Novel role of signal transducer and activator of transcription 3 as a progesterone receptor coactivator in breast cancer

Novel role of signal transducer and activator of transcription 3 as a progesterone receptor coactivator in breast cancer

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http://www.wikidata.org/entity/Q24320860
Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer developmentHeregulin Co-opts PR Transcriptional Action Via Stat3 Role As a Coregulator to Drive Cancer Growth.Role of phosphorylation in progesterone receptor signaling and specificityProgesterone receptors, their isoforms and progesterone regulated transcriptionCyclin A2 and its associated kinase activity are required for optimal induction of progesterone receptor target genes in breast cancer cellsProgesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growthER and PR signaling nodes during mammary gland development.Uterine deletion of Gp130 or Stat3 shows implantation failure with increased estrogenic responses.Stat3 promotes invasion of esophageal squamous cell carcinoma through up-regulation of MMP2.Progesterone regulation of tissue factor depends on MEK1/2 activation and requires the proline-rich site on progesterone receptor.Progesterone receptors (PR) mediate STAT actions: PR and prolactin receptor signaling crosstalk in breast cancer models.MiR-126-3p regulates progesterone receptors and involves development and lactation of mouse mammary gland.
P2860

Novel role of signal transducer and activator of transcription 3 as a progesterone receptor coactivator in breast cancer

Item
http://www.wikidata.org/entity/Q24320860
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2011 nî lūn-bûn
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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Novel role of signal transduce ...... r coactivator in breast cancer
@ast
Novel role of signal transduce ...... r coactivator in breast cancer
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Novel role of signal transduce ...... r coactivator in breast cancer
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Novel role of signal transduce ...... r coactivator in breast cancer
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type
label
Novel role of signal transduce ...... r coactivator in breast cancer
@ast
Novel role of signal transduce ...... r coactivator in breast cancer
@en
Novel role of signal transduce ...... r coactivator in breast cancer
@en-gb
Novel role of signal transduce ...... r coactivator in breast cancer
@nl
prefLabel
Novel role of signal transduce ...... r coactivator in breast cancer
@ast
Novel role of signal transduce ...... r coactivator in breast cancer
@en
Novel role of signal transduce ...... r coactivator in breast cancer
@en-gb
Novel role of signal transduce ...... r coactivator in breast cancer
@nl
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Novel role of signal transduce ...... r coactivator in breast cancer
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P31
P356
10.1016/J.STEROIDS.2010.12.008
P407
P433
P478
P50
P577
P5875
P698
P921