Precursor convertases in the secretory pathway, cytosol and extracellular milieu
about
The proprotein convertase (PC) PCSK9 is inactivated by furin and/or PC5/6A: functional consequences of natural mutations and post-translational modificationsCell-surface processing of pro-ADAMTS9 by furinDifferential P1 arginine and lysine recognition in the prototypical proprotein convertase Kex2PCSK9 (Proprotein convertase subtilisin/kexin type 9) inhibitors: past, present, and the futureProprotein convertases [corrected] are responsible for proteolysis and inactivation of endothelial lipaseSubtilisin-like proprotein convertase expression, localization, and activity in the human retina and optic nerve headCharacterization of carboxypeptidase A6, an extracellular matrix peptidaseTranscriptome sequencing and developmental regulation of gene expression in Anopheles aquasalisEmbryonic gene expression and pro-protein processing of proSAAS during rodent developmentCathepsin L colocalizes with chromogranin a in chromaffin vesicles to generate active peptidesImplication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous systemA novel enediynyl peptide inhibitor of furin that blocks processing of proPDGF-A, B and proVEGF-C.Proteolytic fragments of chromogranins A and B represent major soluble components of chromaffin granules, illustrated by two-dimensional proteomics with NH(2)-terminal Edman peptide sequencing and MALDI-TOF MSA hybrid, de novo based, genome-wide database search approach applied to the sea urchin neuropeptidomeA histidine-rich linker region in peptidylglycine α-amidating monooxygenase has the properties of a pH sensor.Potential role of proprotein convertase SKI-1 in the mineralization of primary boneEffects of PCSK9 genetic variants on plasma LDL cholesterol levels and risk of premature myocardial infarction in the Italian populationDeletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouseMass spectrometry-based neuropeptidomics of secretory vesicles from human adrenal medullary pheochromocytoma reveals novel peptide products of prohormone processingLiving the PCSK9 adventure: from the identification of a new gene in familial hypercholesterolemia towards a potential new class of anticholesterol drugs.Proprotein convertase furin regulates apoptosis and proliferation of granulosa cells in the rat ovary.Unique biological function of cathepsin L in secretory vesicles for biosynthesis of neuropeptides.Zymogen activation and subcellular activity of subtilisin kexin isozyme 1/site 1 protease.Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter.Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's diseaseSubtilisin-like proteases of the malaria parasite.Human cathepsin V protease participates in production of enkephalin and NPY neuropeptide neurotransmitters.Neurokinin Bs and neurokinin B receptors in zebrafish-potential role in controlling fish reproductionLoss of endothelial furin leads to cardiac malformation and early postnatal death.Relationships between genetic polymorphisms of E670G in PCSK9 gene and coronary artery disease: a meta-analysisNeuropeptide-processing enzymes: applications for drug discovery.Extracellular matrix assembly: a multiscale deconstructionA Molecular Sensor To Characterize Arenavirus Envelope Glycoprotein Cleavage by Subtilisin Kexin Isozyme 1/Site 1 ProteaseNeuroproteases in peptide neurotransmission and neurodegenerative diseases: applications to drug discovery research.Protease pathways in peptide neurotransmission and neurodegenerative diseases.Mechanism of Folding and Activation of Subtilisin Kexin Isozyme-1 (SKI-1)/Site-1 Protease (S1P).Loss of Peripheral Protection in Pancreatic Islets by Proteolysis-Driven Impairment of VTCN1 (B7-H4) Presentation Is Associated with the Development of Autoimmune Diabetes.Emerging role of a phosphatonin in mineral homeostasis and its derangements.Signal integration during development: mechanisms of EGFR and Notch pathway function and cross-talk.The proprotein convertases are potential targets in the treatment of dyslipidemia.
P2860
Q24299848-F583E7BB-91F0-41D9-8216-B4A79DC34C14Q24307820-E100AF1B-2693-474E-A8F4-EF3870FC89D8Q27644405-9D9D0967-8624-47B4-BA77-2A965E3681C6Q28083595-8B243F8C-7141-4FD9-80A0-1F114EDAFF2FQ28115283-1F495243-153D-4FB8-A3CE-A0A01746DC40Q28240099-2043D2FE-CE9E-4F45-A2B4-DFAF2FD210A1Q28263785-F775B325-D841-4D42-B481-17FD61CCB212Q28540813-D2BA2092-4684-4786-B5C9-013D581F5858Q28576325-F60F5BF4-0E36-4453-AA5A-0B8E654EF866Q28579762-E77F523F-D162-419B-9DE8-943F203CB42CQ28587541-71F9DBB2-CF3D-4AAF-BF5D-FA5D0229B486Q30943394-F8783E64-FEF8-482C-804F-177E6C51B9A1Q33436933-5EA27094-6C16-49D7-8EBA-02581441A60CQ33517721-13D2AACF-137F-4539-B5C3-E567009FEE9EQ33556099-AC7F317C-42B5-4A99-84E8-9F0F1589E9B0Q33666370-B481553B-C915-43A9-96E0-A671E34461D9Q34188099-092BD615-F8E9-4239-BFD9-01C602A99E5AQ34233493-2A815259-4D5A-47C5-A041-68C748E43494Q34397442-A27738D5-12F0-4562-BDCA-632B9F8D483AQ34430377-2EF82113-EB1A-43AF-A664-7756A25C7DCCQ34589453-935B5D6B-38D7-4D6C-BBC8-00BF4FF88203Q34679073-A072853A-3F70-4553-9F93-2028D05FFDD5Q34774433-161896A9-18A3-4268-BE3A-C2F928F28554Q35234967-0C051EC3-D0A0-40AA-BCC0-38D905AD0C06Q35596997-220F21BD-2FE4-4191-8C04-6B811D468AB2Q35822049-061F5010-9A16-4EEC-B509-8D9DDF0D37A5Q35939830-2FD10033-85AB-4471-8EDD-F737551AD7BBQ36069004-E76CBA16-F66D-4B0D-B1B5-ADBA6622FAB3Q36172870-EAB67BFA-0C79-4779-9A3B-93EE52C316A5Q36182994-6E512FA6-AD1C-46C2-B071-0ABF14E60747Q36341621-E9E561FD-9FCE-4248-A6DC-898BF8F5A5C9Q36381030-B05EF86F-B288-4C8E-973A-F67EF4EE5186Q36434299-6942B697-2F05-47A7-94C3-E09ED9520B0DQ36454244-6D435C4E-3748-4E65-8FF0-4341F31AB33EQ36488794-80E7C7A9-50B6-47DC-A20B-1C202D96BDE6Q36518221-33B4D8BE-2D67-476B-AAC8-3B27516FD143Q36553893-6AE99077-6A94-4E2B-A8F7-1DEE5E0DF0A8Q36554782-7B357EA3-4808-4B32-8478-F7B6AA6817E9Q36648414-BB2C8B97-0BCE-4C50-BDE1-732C641AAEA2Q36757387-5952504F-543E-46CB-92EB-D1A03BAA3B1F
P2860
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
description
2002 nî lūn-bûn
@nan
2002 թուականին հրատարակուած գիտական յօդուած
@hyw
2002 թվականին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
@ast
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
@en
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
@en-gb
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
@nl
type
label
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
@ast
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
@en
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
@en-gb
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
@nl
prefLabel
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
@ast
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
@en
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
@en-gb
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
@nl
P356
P1476
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
@en
P2093
Nabil G Seidah
P356
10.1042/BSE0380079
P407
P50
P577
2002-01-01T00:00:00Z