A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine

A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine

Item
http://www.wikidata.org/entity/Q24322097
Expression and functional analysis of CYP2D6.24, CYP2D6.26, CYP2D6.27, and CYP2D7 isozymesNot so pseudo: the evolutionary history of protein phosphatase 1 regulatory subunit 2 and related pseudogenesSystematic identification of pseudogenes through whole genome expression evidence profilingCodeine and Morphine MetabolismMolecular evolution of the CYP2D subfamily in primates: purifying selection on substrate recognition sites without the frequent or long-tract gene conversionGenomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics.Ophthalmic drug delivery considerations at the cellular level: drug-metabolising enzymes and transporters.Alternative splicing within the human cytochrome P450 superfamily with an emphasis on the brain: The convolution continues.A role for CYP in the drug-hormone crosstalk of the brain.Whole-genome sequencing in personalized therapeutics.Cytochrome P450-mediated metabolism in brain: functional roles and their implications.Impact of physiological, pathological and environmental factors on the expression and activity of human cytochrome P450 2D6 and implications in precision medicine.Constitutive expression and localization of cytochrome P-450 1A1 in rat and human brain: presence of a splice variant form in human brain.Hatching enzyme of the ovoviviparous black rockfish Sebastes schlegelii- environmental adaptation of the hatching enzyme and evolutionary aspects of formation of the pseudogene.Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication.Occurrence, distribution and potential actions of CYP2D6 in the brain
P2860

A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine

Item
http://www.wikidata.org/entity/Q24322097
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
A frameshift mutation and alte ...... methylates codeine to morphine
@ast
A frameshift mutation and alte ...... methylates codeine to morphine
@en
A frameshift mutation and alte ...... methylates codeine to morphine
@en-gb
A frameshift mutation and alte ...... methylates codeine to morphine
@nl
type
label
A frameshift mutation and alte ...... methylates codeine to morphine
@ast
A frameshift mutation and alte ...... methylates codeine to morphine
@en
A frameshift mutation and alte ...... methylates codeine to morphine
@en-gb
A frameshift mutation and alte ...... methylates codeine to morphine
@nl
prefLabel
A frameshift mutation and alte ...... methylates codeine to morphine
@ast
A frameshift mutation and alte ...... methylates codeine to morphine
@en
A frameshift mutation and alte ...... methylates codeine to morphine
@en-gb
A frameshift mutation and alte ...... methylates codeine to morphine
@nl
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P1476
P2093
P2860
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P356
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P433
P478
P50
P577
P698
P921
P356
P1433
P1476
A frameshift mutation and alte ...... methylates codeine to morphine
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921