preapoptotic phase.Interleukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon gamma, nitric oxide, and apoptosis.NAT1/DAP5/p97 and atypical translational control in the Drosophila Circadian Oscillator.The BH3-only protein Bik/Blk/Nbk inhibits nuclear translocation of activated ERK1/2 to mediate IFNgamma-induced cell death.How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?Cap-independent translation by DAP5 controls cell fate decisions in human embryonic stem cells.Nat1 promotes translation of specific proteins that induce differentiation of mouse embryonic stem cells.Translational control gone awry: a new mechanism of tumorigenesis and novel targets of cancer treatments.Translational activation of uncapped mRNAs by the central part of human eIF4G is 5' end-dependent.
P2860
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P2860
DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
DAP-5, a novel homolog of euka ...... -induced programmed cell death
@ast
DAP-5, a novel homolog of euka ...... -induced programmed cell death
@en
DAP-5, a novel homolog of euka ...... -induced programmed cell death
@en-gb
DAP-5, a novel homolog of euka ...... -induced programmed cell death
@nl
type
label
DAP-5, a novel homolog of euka ...... -induced programmed cell death
@ast
DAP-5, a novel homolog of euka ...... -induced programmed cell death
@en
DAP-5, a novel homolog of euka ...... -induced programmed cell death
@en-gb
DAP-5, a novel homolog of euka ...... -induced programmed cell death
@nl
prefLabel
DAP-5, a novel homolog of euka ...... -induced programmed cell death
@ast
DAP-5, a novel homolog of euka ...... -induced programmed cell death
@en
DAP-5, a novel homolog of euka ...... -induced programmed cell death
@en-gb
DAP-5, a novel homolog of euka ...... -induced programmed cell death
@nl
P2093
P2860
P356
P1476
DAP-5, a novel homolog of euka ...... -induced programmed cell death
@en
P2093
P2860
P304
P356
10.1128/MCB.17.3.1615
P407
P577
1997-03-01T00:00:00Z