The Cohesin loading factor NIPBL recruits histone deacetylases to mediate local chromatin modifications
about
Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancerIsolated NIBPL missense mutations that cause Cornelia de Lange syndrome alter MAU2 interactionMutations and variants in the cohesion factor genes NIPBL, SMC1A, and SMC3 in a cohort of 30 unrelated patients with Cornelia de Lange syndromeMultiple organ system defects and transcriptional dysregulation in the Nipbl(+/-) mouse, a model of Cornelia de Lange SyndromeMultifactorial origins of heart and gut defects in nipbl-deficient zebrafish, a model of Cornelia de Lange SyndromeThe dystonia gene DYT1 is repressed by the transcription factor THAP1 (DYT6).Cell cycle-specific cleavage of Scc2 regulates its cohesin deposition activity.Localisation of the SMC loading complex Nipbl/Mau2 during mammalian meiotic prophase IFunctional characterization of NIPBL physiological splice variants and eight splicing mutations in patients with Cornelia de Lange syndromeA cohesin-independent role for NIPBL at promoters provides insights in CdLS.Cohesin mediates chromatin interactions that regulate mammalian β-globin expressionEnhanced expression of cohesin loading factor NIPBL confers poor prognosis and chemotherapy resistance in non-small cell lung cancerIdentification and Functional Characterization of Two Intronic NIPBL Mutations in Two Patients with Cornelia de Lange SyndromeCohesin codes - interpreting chromatin architecture and the many facets of cohesin function.NIPBL Controls RNA Biogenesis to Prevent Activation of the Stress Kinase PKR.Cornelia de Lange syndrome mutations in SMC1A or SMC3 affect binding to DNAMutation spectrum and genotype-phenotype correlation in Cornelia de Lange syndrome.Cohesin: a critical chromatin organizer in mammalian gene regulationCD40 signaling drives B lymphocytes into an intermediate memory-like state, poised between naïve and plasma cells.Etiology and pathogenesis of the cohesinopathies.Regional chromatin decompaction in Cornelia de Lange syndrome associated with NIPBL disruption can be uncoupled from cohesin and CTCF.Structure of the cohesin loader Scc2.Inactivation of the budding yeast cohesin loader Scc2 alters gene expression both globally and in response to a single DNA double strand breakA genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.Genetic basis of cohesinopathies.Identification of a novel de novo mutation in the NIPBL gene in an Iranian patient with Cornelia de Lange syndrome: A case report.Neural crest cell-specific inactivation of Nipbl or Mau2 during mouse development results in a late onset of craniofacial defects.Inhibition of NIPBL enhances the chemosensitivity of non-small-cell lung cancer cells via the DNA damage response and autophagy pathway.
P2860
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P2860
The Cohesin loading factor NIPBL recruits histone deacetylases to mediate local chromatin modifications
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The Cohesin loading factor NIP ...... local chromatin modifications
@ast
The Cohesin loading factor NIP ...... local chromatin modifications
@en
The Cohesin loading factor NIP ...... local chromatin modifications
@en-gb
The Cohesin loading factor NIP ...... local chromatin modifications
@nl
type
label
The Cohesin loading factor NIP ...... local chromatin modifications
@ast
The Cohesin loading factor NIP ...... local chromatin modifications
@en
The Cohesin loading factor NIP ...... local chromatin modifications
@en-gb
The Cohesin loading factor NIP ...... local chromatin modifications
@nl
prefLabel
The Cohesin loading factor NIP ...... local chromatin modifications
@ast
The Cohesin loading factor NIP ...... local chromatin modifications
@en
The Cohesin loading factor NIP ...... local chromatin modifications
@en-gb
The Cohesin loading factor NIP ...... local chromatin modifications
@nl
P2093
P2860
P921
P356
P1476
The Cohesin loading factor NIP ...... local chromatin modifications
@en
P2093
Frank J Kaiser
Heinz Gabriel
Manuela Wülling
Melanie Albrecht
Philipp Jahnke
Weizhen Xu
P2860
P304
P356
10.1093/NAR/GKN688
P407
P577
2008-11-01T00:00:00Z