Molecular characterization of the novel basic helix-loop-helix protein DEC1 expressed in differentiated human embryo chondrocytes
about
Regulation of STRA13 by the von Hippel-Lindau tumor suppressor protein, hypoxia, and the UBC9/ubiquitin proteasome degradation pathwayExpression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock systemDec1 and Dec2 are regulators of the mammalian molecular clockFunctional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation. Interaction with BMAL1DEC1 modulates the circadian phase of clock gene expressionAbundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activationDown-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenesDEC1 and DEC2 Crosstalk between Circadian Rhythm and Tumor ProgressionStra13 homodimers repress transcription through class B E-box elementsBasic helix-loop-helix protein DEC1 promotes chondrocyte differentiation at the early and terminal stagesDec1 and Dec2 expression is disrupted in the suprachiasmatic nuclei of Clock mutant micemSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expressionDEC2 suppresses tumor proliferation and metastasis by regulating ERK/NF-κB pathway in gastric cancerBasic helix-loop-helix transcription factor DEC1 negatively regulates cyclin D1.Insulin induces the expression of the SHARP-2/Stra13/DEC1 gene via a phosphoinositide 3-kinase pathway.Hypoxic tumor microenvironment and cancer cell differentiation.Tumor suppression by p53: making cells senescent.Enhancement of cell adhesion and spreading by a cartilage-specific noncollagenous protein, cartilage matrix protein (CMP/Matrilin-1), via integrin alpha1beta1.The basic helix-loop-helix protein, sharp-1, represses transcription by a histone deacetylase-dependent and histone deacetylase-independent mechanism.The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter.SUMOylation of DEC1 protein regulates its transcriptional activity and enhances its stability.DEC1 is a downstream target of TGF-beta with sequence-specific transcriptional repressor activities.Gene expression in Atlantic salmon skin in response to infection with the parasitic copepod Lepeophtheirus salmonis, cortisol implant, and their combinationRhythmic expression of DEC1 and DEC2 in peripheral tissues: DEC2 is a potent suppressor for hepatic cytochrome P450s opposing DBP.Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins.DEC1 nuclear expression: a marker of differentiation grade in hepatocellular carcinomaTranscription-factor occupancy at HOT regions quantitatively predicts RNA polymerase recruitment in five human cell lines.MicroRNA Levels as Prognostic Markers for the Differentiation Potential of Human Mesenchymal Stromal Cell DonorsPER1 modulates SGLT1 transcription in vitro independent of E-box status.Identification of gene markers for formaldehyde exposure in humans.Overexpression of the DEC1 protein induces senescence in vitro and is related to better survival in esophageal squamous cell carcinoma.The rexinoid bexarotene represses cyclin D1 transcription by inducing the DEC2 transcriptional repressor.The rexinoid, bexarotene, prevents the development of premalignant lesions in MMTV-erbB2 mice.The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancersbHLH-Orange Transcription Factors in Development and Cancer.PI-3 kinase pathway can mediate the effect of TGF-beta1 in inducing the expression of SHARP-2 in LLC-PK1 cells.A fluorescence spotlight on the clockwork development and metabolism of bone.The transcription factor DEC1 (BHLHE40/STRA13/SHARP-2) is negatively associated with TNM stage in non-small-cell lung cancer and inhibits the proliferation through cyclin D1 in A549 and BE1 cells.DEC1 negatively regulates AMPK activity via LKB1.P/CAF rescues the Bhlhe40-mediated repression of MyoD transactivation.
P2860
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P2860
Molecular characterization of the novel basic helix-loop-helix protein DEC1 expressed in differentiated human embryo chondrocytes
description
1997 nî lūn-bûn
@nan
1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Molecular characterization of ...... ated human embryo chondrocytes
@ast
Molecular characterization of ...... ated human embryo chondrocytes
@en
Molecular characterization of ...... ated human embryo chondrocytes
@en-gb
Molecular characterization of ...... ated human embryo chondrocytes
@nl
type
label
Molecular characterization of ...... ated human embryo chondrocytes
@ast
Molecular characterization of ...... ated human embryo chondrocytes
@en
Molecular characterization of ...... ated human embryo chondrocytes
@en-gb
Molecular characterization of ...... ated human embryo chondrocytes
@nl
prefLabel
Molecular characterization of ...... ated human embryo chondrocytes
@ast
Molecular characterization of ...... ated human embryo chondrocytes
@en
Molecular characterization of ...... ated human embryo chondrocytes
@en-gb
Molecular characterization of ...... ated human embryo chondrocytes
@nl
P2093
P356
P1476
Molecular characterization of ...... ated human embryo chondrocytes
@en
P2093
K Nakamasu
M Tamagami
T Kawamoto
P356
10.1006/BBRC.1997.6960
P407
P577
1997-07-18T00:00:00Z